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6QG0
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STRUCTURE OF EIF2B-EIF2 (PHOSPHORYLATED AT SER51) COMPLEX (MODEL 1)
Descriptor:Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit gamma, ...
Authors:Llacer, J.L., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG1
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STRUCTURE OF EIF2B-EIF2 (PHOSPHORYLATED AT SER51) COMPLEX (MODEL 2)
Descriptor:Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit gamma, ...
Authors:Llacer, J.L., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG2
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STRUCTURE OF EIF2B-EIF2 (PHOSPHORYLATED AT SER51) COMPLEX (MODEL A)
Descriptor:Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit gamma, ...
Authors:Llacer, J.L., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG3
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STRUCTURE OF EIF2B-EIF2 (PHOSPHORYLATED AT SER51) COMPLEX (MODEL B)
Descriptor:Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit gamma, ...
Authors:Llacer, J.L., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Method:ELECTRON MICROSCOPY (9.4 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG5
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STRUCTURE OF EIF2B-EIF2 (PHOSPHORYLATED AT SER51) COMPLEX (MODEL C)
Descriptor:Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit gamma, ...
Authors:Llacer, J.L., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Method:ELECTRON MICROSCOPY (10.1 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG6
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STRUCTURE OF EIF2B-EIF2 (PHOSPHORYLATED AT SER51) COMPLEX (MODEL D)
Descriptor:Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit gamma, ...
Authors:Llacer, J.L., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Method:ELECTRON MICROSCOPY (4.65 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
3D36
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HOW TO SWITCH OFF A HISTIDINE KINASE: CRYSTAL STRUCTURE OF GEOBACILLUS STEAROTHERMOPHILUS KINB WITH THE INHIBITOR SDA
Descriptor:Sporulation kinase B, Sporulation kinase inhibitor Sda, MAGNESIUM ION, ...
Authors:Bick, M.J., Lamour, V., Rajashankar, K.R., Gordiyenko, Y., Robinson, C.V., Darst, S.A.
Deposit date:2008-05-09
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:How to switch off a histidine kinase: crystal structure of Geobacillus stearothermophilus KinB with the inhibitor Sda
J.Mol.Biol., 386, 2009
4BKX
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THE STRUCTURE OF HDAC1 IN COMPLEX WITH THE DIMERIC ELM2-SANT DOMAIN OF MTA1 FROM THE NURD COMPLEX
Descriptor:METASTASIS-ASSOCIATED PROTEIN MTA1, HISTONE DEACETYLASE 1, ZINC ION, ...
Authors:Millard, C.J., Watson, P.J., Celardo, I., Gordiyenko, Y., Cowley, S.M., Robinson, C.V., Fairall, L., Schwabe, J.W.R.
Deposit date:2013-04-30
Release date:2013-07-03
Last modified:2013-07-31
Method:X-RAY DIFFRACTION (3 Å)
Cite:Class I Hdacs Share a Common Mechanism of Regulation by Inositol Phosphates.
Mol.Cell, 51, 2013
4CYI
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CHAETOMIUM THERMOPHILUM PAN3
Descriptor:PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN3-LIKE PROTEIN, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN3-L PROTEIN, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Wolf, J., Valkov, E., Allen, M.D., Meineke, B., Gordiyenko, Y., McLaughlin, S.H., Olsen, T.M., Robinson, C.V., Bycroft, M., Stewart, M., Passmore, L.A.
Deposit date:2014-04-11
Release date:2014-06-11
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural Basis for Pan3 Binding to Pan2 and its Function in Mrna Recruitment and Deadenylation
Embo J., 33, 2014
4CYJ
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CHAETOMIUM THERMOPHILUM PAN2:PAN3 COMPLEX
Descriptor:PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN3-LIKE PROTEIN, PAN2, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Wolf, J., Valkov, E., Allen, M.D., Meineke, B., Gordiyenko, Y., McLaughlin, S.H., Olsen, T.M., Robinson, C.V., Bycroft, M., Stewart, M., Passmore, L.A.
Deposit date:2014-04-11
Release date:2014-06-11
Last modified:2014-07-30
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structural Basis for Pan3 Binding to Pan2 and its Function in Mrna Recruitment and Deadenylation
Embo J., 33, 2014
4CYK
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STRUCTURAL BASIS FOR BINDING OF PAN3 TO PAN2 AND ITS FUNCTION IN MRNA RECRUITMENT AND DEADENYLATION
Descriptor:PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN3, ZINC ION
Authors:Wolf, J., Valkov, E., Allen, M.D., Meineke, B., Gordiyenko, Y., McLaughlin, S.H., Olsen, T.M., Robinson, C.V., Bycroft, M., Stewart, M., Passmore, L.A.
Deposit date:2014-04-11
Release date:2014-05-21
Last modified:2016-04-27
Method:SOLUTION NMR
Cite:Structural Basis for Pan3 Binding to Pan2 and its Function in Mrna Recruitment and Deadenylation.
Embo J., 33, 2014
5IQR
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STRUCTURE OF RELA BOUND TO THE 70S RIBOSOME
Descriptor:50S ribosomal protein L2, 50S ribosomal protein L3, 50S ribosomal protein L4, ...
Authors:Brown, A., Fernandez, I.S., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2016-03-11
Release date:2016-05-04
Last modified:2018-10-17
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Ribosome-dependent activation of stringent control.
Nature, 534, 2016
5MDV
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STRUCTURE OF ARFA AND RF2 BOUND TO THE 70S RIBOSOME (ACCOMMODATED STATE)
Descriptor:23S ribosomal RNA, 16S ribosomal RNA, 5S ribosomal RNA, ...
Authors:James, N.R., Brown, A., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2016-11-13
Release date:2016-12-14
Last modified:2018-10-17
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Translational termination without a stop codon.
Science, 354, 2016
5MDW
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STRUCTURE OF ARFA(A18T) AND RF2 BOUND TO THE 70S RIBOSOME (PRE-ACCOMMODATED STATE)
Descriptor:23S ribosomal RNA, 16S ribosomal RNA, 5S ribosomal RNA, ...
Authors:James, N.R., Brown, A., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2016-11-13
Release date:2016-12-14
Last modified:2018-10-17
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Translational termination without a stop codon.
Science, 354, 2016
5MDY
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STRUCTURE OF ARFA AND TTRF2 BOUND TO THE 70S RIBOSOME (PRE-ACCOMMODATED STATE)
Descriptor:23S ribosomal RNA, 16S ribosomal RNA, 5S ribosomal RNA, ...
Authors:James, N.R., Brown, A., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2016-11-13
Release date:2016-12-21
Last modified:2018-10-17
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Translational termination without a stop codon.
Science, 354, 2016
5MDZ
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STRUCTURE OF THE 70S RIBOSOME (EMPTY A SITE)
Descriptor:23S ribosomal RNA, 16S ribosomal RNA, 5S ribosomal RNA, ...
Authors:James, N.R., Brown, A., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2016-11-13
Release date:2016-12-14
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Translational termination without a stop codon.
Science, 354, 2016
6FYX
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STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX WITH EIF5 N-TERMINAL DOMAIN (MODEL C1)
Descriptor:tRNAi, 18S ribosomal RNA, mRNA (31-MER), ...
Authors:Llacer, J.L., Hussain, T., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2018-03-12
Release date:2018-12-05
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife, 7, 2018
6FYY
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STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX WITH EIF5 N-TERMINAL DOMAIN (MODEL C2)
Descriptor:tRNAi, 18S ribosomal RNA, mRNA (31-MER), ...
Authors:Llacer, J.L., Hussain, T., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2018-03-12
Release date:2018-12-05
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife, 7, 2018
5MU3
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CRYSTAL STRUCTURE OF CTF19-MCM21 KINETOCHORE ASSEMBLY BOUND WITH CTF19-MCM21 BINDING MOTIF OF CENTRAL KINETOCHORE SUBUNIT OKP1
Descriptor:Central kinetochore subunit MCM21, Central kinetochore subunit CTF19, Central kinetochore subunit Okp1
Authors:Schmitzberger, F.
Deposit date:2017-01-12
Release date:2017-11-01
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular basis for inner kinetochore configuration through RWD domain-peptide interactions.
EMBO J., 36, 2017
6EOJ
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POLYA POLYMERASE MODULE OF THE CLEAVAGE AND POLYADENYLATION FACTOR (CPF) FROM SACCHAROMYCES CEREVISIAE
Descriptor:Protein CFT1, mRNA 3'-end-processing protein YTH1, Polyadenylation factor subunit 2,Polyadenylation factor subunit 2, ...
Authors:Casanal, A., Kumar, A., Hill, C.H., Emsley, P., Passmore, L.
Deposit date:2017-10-09
Release date:2017-11-15
Last modified:2018-01-31
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Architecture of eukaryotic mRNA 3'-end processing machinery.
Science, 358, 2017
6GSN
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STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX IN CLOSED CONFORMATION
Descriptor:18S rRNA (1798-MER), KLLA0F09812p, KLLA0D08305p, ...
Authors:Llacer, J.L., Hussain, T., Ramakrishnan, V.
Deposit date:2018-06-14
Release date:2019-06-26
Method:ELECTRON MICROSCOPY (5.75 Å)
Cite:Towards a model of eIF3 on the 40S subunit interface in eukaryotic translation initiation
To Be Published
6Q95
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STRUCTURE OF TMRNA SMPB BOUND IN A SITE OF T. THERMOPHILUS 70S RIBOSOME
Descriptor:16S RIBOSOMAL RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Rae, C.D.
Deposit date:2018-12-17
Release date:2019-02-27
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:How a circularized tmRNA moves through the ribosome.
Science, 363, 2019
6Q97
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STRUCTURE OF TMRNA SMPB BOUND IN A SITE OF E. COLI 70S RIBOSOME
Descriptor:23S ribosomal RNA, 16S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Rae, C.D.
Deposit date:2018-12-17
Release date:2019-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:How a circularized tmRNA moves through the ribosome.
Science, 363, 2019
6Q98
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STRUCTURE OF TMRNA SMPB BOUND IN P SITE OF E. COLI 70S RIBOSOME
Descriptor:23S ribosomal RNA, 16S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Rae, C.D.
Deposit date:2018-12-17
Release date:2019-02-27
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:How a circularized tmRNA moves through the ribosome.
Science, 363, 2019
6Q9A
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STRUCTURE OF TMRNA SMPB BOUND PAST E SITE OF E. COLI 70S RIBOSOME
Descriptor:23S ribosomal RNA, 16S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Rae, C.D.
Deposit date:2018-12-17
Release date:2019-04-17
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:How a circularized tmRNA moves through the ribosome.
Science, 363, 2019
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