Author results

4ZWJ
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CRYSTAL STRUCTURE OF RHODOPSIN BOUND TO ARRESTIN BY FEMTOSECOND X-RAY LASER
Descriptor:Chimera protein of human Rhodopsin, mouse S-arrestin, and T4 Endolysin
Authors:Kang, Y., Zhou, X.E., Gao, X., He, Y., Liu, W., Ishchenko, A., Barty, A., White, T.A., Yefanov, O., Han, G.W., Xu, Q., de Waal, P.W., Ke, J., Tan, M.H.E., Zhang, C., Moeller, A., West, G.M., Pascal, B., Eps, N.V., Caro, L.N., Vishnivetskiy, S.A., Lee, R.J., Suino-Powell, K.M., Gu, X., Pal, K., Ma, J., Zhi, X., Boutet, S., Williams, G.J., Messerschmidt, M., Gati, C., Zatsepin, N.A., Wang, D., James, D., Basu, S., Roy-Chowdhury, S., Conrad, C., Coe, J., Liu, H., Lisova, S., Kupitz, C., Grotjohann, I., Fromme, R., Jiang, Y., Tan, M., Yang, H., Li, J., Wang, M., Zheng, Z., Li, D., Howe, N., Zhao, Y., Standfuss, J., Diederichs, K., Dong, Y., Potter, C.S., Carragher, B., Caffrey, M., Jiang, H., Chapman, H.N., Spence, J.C.H., Fromme, P., Weierstall, U., Ernst, O.P., Katritch, V., Gurevich, V.V., Griffin, P.R., Hubbell, W.L., Stevens, R.C., Cherezov, V., Melcher, K., Xu, H.E., GPCR Network (GPCR)
Deposit date:2015-05-19
Release date:2015-07-29
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (3.302 Å)
Cite:Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.
Nature, 523, 2015
5N6H
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STRUCTURE OF THE MEMBRANE INTEGRAL LIPOPROTEIN N-ACYLTRANSFERASE LNT FROM E. COLI
Descriptor:Apolipoprotein N-acyltransferase, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, GLYCEROL
Authors:Huang, C.-Y., Boland, C., Howe, N., Wiktor, M., Vogeley, L., Weichert, D., Bailey, J., Olieric, V., Wang, M., Caffrey, M.
Deposit date:2017-02-15
Release date:2017-07-12
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis.
Nat Commun, 8, 2017
5N6L
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STRUCTURE OF THE MEMBRANE INTEGRAL LIPOPROTEIN N-ACYLTRANSFERASE LNT C387A MUTANT FROM E. COLI
Descriptor:Apolipoprotein N-acyltransferase, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, GLYCEROL
Authors:Huang, C.-Y., Boland, C., Howe, N., Wiktor, M., Vogeley, L., Weichert, D., Bailey, J., Olieric, V., Wang, M., Caffrey, M.
Deposit date:2017-02-15
Release date:2017-07-12
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis.
Nat Commun, 8, 2017
5N6M
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STRUCTURE OF THE MEMBRANE INTEGRAL LIPOPROTEIN N-ACYLTRANSFERASE LNT FROM P. AERUGINOSA
Descriptor:Apolipoprotein N-acyltransferase, GLYCEROL, CITRATE ANION, ...
Authors:Huang, C.-Y., Boland, C., Howe, N., Wiktor, M., Vogeley, L., Weichert, D., Bailey, J., Olieric, V., Wang, M., Caffrey, M.
Deposit date:2017-02-15
Release date:2017-07-12
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis.
Nat Commun, 8, 2017
4BRR
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CRYSTAL STRUCTURE OF THE INTEGRAL MEMBRANE DIACYLGLYCEROL KINASE - DELTA 7.79
Descriptor:DIACYLGLYCEROL KINASE, (2R)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, ZINC ION, ...
Authors:Li, D., Howe, N., Caffrey, M.
Deposit date:2013-06-05
Release date:2014-06-18
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Crystal Structure of an Integral Membrane Enzyme Determined by X-Ray Free Electron Laser Femtocrystallography
To be Published
4O9R
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HUMAN SMOOTHENED RECEPTOR STRUCTURE IN COMPLEX WITH CYCLOPAMINE
Descriptor:Smoothened homolog/Soluble cytochrome b562 chimeric protein, Cyclopamine
Authors:Wang, C., Weierstall, U., James, D., White, T.A., Wang, D., Liu, W., Spence, J.C.H., Doak, R.B., Nelson, G., Fromme, P., Fromme, R., Grotjohann, I., Kupitz, C., Zatsepin, N.A., Liu, H., Basu, S., Wacker, D., Han, G.W., Katritch, V., Boutet, S., Messerschmidt, M., Willams, G.J., Koglin, J.E., Seibert, M.M., Klinker, M., Gati, C., Shoeman, R.L., Barty, A., Chapman, H.N., Kirian, R.A., Beyerlein, K.R., Stevens, R.C., Li, D., Shah, S.T.A., Howe, N., Caffrey, M., Cherezov, V., GPCR Network (GPCR)
Deposit date:2014-01-02
Release date:2014-03-05
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (3.204 Å)
Cite:Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography.
Nat Commun, 5, 2014
4UXZ
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STRUCTURE OF DELTA7-DGKA-SYN IN 7.9 MAG TO 2.18 ANGSTROM RESOLUTION
Descriptor:DIACYLGLYCEROL KINASE-DELTA 7, (2S)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, (2R)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, ...
Authors:Li, D., Howe, N., Caffrey, M.
Deposit date:2014-08-27
Release date:2015-09-30
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Ternary Structure Reveals Mechanism of a Membrane Diacylglycerol Kinase.
Nat.Commun., 6, 2015
4UYO
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STRUCTURE OF DELTA7-DGKA IN 7.9 MAG BY SERIAL FEMTOSECOND CRYSTATALLOGRAPHY TO 2.18 ANGSTROM RESOLUTION
Descriptor:DIACYLGLYCEROL KINASE-DELTA 7, (2S)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, (2R)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, ...
Authors:Li, D., Howe, N., Other, O., Caffrey, M.
Deposit date:2014-09-02
Release date:2015-09-30
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Ternary Structure Reveals Mechanism of a Membrane Diacylglycerol Kinase.
Nat.Commun., 6, 2015
4WAB
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CRYSTAL STRUCTURE OF MPGES1 SOLVED BY NATIVE-SAD PHASING
Descriptor:Prostaglandin E synthase,Leukotriene C4 synthase, GLUTATHIONE, 2-[[2,6-bis(chloranyl)-3-[(2,2-dimethylpropanoylamino)methyl]phenyl]amino]-1-methyl-6-(2-methyl-2-oxidanyl-propoxy)-N-[2,2,2-tris(fluoranyl)ethyl]benzimidazole-5-carboxamide
Authors:Weinert, T., Li, D., Howe, N., Caffrey, M., Wang, M.
Deposit date:2014-08-29
Release date:2014-12-10
Last modified:2015-02-11
Method:X-RAY DIFFRACTION (2.704 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
5D56
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IN MESO IN SITU SERIAL X-RAY CRYSTALLOGRAPHY STRUCTURE OF DIACYLGLYCEROL KINASE, DGKA, AT 100 K
Descriptor:Diacylglycerol kinase, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ZINC ION, ...
Authors:Huang, C.-Y., Howe, N., Olieric, V., Warshamanage, R., Diederichs, K., Wang, M., Caffrey, M.
Deposit date:2015-08-10
Release date:2016-01-13
Last modified:2016-03-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:In meso in situ serial X-ray crystallography of soluble and membrane proteins at cryogenic temperatures.
Acta Crystallogr D Struct Biol, 72, 2016
5D57
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IN MESO X-RAY CRYSTALLOGRAPHY STRUCTURE OF DIACYLGLYCEROL KINASE, DGKA, AT 100 K
Descriptor:Diacylglycerol kinase, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE
Authors:Huang, C.-Y., Howe, N., Olieric, V., Wang, M., Caffrey, M.
Deposit date:2015-08-10
Release date:2016-01-13
Last modified:2016-03-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:In meso in situ serial X-ray crystallography of soluble and membrane proteins at cryogenic temperatures.
Acta Crystallogr D Struct Biol, 72, 2016
5JKI
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CRYSTAL STRUCTURE OF THE FIRST TRANSMEMBRANE PAP2 TYPE PHOSPHATIDYLGLYCEROLPHOSPHATE PHOSPHATASE FROM BACILLUS SUBTILIS
Descriptor:Putative lipid phosphate phosphatase YodM, TUNGSTATE(VI)ION, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ...
Authors:El Ghachi, M., Howe, N., Lampion, A., Delbrassine, F., Vogeley, L., Caffrey, M., Sauvage, E., Auger, R., Guiseppe, A., Roure, S., Perlier, S., Mengin-lecreulx, D., Foglino, M., Touze, T.
Deposit date:2016-04-26
Release date:2017-02-22
Last modified:2017-05-24
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure and biochemical characterization of the transmembrane PAP2 type phosphatidylglycerol phosphate phosphatase from Bacillus subtilis.
Cell. Mol. Life Sci., 74, 2017
5OON
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STRUCTURE OF UNDECAPRENYL-PYROPHOSPHATE PHOSPHATASE, BACA
Descriptor:Undecaprenyl-diphosphatase, MERCURY (II) ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Huang, C.-Y., Olieric, V., Warshamanage, R., Wang, M., Howe, N., Ghachi, M.E.I., Weichert, D., Kerff, F., Stansfeld, P., Touze, T., Caffrey, M.
Deposit date:2017-08-08
Release date:2018-03-21
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of undecaprenyl-pyrophosphate phosphatase and its role in peptidoglycan biosynthesis.
Nat Commun, 9, 2018
6FMR
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IMISX-EP OF SE-PEPTST
Descriptor:Di-or tripeptide:H+ symporter, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, PHOSPHATE ION
Authors:Huang, C.-Y., Olieric, V., Howe, N., Warshamanage, R., Weinert, T., Panepucci, E., Vogeley, L., Basu, S., Diederichs, K., Caffrey, M., Wang, M.
Deposit date:2018-02-02
Release date:2018-08-29
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:In situ serial crystallography for rapid de novo membrane protein structure determination.
Commun Biol, 1, 2018
6FMS
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IMISX-EP OF SE-LSPA
Descriptor:Lipoprotein signal peptidase, N-METHYLLEUCINE, ISO-ISOLEUCINE, ...
Authors:Huang, C.-Y., Olieric, V., Howe, N., Warshamanage, R., Weinert, T., Panepucci, E., Vogeley, L., Basu, S., Diederichs, K., Caffrey, M., Wang, M.
Deposit date:2018-02-02
Release date:2018-08-29
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:In situ serial crystallography for rapid de novo membrane protein structure determination.
Commun Biol, 1, 2018
6FMT
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IMISX-EP OF HG-BACA SOAKING SAD
Descriptor:Undecaprenyl-diphosphatase, MERCURY (II) ION, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ...
Authors:Huang, C.-Y., Olieric, V., Howe, N., Warshamanage, R., Weinert, T., Panepucci, E., Vogeley, L., Basu, S., Diederichs, K., Caffrey, M., Wang, M.
Deposit date:2018-02-02
Release date:2018-09-05
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:In situ serial crystallography for rapid de novo membrane protein structure determination.
Commun Biol, 1, 2018
6FMV
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IMISX-EP OF HG-BACA SOAKING SIRAS
Descriptor:Undecaprenyl-diphosphatase, CITRATE ANION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Huang, C.-Y., Olieric, V., Howe, N., Warshamanage, R., Weinert, T., Panepucci, E., Vogeley, L., Basu, S., Diederichs, K., Caffrey, M., Wang, M.
Deposit date:2018-02-02
Release date:2018-09-05
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:In situ serial crystallography for rapid de novo membrane protein structure determination.
Commun Biol, 1, 2018
6FMW
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IMISX-EP OF HG-BACA COCRYSTALLIZATION
Descriptor:Undecaprenyl-diphosphatase, MERCURY (II) ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Huang, C.-Y., Olieric, V., Howe, N., Warshamanage, R., Weinert, T., Panepucci, E., Vogeley, L., Basu, S., Diederichs, K., Caffrey, M., Wang, M.
Deposit date:2018-02-02
Release date:2018-09-05
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:In situ serial crystallography for rapid de novo membrane protein structure determination.
Commun Biol, 1, 2018
6FMX
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IMISX-EP OF W-PGPB
Descriptor:Phosphatidylglycerophosphatase B, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, TUNGSTATE(VI)ION
Authors:Huang, C.-Y., Olieric, V., Howe, N., Warshamanage, R., Weinert, T., Panepucci, E., Vogeley, L., Basu, S., Diederichs, K., Caffrey, M., Wang, M.
Deposit date:2018-02-02
Release date:2018-09-05
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:In situ serial crystallography for rapid de novo membrane protein structure determination.
Commun Biol, 1, 2018
6FMY
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IMISX-EP OF S-PEPTST
Descriptor:Di-or tripeptide:H+ symporter, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ...
Authors:Huang, C.-Y., Olieric, V., Howe, N., Warshamanage, R., Weinert, T., Panepucci, E., Vogeley, L., Basu, S., Diederichs, K., Caffrey, M., Wang, M.
Deposit date:2018-02-02
Release date:2018-09-05
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:In situ serial crystallography for rapid de novo membrane protein structure determination.
Commun Biol, 1, 2018
4BPM
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CRYSTAL STRUCTURE OF A HUMAN INTEGRAL MEMBRANE ENZYME
Descriptor:PROSTAGLANDIN E SYNTHASE, FUSION PEPTIDE, GLUTATHIONE, ...
Authors:Li, D., Wang, M., Olieric, V., Caffrey, M.
Deposit date:2013-05-27
Release date:2014-04-16
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Crystallizing Membrane Proteins in the Lipidic Mesophase. Experience with Human Prostaglandin E2 Synthase 1 and an Evolving Strategy.
Cryst.Growth Des., 14, 2014
4PGO
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CRYSTAL STRUCTURE OF HYPOTHETICAL PROTEIN PF0907 FROM PYROCOCCUS FURIOSUS SOLVED BY SULFUR SAD USING SWISS LIGHT SOURCE DATA
Descriptor:Uncharacterized protein, CHLORIDE ION
Authors:Weinert, T., Waltersperger, S., Olieric, V., Panepucci, E., Chen, L., Rose, J.P., Wang, M., Wang, B.C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2014-05-02
Release date:2014-12-10
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
4PII
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CRYSTAL STRUCTURE OF HYPOTHETICAL PROTEIN PF0907 FROM PYROCOCCUS FURIOSUS SOLVED BY SULFUR SAD USING SWISS LIGHT SOURCE DATA
Descriptor:N-glycosylase/DNA lyase, CHLORIDE ION, IMIDAZOLE
Authors:Weinert, T., Waltersperger, S., Olieric, V., Panepucci, E., Chen, L., Rose, J.P., Wang, M., Wang, B.C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2014-05-08
Release date:2014-12-10
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
4R8T
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STRUCTURE OF JEV PROTEASE
Descriptor:Serine protease subunit NS2B, NS3, CHLORIDE ION
Authors:Nair, D.T., Weinert, T., Wang, M., Olieric, V.
Deposit date:2014-09-03
Release date:2014-12-24
Last modified:2015-08-12
Method:X-RAY DIFFRACTION (2.133 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
4R8U
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S-SAD STRUCTURE OF DINB-DNA COMPLEX
Descriptor:DNA polymerase IV, DNA, MAGNESIUM ION, ...
Authors:Kottur, J., Nair, D.T., Weinert, T., Oligeric, V., Wang, M.
Deposit date:2014-09-03
Release date:2015-01-14
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination
Nat.Methods, 12, 2015
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