6UL6

Crystal Structure of BoNT/A-LCHn domain in complex with VNA ciA-D12/11/ciA-B5 and VHH ciA-H7

Summary for 6UL6

• Entry DOI: 10.2210/pdb6ul6/pdb
• Descriptor: BoNT/A, ciA-D12/11/ciA-B5, ciA-H7, ... (4 entities in total)
• Functional Keywords: botulinum neurotoxin (bont), vhh, toxin, antitoxin, toxin-antitoxin complex, toxin/antitoxin
• Biological source: Clostridium botulinum; More
• Total number of polymer chains: 3
• Total formula weight: 141990.96

Authors

Lam, K.,Jin, R. (deposition date: 2019-10-07, release date: 2020-03-04, Last modification date: 2023-10-11)

• Primary citation: Lam, K.,Tremblay, J.M.,Vazquez-Cintron, E.,Perry, K.,Ondeck, C.,Webb, R.,McNutt, P.M.,Shoemaker, C.B.,Jin, R.; Structural Insights into Rational Design of Single-Domain Antibody-Based Antitoxins against Botulinum Neurotoxins; Cell Rep, 30:2526-, 2020; DOI: 10.1016/j.celrep.2020.01.107

Experimental method

X-RAY DIFFRACTION (2.02000221988 Å)