4H34
Crystal structure of the tyrosine phosphatase SHP-2 with Q506P mutation
Summary for 4H34
Entry DOI | 10.2210/pdb4h34/pdb |
Related | 4GWF 4H1O |
Descriptor | Tyrosine-protein phosphatase non-receptor type 11, 1,2-ETHANEDIOL, GLYCEROL, ... (4 entities in total) |
Functional Keywords | alpha/beta proteins, sh2 domain, phosphatase domain, tyrosine phosphatase shp-2, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : Q06124 |
Total number of polymer chains | 1 |
Total formula weight | 64965.17 |
Authors | Qiu, W.,Lin, A.,Hutchinson, A.,Romanov, V.,Ruzanov, M.,Thompson, C.,Lam, K.,Kisselman, G.,Battaile, K.,Chirgadze, N.Y. (deposition date: 2012-09-13, release date: 2013-10-02, Last modification date: 2023-09-20) |
Primary citation | Qiu, W.,Lin, A.,Hutchinson, A.,Romanov, V.,Ruzanov, M.,Thompson, C.,Lam, K.,Kisselman, G.,Battaile, K.,Chirgadze, N.Y. Crystal structure of the tyrosine phosphatase SHP-2 with Q506P mutation To be Published, |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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