4I51
Methyltransferase domain of HUMAN EUCHROMATIC HISTONE METHYLTRANSFERASE 1, mutant Y1211A
Replaces: 4H4HEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, B) | Histone-lysine N-methyltransferase EHMT1 | polymer | 286 | 32795.2 | 2 | UniProt (Q9H9B1) Pfam (PF05033) Pfam (PF00856) | Homo sapiens (human) | Euchromatic histone-lysine N-methyltransferase 1, Eu-HMTase1, G9a-like protein 1, GLP, GLP1, Histone H3-K9 methyltransferase 5, H3-K9-HMTase 5, Lysine N-methyltransferase 1D |
| 2 | B, D (C, D) | H3K9 NE-ALLYL PEPTIDE | polymer | 9 | 1050.2 | 2 | UniProt (by SIFTS) (P68431) | Homo sapiens | |
| 3 | E (K) | UNKNOWN PEPTIDE | polymer | 13 | 1124.4 | 1 | |||
| 4 | F, U (A, B) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
| 5 | G, H, I, J, V... (A, B) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 6 | K, L, Z (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 7 | AA, M, N, O, P... (B, A) | UNKNOWN ATOM OR ION | non-polymer | 9 | Chemie (UNX) | ||||
| 8 | BA, CA, DA, EA (A, C, B, D) | water | water | 18.0 | 503 | Chemie (HOH) |
Sequence modifications
A, B: 951 - 1235 (UniProt: Q9H9B1)
| PDB | External Database | Details |
|---|---|---|
| Gly 950 | - | expression tag |
| Ala 1211 | Tyr 1242 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 68815.1 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 1568.4 | |
| All* | Total formula weight | 70383.5 |
