4I51
Methyltransferase domain of HUMAN EUCHROMATIC HISTONE METHYLTRANSFERASE 1, mutant Y1211A
Replaces: 4H4HSummary for 4I51
Entry DOI | 10.2210/pdb4i51/pdb |
Descriptor | Histone-lysine N-methyltransferase EHMT1, H3K9 NE-ALLYL PEPTIDE, UNKNOWN PEPTIDE, ... (8 entities in total) |
Functional Keywords | ne-allyl peptide, structural genomics consortium, transferase-peptide complex, sgc, transferase/peptide |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q9H9B1 |
Total number of polymer chains | 5 |
Total formula weight | 70383.53 |
Authors | Dong, A.,Zeng, H.,Walker, J.R.,Islam, K.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Lou, M.,Min, J.,Wu, H.,Structural Genomics Consortium (SGC) (deposition date: 2012-11-28, release date: 2012-12-19, Last modification date: 2023-12-06) |
Primary citation | Islam, K.,Chen, Y.,Wu, H.,Bothwell, I.R.,Blum, G.J.,Zeng, H.,Dong, A.,Zheng, W.,Min, J.,Deng, H.,Luo, M. Defining efficient enzyme-cofactor pairs for bioorthogonal profiling of protein methylation. Proc.Natl.Acad.Sci.USA, 110:16778-16783, 2013 Cited by PubMed: 24082136DOI: 10.1073/pnas.1216365110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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