8OZ0
Structure of a human 48S translation initiation complex with eIF4F and eIF4A
This is a non-PDB format compatible entry.
Summary for 8OZ0
| Entry DOI | 10.2210/pdb8oz0/pdb |
| EMDB information | 17297 |
| Descriptor | Eukaryotic translation initiation factor 3 subunit E, Eukaryotic translation initiation factor 2 subunit 3, Eukaryotic translation initiation factor 3 subunit I, ... (58 entities in total) |
| Functional Keywords | translation, eif4a, eif4f, initiation, ribosome, mrna |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 57 |
| Total formula weight | 2476483.59 |
| Authors | Brito Querido, J.,Sokabe, M.,Diaz-Lopez, I.,Gordiyenko, Y.,Fraser, C.S.,Ramakrishnan, V. (deposition date: 2023-05-06, release date: 2024-02-07, Last modification date: 2024-04-24) |
| Primary citation | Brito Querido, J.,Sokabe, M.,Diaz-Lopez, I.,Gordiyenko, Y.,Fraser, C.S.,Ramakrishnan, V. The structure of a human translation initiation complex reveals two independent roles for the helicase eIF4A. Nat.Struct.Mol.Biol., 31:455-464, 2024 Cited by PubMed: 38287194DOI: 10.1038/s41594-023-01196-0 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.5 Å) |
Structure validation
Download full validation report
