6UI1

Crystal structure of BoNT/A-LCHn domain in complex with VHH ciA-D12, ciA-B5, and ciA-H7

Summary for 6UI1

• Entry DOI: 10.2210/pdb6ui1/pdb
• Descriptor: BoNT/A, ciA-H7, ciA-D12, ... (5 entities in total)
• Functional Keywords: botulinum neurotoxin (bont), vhh, receptor-binding domain, toxin, antitoxin, toxin-antitoxin complex, toxin/antitoxin
• Biological source: Clostridium botulinum; More
• Total number of polymer chains: 4
• Total formula weight: 141754.62

Authors

Lam, K.,Jin, R. (deposition date: 2019-09-29, release date: 2020-03-04, Last modification date: 2023-10-11)

• Primary citation: Lam, K.,Tremblay, J.M.,Vazquez-Cintron, E.,Perry, K.,Ondeck, C.,Webb, R.,McNutt, P.M.,Shoemaker, C.B.,Jin, R.; Structural Insights into Rational Design of Single-Domain Antibody-Based Antitoxins against Botulinum Neurotoxins; Cell Rep, 30:2526-, 2020; DOI: 10.1016/j.celrep.2020.01.107

Experimental method

X-RAY DIFFRACTION (2.20000858936 Å)