7LMS

Structure of human SetD3 methyl-transferase in complex with 2A protease from Coxsackievirus B3

Summary for 7LMS

Entry DOI	10.2210/pdb7lms/pdb
EMDB information	23441
Descriptor	Protease 2A, Actin-histidine N-methyltransferase, ZINC ION, ... (4 entities in total)
Functional Keywords	methyltransferase, viral protease, viral protein
Biological source	Coxsackievirus B3 (strain Nancy) More
Total number of polymer chains	2
Total formula weight	84517.42
Authors	Verba, K.A.,Schulze-Gahmen, U. (deposition date: 2021-02-05, release date: 2022-08-10, Last modification date: 2023-02-22)
Primary citation	Peters, C.E.,Schulze-Gahmen, U.,Eckhardt, M.,Jang, G.M.,Xu, J.,Pulido, E.H.,Bardine, C.,Craik, C.S.,Ott, M.,Gozani, O.,Verba, K.A.,Huttenhain, R.,Carette, J.E.,Krogan, N.J. Structure-function analysis of enterovirus protease 2A in complex with its essential host factor SETD3. Nat Commun, 13:5282-5282, 2022 Cited by PubMed: 36075902 DOI: 10.1038/s41467-022-32758-3 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.5 Å)

Structure validation