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7KKJ
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STRUCTURE OF ANTI-SARS-COV-2 SPIKE NANOBODY MNB6
Descriptor:Synthetic nanobody mNb6, SULFATE ION, CHLORIDE ION
Authors:Schoof, M.S., Faust, B.F., Saunders, R.A., Sangwan, S., Rezelj, V., Hoppe, N., Boone, M., Billesboelle, C.B., Puchades, C., Azumaya, C.M., Kratochvil, H.T., Zimanyi, M., Desphande, I., Liang, J., Dickinson, S., Nguyen, H.C., Chio, C.M., Merz, G.E., Thompson, M.C., Diwanji, D., Schaefer, K., Anand, A.A., Dobzinski, N., Zha, B.S., Simoneau, C.R., Leon, K., White, K.M., Chio, U.S., Gupta, M., Jin, M., Li, F., Liu, Y., Zhang, K., Bulkley, D., Sun, M., Smith, A.M., Rizo, A.N., Moss, F., Brilot, A.F., Pourmal, S., Trenker, R., Pospiech, T., Gupta, S., Barsi-Rhyne, B., Belyy, V., Barile-Hill, A.W., Nock, S., Liu, Y., Krogan, N.J., Ralston, C.Y., Swaney, D.L., Garcia-Sastre, A., Ott, M., Vignuzzi, M., Walter, P., Manglik, A., QCRG Structural Biology Consortium
Deposit date:2020-10-27
Release date:2020-11-25
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science, 2020
7KKK
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SARS-COV-2 SPIKE IN COMPLEX WITH NEUTRALIZING NANOBODY NB6
Descriptor:SARS-CoV-2 spike glycoprotein, Synthetic nanobody Nb6, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Schoof, M.S., Faust, B.F., Saunders, R.A., Sangwan, S., Rezelj, V., Hoppe, N., Boone, M., Billesboelle, C.B., Puchades, C., Azumaya, C.M., Kratochvil, H.T., Zimanyi, M., Desphande, I., Liang, J., Dickinson, S., Nguyen, H.C., Chio, C.M., Merz, G.E., Thompson, M.C., Diwanji, D., Schaefer, K., Anand, A.A., Dobzinski, N., Zha, B.S., Simoneau, C.R., Leon, K., White, K.M., Chio, U.S., Gupta, M., Jin, M., Li, F., Liu, Y., Zhang, K., Bulkley, D., Sun, M., Smith, A.M., Rizo, A.N., Moss, F., Brilot, A.F., Pourmal, S., Trenker, R., Pospiech, T., Gupta, S., Barsi-Rhyne, B., Belyy, V., Barile-Hill, A.W., Nock, S., Liu, Y., Krogan, N.J., Ralston, C.Y., Swaney, D.L., Garcia-Sastre, A., Ott, M., Vignuzzi, M., Walter, P., Manglik, A., QCRG Structural Biology Consortium
Deposit date:2020-10-27
Release date:2020-11-11
Last modified:2020-11-25
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science, 2020
7KKL
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SARS-COV-2 SPIKE IN COMPLEX WITH NEUTRALIZING NANOBODY MNB6
Descriptor:SARS-CoV-2 spike glycoprotein, Synthetic nanobody mNb6, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Schoof, M.S., Faust, B.F., Saunders, R.A., Sangwan, S., Rezelj, V., Hoppe, N., Boone, M., Billesboelle, C.B., Puchades, C., Azumaya, C.M., Kratochvil, H.T., Zimanyi, M., Desphande, I., Liang, J., Dickinson, S., Nguyen, H.C., Chio, C.M., Merz, G.E., Thompson, M.C., Diwanji, D., Schaefer, K., Anand, A.A., Dobzinski, N., Zha, B.S., Simoneau, C.R., Leon, K., White, K.M., Chio, U.S., Gupta, M., Jin, M., Li, F., Liu, Y., Zhang, K., Bulkley, D., Sun, M., Smith, A.M., Rizo, A.N., Moss, F., Brilot, A.F., Pourmal, S., Trenker, R., Pospiech, T., Gupta, S., Barsi-Rhyne, B., Belyy, V., Barile-Hill, A.W., Nock, S., Liu, Y., Krogan, N.J., Ralston, C.Y., Swaney, D.L., Garcia-Sastre, A., Ott, M., Vignuzzi, M., Walter, P., Manglik, A., QCRG Structural Biology Consortium
Deposit date:2020-10-27
Release date:2020-11-11
Last modified:2020-11-25
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science, 2020
3V4J
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FIRST-IN-CLASS SMALL MOLECULE INHIBITORS OF THE SINGLE-STRAND DNA CYTOSINE DEAMINASE APOBEC3G
Descriptor:DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION, 4-[methyl(nitroso)amino]benzene-1,2-diol
Authors:Shandilya, S.M.D., Ali, A., Schiffer, C.A.
Deposit date:2011-12-15
Release date:2012-02-01
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:First-In-Class Small Molecule Inhibitors of the Single-Strand DNA Cytosine Deaminase APOBEC3G.
Acs Chem.Biol., 7, 2012
3V4K
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FIRST-IN-CLASS SMALL MOLECULE INHIBITORS OF THE SINGLE-STRAND DNA CYTOSINE DEAMINASE APOBEC3G
Descriptor:DNA dC->dU-editing enzyme APOBEC-3G, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Shandilya, S.M.D., Ali, A., Schiffer, C.A.
Deposit date:2011-12-15
Release date:2012-01-25
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:First-In-Class Small Molecule Inhibitors of the Single-Strand DNA Cytosine Deaminase APOBEC3G.
Acs Chem.Biol., 7, 2012
4IMY
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THE AFF4 SCAFFOLD BINDS HUMAN P-TEFB ADJACENT TO HIV TAT
Descriptor:Cyclin-dependent kinase 9, Cyclin-T1, AF4/FMR2 family member 4, ...
Authors:Alber, T., Schulze-Gahmen, U.
Deposit date:2013-01-03
Release date:2013-03-13
Last modified:2013-04-03
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat.
Elife, 2, 2013
5TP1
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THE STRUCTURE OF THE C-TERMINUS OF VIRULENCE PROTEIN INCE FROM CHLAMYDIA TRACHOMATIS BOUND TO MUS MUSCULUS SNX5-PX DOMAIN
Descriptor:Sorting nexin-5, Inclusion membrane protein E
Authors:Rosenberg, O., Czudnochowski, N.
Deposit date:2016-10-19
Release date:2017-08-30
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Chlamydia interfere with an interaction between the mannose-6-phosphate receptor and sorting nexins to counteract host restriction.
Elife, 6, 2017
6E5X
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CRYSTAL STRUCTURE OF EBOLA VIRUS VP30 C-TERMINUS/RBBP6 PEPTIDE COMPLEX
Descriptor:Minor nucleoprotein VP30, E3 ubiquitin-protein ligase RBBP6, CALCIUM ION
Authors:Liu, D., Small, G.I., Leung, D.W., Amarasinghe, G.K.
Deposit date:2018-07-23
Release date:2018-12-12
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Protein Interaction Mapping Identifies RBBP6 as a Negative Regulator of Ebola Virus Replication.
Cell, 175, 2018
7KDT
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HUMAN TOM70 IN COMPLEX WITH SARS COV2 ORF9B
Descriptor:Mitochondrial import receptor subunit TOM70, ORF9b protein
Authors:QCRG Structural Biology Consortium
Deposit date:2020-10-09
Release date:2020-10-21
Last modified:2020-11-04
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.
Science, 2020
171588
PDB entries from 2020-11-25