6UHT

Crystal structure of BoNT/B receptor-binding domain in complex with VHH JLI-G10

Summary for 6UHT

• Entry DOI: 10.2210/pdb6uht/pdb
• Descriptor: Botulinum neurotoxin type B, JLI-G10 (3 entities in total)
• Functional Keywords: botulinum neurotoxin (bont), vhh, receptor-binding domain, toxin, antitoxin, toxin-antitoxin complex, toxin/antitoxin
• Biological source: Clostridium botulinum; More
• Total number of polymer chains: 4
• Total formula weight: 135151.42

Authors

Lam, K.,Jin, R. (deposition date: 2019-09-28, release date: 2020-03-04, Last modification date: 2023-10-11)

• Primary citation: Lam, K.,Tremblay, J.M.,Vazquez-Cintron, E.,Perry, K.,Ondeck, C.,Webb, R.P.,Mcnutt, P.M.,Shoemaker, C.B.,Jin, R.; Structural Insights into Rational Design of Single-Domain Antibody-Based Antitoxins against Botulinum Neurotoxins; Cell Rep, 30:2526-, 2020; DOI: 10.1016/j.celrep.2020.01.107

Experimental method

X-RAY DIFFRACTION (2.20001465977 Å)