8S86

human PLD3 homodimer structure

Summary for 8S86

Entry DOI	10.2210/pdb8s86/pdb
EMDB information	19798
Descriptor	5'-3' exonuclease PLD3 (1 entity in total)
Functional Keywords	exonuclease, immune system
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	96116.03
Authors	Lammens, K. (deposition date: 2024-03-05, release date: 2024-05-15)
Primary citation	Berouti, M.,Lammens, K.,Heiss, M.,Hansbauer, L.,Bauernfried, S.,Stockl, J.,Pinci, F.,Piseddu, I.,Greulich, W.,Wang, M.,Jung, C.,Frohlich, T.,Carell, T.,Hopfner, K.P.,Hornung, V. Lysosomal endonuclease RNase T2 and PLD exonucleases cooperatively generate RNA ligands for TLR7 activation. Immunity, 2024 Cited by PubMed: 38697119 DOI: 10.1016/j.immuni.2024.04.010 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.8 Å)

Structure validation