6UI1
Crystal structure of BoNT/A-LCHn domain in complex with VHH ciA-D12, ciA-B5, and ciA-H7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | BoNT/A | polymer | 873 | 100030.0 | 1 | UniProt (Q7B8V4) Pfam (PF01742) Pfam (PF07952) UniProt (by SIFTS) (P0DPI1) | Clostridium botulinum | BoNT/A1 neurotoxin,Bont/A1,Botulinum neurotoxin type A,Neurotoxin A,Neurotoxin BoNT,Neurotoxin type A,Peptidase M27 |
| 2 | B (B) | ciA-H7 | polymer | 123 | 13133.5 | 1 | Vicugna pacos | ||
| 3 | C (C) | ciA-D12 | polymer | 134 | 14404.2 | 1 | Vicugna pacos | ||
| 4 | D (D) | ciA-B5 | polymer | 130 | 14186.9 | 1 | Vicugna pacos | ||
| 5 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 524 | Chemie (HOH) |
Sequence modifications
A: 1 - 871 (UniProt: Q7B8V4)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
| Gln 224 | Glu 224 | conflict |
| Ala 363 | Arg 363 | conflict |
| Phe 366 | Tyr 366 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 141754.6 | |
| All* | Total formula weight | 141754.6 |
