8OZ0

Structure of a human 48S translation initiation complex with eIF4F and eIF4A

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0000166	molecular_function	nucleotide binding
1	0000339	molecular_function	RNA cap binding
1	0002183	biological_process	cytoplasmic translational initiation
1	0003676	molecular_function	nucleic acid binding
1	0003723	molecular_function	RNA binding
1	0003724	molecular_function	RNA helicase activity
1	0003725	molecular_function	double-stranded RNA binding
1	0003729	molecular_function	mRNA binding
1	0003743	molecular_function	translation initiation factor activity
1	0004386	molecular_function	helicase activity
1	0005515	molecular_function	protein binding
1	0005524	molecular_function	ATP binding
1	0005634	cellular_component	nucleus
1	0005737	cellular_component	cytoplasm
1	0005829	cellular_component	cytosol
1	0005886	cellular_component	plasma membrane
1	0006412	biological_process	translation
1	0006413	biological_process	translational initiation
1	0008135	molecular_function	translation factor activity, RNA binding
1	0010494	cellular_component	cytoplasmic stress granule
1	0016020	cellular_component	membrane
1	0016281	cellular_component	eukaryotic translation initiation factor 4F complex
1	0016787	molecular_function	hydrolase activity
1	0016887	molecular_function	ATP hydrolysis activity
1	0045944	biological_process	positive regulation of transcription by RNA polymerase II
1	0048471	cellular_component	perinuclear region of cytoplasm
1	0070062	cellular_component	extracellular exosome
1	0097165	cellular_component	nuclear stress granule
2	0003723	molecular_function	RNA binding
3	0000166	molecular_function	nucleotide binding
3	0000339	molecular_function	RNA cap binding
3	0002183	biological_process	cytoplasmic translational initiation
3	0003676	molecular_function	nucleic acid binding
3	0003723	molecular_function	RNA binding
3	0003724	molecular_function	RNA helicase activity
3	0003725	molecular_function	double-stranded RNA binding
3	0003729	molecular_function	mRNA binding
3	0003743	molecular_function	translation initiation factor activity
3	0004386	molecular_function	helicase activity
3	0005515	molecular_function	protein binding
3	0005524	molecular_function	ATP binding
3	0005634	cellular_component	nucleus
3	0005737	cellular_component	cytoplasm
3	0005829	cellular_component	cytosol
3	0005886	cellular_component	plasma membrane
3	0006412	biological_process	translation
3	0006413	biological_process	translational initiation
3	0008135	molecular_function	translation factor activity, RNA binding
3	0010494	cellular_component	cytoplasmic stress granule
3	0016020	cellular_component	membrane
3	0016281	cellular_component	eukaryotic translation initiation factor 4F complex
3	0016787	molecular_function	hydrolase activity
3	0016887	molecular_function	ATP hydrolysis activity
3	0045944	biological_process	positive regulation of transcription by RNA polymerase II
3	0048471	cellular_component	perinuclear region of cytoplasm
3	0070062	cellular_component	extracellular exosome
3	0097165	cellular_component	nuclear stress granule
5	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
5	0000785	cellular_component	chromatin
5	0001732	biological_process	formation of cytoplasmic translation initiation complex
5	0002183	biological_process	cytoplasmic translational initiation
5	0003723	molecular_function	RNA binding
5	0003743	molecular_function	translation initiation factor activity
5	0005515	molecular_function	protein binding
5	0005634	cellular_component	nucleus
5	0005654	cellular_component	nucleoplasm
5	0005737	cellular_component	cytoplasm
5	0005829	cellular_component	cytosol
5	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
5	0006412	biological_process	translation
5	0006413	biological_process	translational initiation
5	0006446	biological_process	regulation of translational initiation
5	0014069	cellular_component	postsynaptic density
5	0016020	cellular_component	membrane
5	0016282	cellular_component	eukaryotic 43S preinitiation complex
5	0016605	cellular_component	PML body
5	0032991	cellular_component	protein-containing complex
5	0033290	cellular_component	eukaryotic 48S preinitiation complex
5	0045296	molecular_function	cadherin binding
5	0045727	biological_process	positive regulation of translation
5	0045947	biological_process	negative regulation of translational initiation
5	0070062	cellular_component	extracellular exosome
5	0071540	cellular_component	eukaryotic translation initiation factor 3 complex, eIF3e
6	0001732	biological_process	formation of cytoplasmic translation initiation complex
6	0002183	biological_process	cytoplasmic translational initiation
6	0003743	molecular_function	translation initiation factor activity
6	0004843	molecular_function	cysteine-type deubiquitinase activity
6	0005515	molecular_function	protein binding
6	0005737	cellular_component	cytoplasm
6	0005829	cellular_component	cytosol
6	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
6	0006412	biological_process	translation
6	0006413	biological_process	translational initiation
6	0006508	biological_process	proteolysis
6	0008233	molecular_function	peptidase activity
6	0008234	molecular_function	cysteine-type peptidase activity
6	0008237	molecular_function	metallopeptidase activity
6	0016020	cellular_component	membrane
6	0016282	cellular_component	eukaryotic 43S preinitiation complex
6	0016787	molecular_function	hydrolase activity
6	0031369	molecular_function	translation initiation factor binding
6	0033290	cellular_component	eukaryotic 48S preinitiation complex
6	0042802	molecular_function	identical protein binding
6	0045202	cellular_component	synapse
6	0071541	cellular_component	eukaryotic translation initiation factor 3 complex, eIF3m
6	0075522	biological_process	IRES-dependent viral translational initiation
6	0101005	molecular_function	deubiquitinase activity
6	0140492	molecular_function	metal-dependent deubiquitinase activity
7	0001732	biological_process	formation of cytoplasmic translation initiation complex
7	0002183	biological_process	cytoplasmic translational initiation
7	0003676	molecular_function	nucleic acid binding
7	0003723	molecular_function	RNA binding
7	0003743	molecular_function	translation initiation factor activity
7	0005515	molecular_function	protein binding
7	0005634	cellular_component	nucleus
7	0005737	cellular_component	cytoplasm
7	0005829	cellular_component	cytosol
7	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
7	0006412	biological_process	translation
7	0006413	biological_process	translational initiation
7	0016282	cellular_component	eukaryotic 43S preinitiation complex
7	0033290	cellular_component	eukaryotic 48S preinitiation complex
7	0048471	cellular_component	perinuclear region of cytoplasm
7	0075525	biological_process	viral translational termination-reinitiation
8	0001732	biological_process	formation of cytoplasmic translation initiation complex
8	0002183	biological_process	cytoplasmic translational initiation
8	0003723	molecular_function	RNA binding
8	0003743	molecular_function	translation initiation factor activity
8	0005515	molecular_function	protein binding
8	0005737	cellular_component	cytoplasm
8	0005829	cellular_component	cytosol
8	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
8	0006412	biological_process	translation
8	0006413	biological_process	translational initiation
8	0006446	biological_process	regulation of translational initiation
8	0008233	molecular_function	peptidase activity
8	0008237	molecular_function	metallopeptidase activity
8	0016020	cellular_component	membrane
8	0016282	cellular_component	eukaryotic 43S preinitiation complex
8	0032435	biological_process	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
8	0033290	cellular_component	eukaryotic 48S preinitiation complex
8	0070062	cellular_component	extracellular exosome
8	0071541	cellular_component	eukaryotic translation initiation factor 3 complex, eIF3m
8	0140492	molecular_function	metal-dependent deubiquitinase activity
9	0002181	biological_process	cytoplasmic translation
9	0003723	molecular_function	RNA binding
9	0003730	molecular_function	mRNA 3'-UTR binding
9	0003735	molecular_function	structural constituent of ribosome
9	0005515	molecular_function	protein binding
9	0005737	cellular_component	cytoplasm
9	0005783	cellular_component	endoplasmic reticulum
9	0005829	cellular_component	cytosol
9	0005840	cellular_component	ribosome
9	0006412	biological_process	translation
9	0022625	cellular_component	cytosolic large ribosomal subunit
9	0048027	molecular_function	mRNA 5'-UTR binding
9	1990904	cellular_component	ribonucleoprotein complex
A	0001732	biological_process	formation of cytoplasmic translation initiation complex
A	0002183	biological_process	cytoplasmic translational initiation
A	0002188	biological_process	translation reinitiation
A	0003723	molecular_function	RNA binding
A	0003729	molecular_function	mRNA binding
A	0003743	molecular_function	translation initiation factor activity
A	0005198	molecular_function	structural molecule activity
A	0005515	molecular_function	protein binding
A	0005654	cellular_component	nucleoplasm
A	0005730	cellular_component	nucleolus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
A	0005874	cellular_component	microtubule
A	0006412	biological_process	translation
A	0006413	biological_process	translational initiation
A	0014069	cellular_component	postsynaptic density
A	0016020	cellular_component	membrane
A	0016282	cellular_component	eukaryotic 43S preinitiation complex
A	0030971	molecular_function	receptor tyrosine kinase binding
A	0032991	cellular_component	protein-containing complex
A	0033290	cellular_component	eukaryotic 48S preinitiation complex
A	0043226	cellular_component	organelle
A	0043614	cellular_component	multi-eIF complex
A	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
A	0071540	cellular_component	eukaryotic translation initiation factor 3 complex, eIF3e
A	0071541	cellular_component	eukaryotic translation initiation factor 3 complex, eIF3m
A	0075522	biological_process	IRES-dependent viral translational initiation
A	0075525	biological_process	viral translational termination-reinitiation
B	0001732	biological_process	formation of cytoplasmic translation initiation complex
B	0002183	biological_process	cytoplasmic translational initiation
B	0003723	molecular_function	RNA binding
B	0003743	molecular_function	translation initiation factor activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
B	0006412	biological_process	translation
B	0006413	biological_process	translational initiation
B	0006446	biological_process	regulation of translational initiation
B	0016020	cellular_component	membrane
B	0016282	cellular_component	eukaryotic 43S preinitiation complex
B	0033290	cellular_component	eukaryotic 48S preinitiation complex
B	0043022	molecular_function	ribosome binding
C	0001732	biological_process	formation of cytoplasmic translation initiation complex
C	0002183	biological_process	cytoplasmic translational initiation
C	0003743	molecular_function	translation initiation factor activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
C	0006412	biological_process	translation
C	0006413	biological_process	translational initiation
C	0016282	cellular_component	eukaryotic 43S preinitiation complex
C	0031369	molecular_function	translation initiation factor binding
C	0032991	cellular_component	protein-containing complex
C	0033290	cellular_component	eukaryotic 48S preinitiation complex
C	0071541	cellular_component	eukaryotic translation initiation factor 3 complex, eIF3m
D	0000423	biological_process	mitophagy
D	0003676	molecular_function	nucleic acid binding
D	0003723	molecular_function	RNA binding
D	0003743	molecular_function	translation initiation factor activity
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005829	cellular_component	cytosol
D	0005850	cellular_component	eukaryotic translation initiation factor 2 complex
D	0006412	biological_process	translation
D	0006413	biological_process	translational initiation
D	0006417	biological_process	regulation of translation
D	0010494	cellular_component	cytoplasmic stress granule
D	0016020	cellular_component	membrane
D	0032057	biological_process	negative regulation of translational initiation in response to stress
D	0033290	cellular_component	eukaryotic 48S preinitiation complex
D	0034063	biological_process	stress granule assembly
D	0034198	biological_process	cellular response to amino acid starvation
D	0034599	biological_process	cellular response to oxidative stress
D	0034605	biological_process	cellular response to heat
D	0034644	biological_process	cellular response to UV
D	0034976	biological_process	response to endoplasmic reticulum stress
D	0036490	biological_process	regulation of translation in response to endoplasmic reticulum stress
D	0036499	biological_process	PERK-mediated unfolded protein response
D	0043022	molecular_function	ribosome binding
D	0043558	biological_process	regulation of translational initiation in response to stress
D	0044207	cellular_component	translation initiation ternary complex
D	0045202	cellular_component	synapse
D	0070062	cellular_component	extracellular exosome
D	0097250	biological_process	mitochondrial respirasome assembly
D	0097451	cellular_component	glial limiting end-foot
D	0140468	biological_process	HRI-mediated signaling
D	1904373	biological_process	response to kainic acid
D	1990737	biological_process	response to manganese-induced endoplasmic reticulum stress
D	2000676	biological_process	positive regulation of type B pancreatic cell apoptotic process
E	0000049	molecular_function	tRNA binding
E	0000166	molecular_function	nucleotide binding
E	0001731	biological_process	formation of translation preinitiation complex
E	0002183	biological_process	cytoplasmic translational initiation
E	0003743	molecular_function	translation initiation factor activity
E	0003924	molecular_function	GTPase activity
E	0005515	molecular_function	protein binding
E	0005525	molecular_function	GTP binding
E	0005634	cellular_component	nucleus
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005850	cellular_component	eukaryotic translation initiation factor 2 complex
E	0006412	biological_process	translation
E	0006413	biological_process	translational initiation
E	0008135	molecular_function	translation factor activity, RNA binding
E	0016787	molecular_function	hydrolase activity
E	0045296	molecular_function	cadherin binding
E	0070062	cellular_component	extracellular exosome
E	1990856	molecular_function	methionyl-initiator methionine tRNA binding
F	0001732	biological_process	formation of cytoplasmic translation initiation complex
F	0002183	biological_process	cytoplasmic translational initiation
F	0003723	molecular_function	RNA binding
F	0003743	molecular_function	translation initiation factor activity
F	0005515	molecular_function	protein binding
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
F	0006412	biological_process	translation
F	0006413	biological_process	translational initiation
F	0016282	cellular_component	eukaryotic 43S preinitiation complex
F	0033290	cellular_component	eukaryotic 48S preinitiation complex
F	0045202	cellular_component	synapse
F	0070062	cellular_component	extracellular exosome
F	0071541	cellular_component	eukaryotic translation initiation factor 3 complex, eIF3m
G	0000049	molecular_function	tRNA binding
G	0003723	molecular_function	RNA binding
G	0003743	molecular_function	translation initiation factor activity
G	0005515	molecular_function	protein binding
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006412	biological_process	translation
G	0006413	biological_process	translational initiation
G	0008135	molecular_function	translation factor activity, RNA binding
G	0016282	cellular_component	eukaryotic 43S preinitiation complex
G	0033290	cellular_component	eukaryotic 48S preinitiation complex
G	0042255	biological_process	ribosome assembly
G	0043614	cellular_component	multi-eIF complex
G	0045202	cellular_component	synapse
H	0000166	molecular_function	nucleotide binding
H	0001732	biological_process	formation of cytoplasmic translation initiation complex
H	0003723	molecular_function	RNA binding
H	0003743	molecular_function	translation initiation factor activity
H	0005092	molecular_function	GDP-dissociation inhibitor activity
H	0005096	molecular_function	GTPase activator activity
H	0005515	molecular_function	protein binding
H	0005525	molecular_function	GTP binding
H	0005634	cellular_component	nucleus
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0005886	cellular_component	plasma membrane
H	0006412	biological_process	translation
H	0006413	biological_process	translational initiation
H	0006446	biological_process	regulation of translational initiation
H	0042255	biological_process	ribosome assembly
H	0045202	cellular_component	synapse
H	0045296	molecular_function	cadherin binding
H	0071074	molecular_function	eukaryotic initiation factor eIF2 binding
I	0001732	biological_process	formation of cytoplasmic translation initiation complex
I	0002183	biological_process	cytoplasmic translational initiation
I	0003676	molecular_function	nucleic acid binding
I	0003723	molecular_function	RNA binding
I	0003743	molecular_function	translation initiation factor activity
I	0005515	molecular_function	protein binding
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
I	0006412	biological_process	translation
I	0006413	biological_process	translational initiation
I	0006446	biological_process	regulation of translational initiation
I	0010494	cellular_component	cytoplasmic stress granule
I	0016282	cellular_component	eukaryotic 43S preinitiation complex
I	0031369	molecular_function	translation initiation factor binding
I	0033290	cellular_component	eukaryotic 48S preinitiation complex
I	0045202	cellular_component	synapse
I	0060090	molecular_function	molecular adaptor activity
I	0070062	cellular_component	extracellular exosome
I	0071541	cellular_component	eukaryotic translation initiation factor 3 complex, eIF3m
I	0075522	biological_process	IRES-dependent viral translational initiation
I	0075525	biological_process	viral translational termination-reinitiation
J	0001732	biological_process	formation of cytoplasmic translation initiation complex
J	0002183	biological_process	cytoplasmic translational initiation
J	0003723	molecular_function	RNA binding
J	0003743	molecular_function	translation initiation factor activity
J	0005515	molecular_function	protein binding
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
J	0006412	biological_process	translation
J	0006413	biological_process	translational initiation
J	0016282	cellular_component	eukaryotic 43S preinitiation complex
J	0031369	molecular_function	translation initiation factor binding
J	0033290	cellular_component	eukaryotic 48S preinitiation complex
J	0043022	molecular_function	ribosome binding
J	0045727	biological_process	positive regulation of translation
K	0001650	cellular_component	fibrillar center
K	0001732	biological_process	formation of cytoplasmic translation initiation complex
K	0002183	biological_process	cytoplasmic translational initiation
K	0003723	molecular_function	RNA binding
K	0003743	molecular_function	translation initiation factor activity
K	0005515	molecular_function	protein binding
K	0005654	cellular_component	nucleoplasm
K	0005730	cellular_component	nucleolus
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
K	0006412	biological_process	translation
K	0006413	biological_process	translational initiation
K	0016020	cellular_component	membrane
K	0016282	cellular_component	eukaryotic 43S preinitiation complex
K	0032991	cellular_component	protein-containing complex
K	0033290	cellular_component	eukaryotic 48S preinitiation complex
K	0045202	cellular_component	synapse
K	0075525	biological_process	viral translational termination-reinitiation
L	0001843	biological_process	neural tube closure
L	0002181	biological_process	cytoplasmic translation
L	0003723	molecular_function	RNA binding
L	0003730	molecular_function	mRNA 3'-UTR binding
L	0003735	molecular_function	structural constituent of ribosome
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005730	cellular_component	nucleolus
L	0005737	cellular_component	cytoplasm
L	0005783	cellular_component	endoplasmic reticulum
L	0005813	cellular_component	centrosome
L	0005829	cellular_component	cytosol
L	0005840	cellular_component	ribosome
L	0005856	cellular_component	cytoskeleton
L	0005925	cellular_component	focal adhesion
L	0006364	biological_process	rRNA processing
L	0006412	biological_process	translation
L	0010628	biological_process	positive regulation of gene expression
L	0014033	biological_process	neural crest cell differentiation
L	0016020	cellular_component	membrane
L	0019901	molecular_function	protein kinase binding
L	0022626	cellular_component	cytosolic ribosome
L	0022627	cellular_component	cytosolic small ribosomal subunit
L	0032040	cellular_component	small-subunit processome
L	0032991	cellular_component	protein-containing complex
L	0042274	biological_process	ribosomal small subunit biogenesis
L	0045202	cellular_component	synapse
L	0048027	molecular_function	mRNA 5'-UTR binding
L	0050821	biological_process	protein stabilization
L	1902255	biological_process	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
L	1904667	biological_process	negative regulation of ubiquitin protein ligase activity
L	1990904	cellular_component	ribonucleoprotein complex
L	1990948	molecular_function	ubiquitin ligase inhibitor activity
L	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
M	0000028	biological_process	ribosomal small subunit assembly
M	0002181	biological_process	cytoplasmic translation
M	0003677	molecular_function	DNA binding
M	0003723	molecular_function	RNA binding
M	0003735	molecular_function	structural constituent of ribosome
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0005654	cellular_component	nucleoplasm
M	0005730	cellular_component	nucleolus
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0005840	cellular_component	ribosome
M	0006364	biological_process	rRNA processing
M	0006412	biological_process	translation
M	0008270	molecular_function	zinc ion binding
M	0014069	cellular_component	postsynaptic density
M	0022626	cellular_component	cytosolic ribosome
M	0022627	cellular_component	cytosolic small ribosomal subunit
M	0032040	cellular_component	small-subunit processome
M	0042274	biological_process	ribosomal small subunit biogenesis
M	0046872	molecular_function	metal ion binding
M	0098793	cellular_component	presynapse
M	0098978	cellular_component	glutamatergic synapse
M	0098982	cellular_component	GABA-ergic synapse
M	1990904	cellular_component	ribonucleoprotein complex
N	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
N	0000461	biological_process	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
N	0002181	biological_process	cytoplasmic translation
N	0003723	molecular_function	RNA binding
N	0003735	molecular_function	structural constituent of ribosome
N	0005515	molecular_function	protein binding
N	0005654	cellular_component	nucleoplasm
N	0005737	cellular_component	cytoplasm
N	0005783	cellular_component	endoplasmic reticulum
N	0005791	cellular_component	rough endoplasmic reticulum
N	0005829	cellular_component	cytosol
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
N	0015935	cellular_component	small ribosomal subunit
N	0022626	cellular_component	cytosolic ribosome
N	0022627	cellular_component	cytosolic small ribosomal subunit
N	0045202	cellular_component	synapse
N	1990904	cellular_component	ribonucleoprotein complex
O	0002181	biological_process	cytoplasmic translation
O	0003723	molecular_function	RNA binding
O	0003729	molecular_function	mRNA binding
O	0003735	molecular_function	structural constituent of ribosome
O	0005515	molecular_function	protein binding
O	0005634	cellular_component	nucleus
O	0005654	cellular_component	nucleoplasm
O	0005730	cellular_component	nucleolus
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0005840	cellular_component	ribosome
O	0005925	cellular_component	focal adhesion
O	0006412	biological_process	translation
O	0015935	cellular_component	small ribosomal subunit
O	0016020	cellular_component	membrane
O	0017134	molecular_function	fibroblast growth factor binding
O	0019899	molecular_function	enzyme binding
O	0022626	cellular_component	cytosolic ribosome
O	0022627	cellular_component	cytosolic small ribosomal subunit
O	0045296	molecular_function	cadherin binding
O	0051443	biological_process	positive regulation of ubiquitin-protein transferase activity
O	0070062	cellular_component	extracellular exosome
O	1990904	cellular_component	ribonucleoprotein complex
P	0002181	biological_process	cytoplasmic translation
P	0003723	molecular_function	RNA binding
P	0003735	molecular_function	structural constituent of ribosome
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005654	cellular_component	nucleoplasm
P	0005730	cellular_component	nucleolus
P	0005737	cellular_component	cytoplasm
P	0005783	cellular_component	endoplasmic reticulum
P	0005829	cellular_component	cytosol
P	0005840	cellular_component	ribosome
P	0005925	cellular_component	focal adhesion
P	0006412	biological_process	translation
P	0006413	biological_process	translational initiation
P	0022626	cellular_component	cytosolic ribosome
P	0022627	cellular_component	cytosolic small ribosomal subunit
P	0030154	biological_process	cell differentiation
P	0032040	cellular_component	small-subunit processome
P	0042274	biological_process	ribosomal small subunit biogenesis
P	0043066	biological_process	negative regulation of apoptotic process
P	0045202	cellular_component	synapse
P	0048027	molecular_function	mRNA 5'-UTR binding
P	0070062	cellular_component	extracellular exosome
P	1990904	cellular_component	ribonucleoprotein complex
Q	0000028	biological_process	ribosomal small subunit assembly
Q	0001618	molecular_function	virus receptor activity
Q	0002181	biological_process	cytoplasmic translation
Q	0003677	molecular_function	DNA binding
Q	0003723	molecular_function	RNA binding
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005055	molecular_function	laminin receptor activity
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005654	cellular_component	nucleoplasm
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0005840	cellular_component	ribosome
Q	0005886	cellular_component	plasma membrane
Q	0006338	biological_process	chromatin remodeling
Q	0006412	biological_process	translation
Q	0007155	biological_process	cell adhesion
Q	0015935	cellular_component	small ribosomal subunit
Q	0016020	cellular_component	membrane
Q	0022626	cellular_component	cytosolic ribosome
Q	0022627	cellular_component	cytosolic small ribosomal subunit
Q	0043022	molecular_function	ribosome binding
Q	0043236	molecular_function	laminin binding
Q	0046718	biological_process	symbiont entry into host cell
Q	0070062	cellular_component	extracellular exosome
Q	0140374	biological_process	antiviral innate immune response
Q	1990904	cellular_component	ribonucleoprotein complex
R	0002181	biological_process	cytoplasmic translation
R	0003723	molecular_function	RNA binding
R	0003729	molecular_function	mRNA binding
R	0003735	molecular_function	structural constituent of ribosome
R	0005515	molecular_function	protein binding
R	0005654	cellular_component	nucleoplasm
R	0005737	cellular_component	cytoplasm
R	0005783	cellular_component	endoplasmic reticulum
R	0005791	cellular_component	rough endoplasmic reticulum
R	0005829	cellular_component	cytosol
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
R	0015935	cellular_component	small ribosomal subunit
R	0016020	cellular_component	membrane
R	0022626	cellular_component	cytosolic ribosome
R	0022627	cellular_component	cytosolic small ribosomal subunit
R	0033119	biological_process	negative regulation of RNA splicing
R	0045202	cellular_component	synapse
R	0045296	molecular_function	cadherin binding
R	0070062	cellular_component	extracellular exosome
R	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
R	1990904	cellular_component	ribonucleoprotein complex
S	0000028	biological_process	ribosomal small subunit assembly
S	0002181	biological_process	cytoplasmic translation
S	0003723	molecular_function	RNA binding
S	0003729	molecular_function	mRNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005515	molecular_function	protein binding
S	0005634	cellular_component	nucleus
S	0005654	cellular_component	nucleoplasm
S	0005730	cellular_component	nucleolus
S	0005737	cellular_component	cytoplasm
S	0005783	cellular_component	endoplasmic reticulum
S	0005829	cellular_component	cytosol
S	0005840	cellular_component	ribosome
S	0006364	biological_process	rRNA processing
S	0006412	biological_process	translation
S	0008284	biological_process	positive regulation of cell population proliferation
S	0015935	cellular_component	small ribosomal subunit
S	0016020	cellular_component	membrane
S	0019901	molecular_function	protein kinase binding
S	0022626	cellular_component	cytosolic ribosome
S	0022627	cellular_component	cytosolic small ribosomal subunit
S	0030425	cellular_component	dendrite
S	0031929	biological_process	TOR signaling
S	0032040	cellular_component	small-subunit processome
S	0032868	biological_process	response to insulin
S	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
S	0042274	biological_process	ribosomal small subunit biogenesis
S	0042593	biological_process	glucose homeostasis
S	0043065	biological_process	positive regulation of apoptotic process
S	0044297	cellular_component	cell body
S	0071361	biological_process	cellular response to ethanol
S	0098793	cellular_component	presynapse
S	0098982	cellular_component	GABA-ergic synapse
S	1903347	biological_process	negative regulation of bicellular tight junction assembly
S	1990904	cellular_component	ribonucleoprotein complex
T	0000028	biological_process	ribosomal small subunit assembly
T	0000122	biological_process	negative regulation of transcription by RNA polymerase II
T	0002181	biological_process	cytoplasmic translation
T	0003723	molecular_function	RNA binding
T	0003735	molecular_function	structural constituent of ribosome
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005654	cellular_component	nucleoplasm
T	0005730	cellular_component	nucleolus
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0005840	cellular_component	ribosome
T	0005925	cellular_component	focal adhesion
T	0006412	biological_process	translation
T	0014069	cellular_component	postsynaptic density
T	0016020	cellular_component	membrane
T	0022626	cellular_component	cytosolic ribosome
T	0022627	cellular_component	cytosolic small ribosomal subunit
T	0030218	biological_process	erythrocyte differentiation
T	0030490	biological_process	maturation of SSU-rRNA
T	0032040	cellular_component	small-subunit processome
T	0042274	biological_process	ribosomal small subunit biogenesis
T	0045202	cellular_component	synapse
T	0048027	molecular_function	mRNA 5'-UTR binding
T	0070062	cellular_component	extracellular exosome
T	1990904	cellular_component	ribonucleoprotein complex
U	0001701	biological_process	in utero embryonic development
U	0001731	biological_process	formation of translation preinitiation complex
U	0002176	biological_process	male germ cell proliferation
U	0002183	biological_process	cytoplasmic translational initiation
U	0003723	molecular_function	RNA binding
U	0003729	molecular_function	mRNA binding
U	0003743	molecular_function	translation initiation factor activity
U	0005515	molecular_function	protein binding
U	0005634	cellular_component	nucleus
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0005850	cellular_component	eukaryotic translation initiation factor 2 complex
U	0006412	biological_process	translation
U	0006413	biological_process	translational initiation
U	0008135	molecular_function	translation factor activity, RNA binding
U	0008270	molecular_function	zinc ion binding
U	0008584	biological_process	male gonad development
U	0031369	molecular_function	translation initiation factor binding
U	0045202	cellular_component	synapse
U	0046872	molecular_function	metal ion binding
V	0002181	biological_process	cytoplasmic translation
V	0003723	molecular_function	RNA binding
V	0003729	molecular_function	mRNA binding
V	0003735	molecular_function	structural constituent of ribosome
V	0005515	molecular_function	protein binding
V	0005634	cellular_component	nucleus
V	0005654	cellular_component	nucleoplasm
V	0005730	cellular_component	nucleolus
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0005840	cellular_component	ribosome
V	0005925	cellular_component	focal adhesion
V	0006412	biological_process	translation
V	0014069	cellular_component	postsynaptic density
V	0016020	cellular_component	membrane
V	0022626	cellular_component	cytosolic ribosome
V	0022627	cellular_component	cytosolic small ribosomal subunit
V	0032040	cellular_component	small-subunit processome
V	0033119	biological_process	negative regulation of RNA splicing
V	0042274	biological_process	ribosomal small subunit biogenesis
V	0048027	molecular_function	mRNA 5'-UTR binding
V	0070062	cellular_component	extracellular exosome
V	0070181	molecular_function	small ribosomal subunit rRNA binding
V	1990904	cellular_component	ribonucleoprotein complex
X	0002181	biological_process	cytoplasmic translation
X	0003723	molecular_function	RNA binding
X	0003735	molecular_function	structural constituent of ribosome
X	0005515	molecular_function	protein binding
X	0005634	cellular_component	nucleus
X	0005654	cellular_component	nucleoplasm
X	0005730	cellular_component	nucleolus
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0005840	cellular_component	ribosome
X	0005925	cellular_component	focal adhesion
X	0006412	biological_process	translation
X	0016020	cellular_component	membrane
X	0019843	molecular_function	rRNA binding
X	0022626	cellular_component	cytosolic ribosome
X	0022627	cellular_component	cytosolic small ribosomal subunit
X	0032040	cellular_component	small-subunit processome
X	0042274	biological_process	ribosomal small subunit biogenesis
X	0045202	cellular_component	synapse
X	0070062	cellular_component	extracellular exosome
X	1990904	cellular_component	ribonucleoprotein complex
Y	0002181	biological_process	cytoplasmic translation
Y	0003723	molecular_function	RNA binding
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005515	molecular_function	protein binding
Y	0005634	cellular_component	nucleus
Y	0005654	cellular_component	nucleoplasm
Y	0005730	cellular_component	nucleolus
Y	0005737	cellular_component	cytoplasm
Y	0005829	cellular_component	cytosol
Y	0005840	cellular_component	ribosome
Y	0005925	cellular_component	focal adhesion
Y	0006412	biological_process	translation
Y	0008284	biological_process	positive regulation of cell population proliferation
Y	0015935	cellular_component	small ribosomal subunit
Y	0016020	cellular_component	membrane
Y	0019843	molecular_function	rRNA binding
Y	0022626	cellular_component	cytosolic ribosome
Y	0022627	cellular_component	cytosolic small ribosomal subunit
Y	0032040	cellular_component	small-subunit processome
Y	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
Y	0042274	biological_process	ribosomal small subunit biogenesis
Y	0045727	biological_process	positive regulation of translation
Y	0070062	cellular_component	extracellular exosome
Y	1990904	cellular_component	ribonucleoprotein complex
Z	0002181	biological_process	cytoplasmic translation
Z	0003723	molecular_function	RNA binding
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005515	molecular_function	protein binding
Z	0005634	cellular_component	nucleus
Z	0005654	cellular_component	nucleoplasm
Z	0005730	cellular_component	nucleolus
Z	0005737	cellular_component	cytoplasm
Z	0005829	cellular_component	cytosol
Z	0005840	cellular_component	ribosome
Z	0005925	cellular_component	focal adhesion
Z	0006412	biological_process	translation
Z	0015935	cellular_component	small ribosomal subunit
Z	0016020	cellular_component	membrane
Z	0019843	molecular_function	rRNA binding
Z	0022626	cellular_component	cytosolic ribosome
Z	0022627	cellular_component	cytosolic small ribosomal subunit
Z	0032040	cellular_component	small-subunit processome
Z	0042274	biological_process	ribosomal small subunit biogenesis
Z	0045202	cellular_component	synapse
Z	0070062	cellular_component	extracellular exosome
Z	1990904	cellular_component	ribonucleoprotein complex
a	0002181	biological_process	cytoplasmic translation
a	0003723	molecular_function	RNA binding
a	0003735	molecular_function	structural constituent of ribosome
a	0005515	molecular_function	protein binding
a	0005634	cellular_component	nucleus
a	0005654	cellular_component	nucleoplasm
a	0005730	cellular_component	nucleolus
a	0005737	cellular_component	cytoplasm
a	0005783	cellular_component	endoplasmic reticulum
a	0005791	cellular_component	rough endoplasmic reticulum
a	0005829	cellular_component	cytosol
a	0005840	cellular_component	ribosome
a	0006412	biological_process	translation
a	0015935	cellular_component	small ribosomal subunit
a	0016020	cellular_component	membrane
a	0022626	cellular_component	cytosolic ribosome
a	0022627	cellular_component	cytosolic small ribosomal subunit
a	0032040	cellular_component	small-subunit processome
a	0034063	biological_process	stress granule assembly
a	0042274	biological_process	ribosomal small subunit biogenesis
a	0045202	cellular_component	synapse
a	1990145	biological_process	maintenance of translational fidelity
a	1990904	cellular_component	ribonucleoprotein complex
b	0003735	molecular_function	structural constituent of ribosome
b	0005840	cellular_component	ribosome
b	0006412	biological_process	translation
c	0002181	biological_process	cytoplasmic translation
c	0003723	molecular_function	RNA binding
c	0003735	molecular_function	structural constituent of ribosome
c	0005515	molecular_function	protein binding
c	0005634	cellular_component	nucleus
c	0005654	cellular_component	nucleoplasm
c	0005730	cellular_component	nucleolus
c	0005737	cellular_component	cytoplasm
c	0005829	cellular_component	cytosol
c	0005840	cellular_component	ribosome
c	0006412	biological_process	translation
c	0008284	biological_process	positive regulation of cell population proliferation
c	0009615	biological_process	response to virus
c	0016020	cellular_component	membrane
c	0022626	cellular_component	cytosolic ribosome
c	0022627	cellular_component	cytosolic small ribosomal subunit
c	0032040	cellular_component	small-subunit processome
c	0042274	biological_process	ribosomal small subunit biogenesis
c	0045787	biological_process	positive regulation of cell cycle
c	0070062	cellular_component	extracellular exosome
c	1990904	cellular_component	ribonucleoprotein complex
d	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
d	0002181	biological_process	cytoplasmic translation
d	0003723	molecular_function	RNA binding
d	0003735	molecular_function	structural constituent of ribosome
d	0005515	molecular_function	protein binding
d	0005634	cellular_component	nucleus
d	0005654	cellular_component	nucleoplasm
d	0005730	cellular_component	nucleolus
d	0005737	cellular_component	cytoplasm
d	0005783	cellular_component	endoplasmic reticulum
d	0005829	cellular_component	cytosol
d	0005840	cellular_component	ribosome
d	0005925	cellular_component	focal adhesion
d	0006412	biological_process	translation
d	0016020	cellular_component	membrane
d	0022626	cellular_component	cytosolic ribosome
d	0022627	cellular_component	cytosolic small ribosomal subunit
d	0032040	cellular_component	small-subunit processome
d	0042274	biological_process	ribosomal small subunit biogenesis
d	0070062	cellular_component	extracellular exosome
d	1990904	cellular_component	ribonucleoprotein complex
e	0002181	biological_process	cytoplasmic translation
e	0003723	molecular_function	RNA binding
e	0003735	molecular_function	structural constituent of ribosome
e	0005634	cellular_component	nucleus
e	0005654	cellular_component	nucleoplasm
e	0005730	cellular_component	nucleolus
e	0005737	cellular_component	cytoplasm
e	0005783	cellular_component	endoplasmic reticulum
e	0005829	cellular_component	cytosol
e	0005840	cellular_component	ribosome
e	0006364	biological_process	rRNA processing
e	0006412	biological_process	translation
e	0015935	cellular_component	small ribosomal subunit
e	0016020	cellular_component	membrane
e	0022626	cellular_component	cytosolic ribosome
e	0022627	cellular_component	cytosolic small ribosomal subunit
e	0031369	molecular_function	translation initiation factor binding
e	0032040	cellular_component	small-subunit processome
e	0034101	biological_process	erythrocyte homeostasis
e	0042274	biological_process	ribosomal small subunit biogenesis
e	1990904	cellular_component	ribonucleoprotein complex
f	0002181	biological_process	cytoplasmic translation
f	0003723	molecular_function	RNA binding
f	0003729	molecular_function	mRNA binding
f	0003735	molecular_function	structural constituent of ribosome
f	0005515	molecular_function	protein binding
f	0005634	cellular_component	nucleus
f	0005654	cellular_component	nucleoplasm
f	0005730	cellular_component	nucleolus
f	0005737	cellular_component	cytoplasm
f	0005829	cellular_component	cytosol
f	0005840	cellular_component	ribosome
f	0005925	cellular_component	focal adhesion
f	0006412	biological_process	translation
f	0006413	biological_process	translational initiation
f	0006450	biological_process	regulation of translational fidelity
f	0015935	cellular_component	small ribosomal subunit
f	0016020	cellular_component	membrane
f	0019843	molecular_function	rRNA binding
f	0022626	cellular_component	cytosolic ribosome
f	0022627	cellular_component	cytosolic small ribosomal subunit
f	0032040	cellular_component	small-subunit processome
f	0042274	biological_process	ribosomal small subunit biogenesis
f	0045202	cellular_component	synapse
f	0070062	cellular_component	extracellular exosome
f	1990904	cellular_component	ribonucleoprotein complex
g	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
g	0002181	biological_process	cytoplasmic translation
g	0003723	molecular_function	RNA binding
g	0003735	molecular_function	structural constituent of ribosome
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0005654	cellular_component	nucleoplasm
g	0005730	cellular_component	nucleolus
g	0005737	cellular_component	cytoplasm
g	0005829	cellular_component	cytosol
g	0005840	cellular_component	ribosome
g	0005925	cellular_component	focal adhesion
g	0006364	biological_process	rRNA processing
g	0006412	biological_process	translation
g	0015935	cellular_component	small ribosomal subunit
g	0016020	cellular_component	membrane
g	0022626	cellular_component	cytosolic ribosome
g	0022627	cellular_component	cytosolic small ribosomal subunit
g	0032040	cellular_component	small-subunit processome
g	0042274	biological_process	ribosomal small subunit biogenesis
g	0045202	cellular_component	synapse
g	0070062	cellular_component	extracellular exosome
g	1990830	biological_process	cellular response to leukemia inhibitory factor
g	1990904	cellular_component	ribonucleoprotein complex
h	0000977	molecular_function	RNA polymerase II transcription regulatory region sequence-specific DNA binding
h	0002181	biological_process	cytoplasmic translation
h	0003677	molecular_function	DNA binding
h	0003684	molecular_function	damaged DNA binding
h	0003723	molecular_function	RNA binding
h	0003729	molecular_function	mRNA binding
h	0003735	molecular_function	structural constituent of ribosome
h	0003906	molecular_function	DNA-(apurinic or apyrimidinic site) endonuclease activity
h	0004520	molecular_function	DNA endonuclease activity
h	0005515	molecular_function	protein binding
h	0005634	cellular_component	nucleus
h	0005654	cellular_component	nucleoplasm
h	0005730	cellular_component	nucleolus
h	0005737	cellular_component	cytoplasm
h	0005739	cellular_component	mitochondrion
h	0005743	cellular_component	mitochondrial inner membrane
h	0005759	cellular_component	mitochondrial matrix
h	0005783	cellular_component	endoplasmic reticulum
h	0005819	cellular_component	spindle
h	0005829	cellular_component	cytosol
h	0005840	cellular_component	ribosome
h	0005856	cellular_component	cytoskeleton
h	0005886	cellular_component	plasma membrane
h	0005925	cellular_component	focal adhesion
h	0006281	biological_process	DNA repair
h	0006284	biological_process	base-excision repair
h	0006412	biological_process	translation
h	0006413	biological_process	translational initiation
h	0006417	biological_process	regulation of translation
h	0006915	biological_process	apoptotic process
h	0006974	biological_process	DNA damage response
h	0007059	biological_process	chromosome segregation
h	0008017	molecular_function	microtubule binding
h	0010628	biological_process	positive regulation of gene expression
h	0014069	cellular_component	postsynaptic density
h	0015631	molecular_function	tubulin binding
h	0015935	cellular_component	small ribosomal subunit
h	0016020	cellular_component	membrane
h	0016829	molecular_function	lyase activity
h	0017148	biological_process	negative regulation of translation
h	0019104	molecular_function	DNA N-glycosylase activity
h	0019899	molecular_function	enzyme binding
h	0019900	molecular_function	kinase binding
h	0019901	molecular_function	protein kinase binding
h	0022626	cellular_component	cytosolic ribosome
h	0022627	cellular_component	cytosolic small ribosomal subunit
h	0030544	molecular_function	Hsp70 protein binding
h	0031116	biological_process	positive regulation of microtubule polymerization
h	0031334	biological_process	positive regulation of protein-containing complex assembly
h	0031397	biological_process	negative regulation of protein ubiquitination
h	0032079	biological_process	positive regulation of endodeoxyribonuclease activity
h	0032357	molecular_function	oxidized purine DNA binding
h	0032358	molecular_function	oxidized pyrimidine DNA binding
h	0032587	cellular_component	ruffle membrane
h	0032743	biological_process	positive regulation of interleukin-2 production
h	0034614	biological_process	cellular response to reactive oxygen species
h	0042104	biological_process	positive regulation of activated T cell proliferation
h	0042981	biological_process	regulation of apoptotic process
h	0044390	molecular_function	ubiquitin-like protein conjugating enzyme binding
h	0044877	molecular_function	protein-containing complex binding
h	0045202	cellular_component	synapse
h	0045738	biological_process	negative regulation of DNA repair
h	0045739	biological_process	positive regulation of DNA repair
h	0050862	biological_process	positive regulation of T cell receptor signaling pathway
h	0051018	molecular_function	protein kinase A binding
h	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
h	0051225	biological_process	spindle assembly
h	0051301	biological_process	cell division
h	0051536	molecular_function	iron-sulfur cluster binding
h	0051879	molecular_function	Hsp90 protein binding
h	0061481	biological_process	response to TNF agonist
h	0070062	cellular_component	extracellular exosome
h	0070181	molecular_function	small ribosomal subunit rRNA binding
h	0070301	biological_process	cellular response to hydrogen peroxide
h	0071159	cellular_component	NF-kappaB complex
h	0071356	biological_process	cellular response to tumor necrosis factor
h	0072686	cellular_component	mitotic spindle
h	0097100	molecular_function	supercoiled DNA binding
h	0140078	molecular_function	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
h	0140297	molecular_function	DNA-binding transcription factor binding
h	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
h	1902231	biological_process	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
h	1905053	biological_process	positive regulation of base-excision repair
h	1990904	cellular_component	ribonucleoprotein complex
h	2001235	biological_process	positive regulation of apoptotic signaling pathway
i	0002181	biological_process	cytoplasmic translation
i	0003723	molecular_function	RNA binding
i	0003735	molecular_function	structural constituent of ribosome
i	0005515	molecular_function	protein binding
i	0005634	cellular_component	nucleus
i	0005654	cellular_component	nucleoplasm
i	0005730	cellular_component	nucleolus
i	0005737	cellular_component	cytoplasm
i	0005829	cellular_component	cytosol
i	0005840	cellular_component	ribosome
i	0005925	cellular_component	focal adhesion
i	0006412	biological_process	translation
i	0016020	cellular_component	membrane
i	0022626	cellular_component	cytosolic ribosome
i	0022627	cellular_component	cytosolic small ribosomal subunit
i	0045202	cellular_component	synapse
i	1990904	cellular_component	ribonucleoprotein complex
j	0000028	biological_process	ribosomal small subunit assembly
j	0000056	biological_process	ribosomal small subunit export from nucleus
j	0001649	biological_process	osteoblast differentiation
j	0002181	biological_process	cytoplasmic translation
j	0003677	molecular_function	DNA binding
j	0003723	molecular_function	RNA binding
j	0003735	molecular_function	structural constituent of ribosome
j	0005515	molecular_function	protein binding
j	0005634	cellular_component	nucleus
j	0005654	cellular_component	nucleoplasm
j	0005737	cellular_component	cytoplasm
j	0005829	cellular_component	cytosol
j	0005840	cellular_component	ribosome
j	0005925	cellular_component	focal adhesion
j	0006364	biological_process	rRNA processing
j	0006412	biological_process	translation
j	0015935	cellular_component	small ribosomal subunit
j	0016020	cellular_component	membrane
j	0022626	cellular_component	cytosolic ribosome
j	0022627	cellular_component	cytosolic small ribosomal subunit
j	0042274	biological_process	ribosomal small subunit biogenesis
j	0045202	cellular_component	synapse
j	0097371	molecular_function	MDM2/MDM4 family protein binding
j	0097421	biological_process	liver regeneration
j	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
j	1990904	cellular_component	ribonucleoprotein complex
j	1990948	molecular_function	ubiquitin ligase inhibitor activity
k	0001891	cellular_component	phagocytic cup
k	0001934	biological_process	positive regulation of protein phosphorylation
k	0002181	biological_process	cytoplasmic translation
k	0003723	molecular_function	RNA binding
k	0005080	molecular_function	protein kinase C binding
k	0005102	molecular_function	signaling receptor binding
k	0005515	molecular_function	protein binding
k	0005634	cellular_component	nucleus
k	0005654	cellular_component	nucleoplasm
k	0005737	cellular_component	cytoplasm
k	0005739	cellular_component	mitochondrion
k	0005829	cellular_component	cytosol
k	0005840	cellular_component	ribosome
k	0005886	cellular_component	plasma membrane
k	0006412	biological_process	translation
k	0006417	biological_process	regulation of translation
k	0006915	biological_process	apoptotic process
k	0007369	biological_process	gastrulation
k	0008047	molecular_function	enzyme activator activity
k	0008200	molecular_function	ion channel inhibitor activity
k	0008656	molecular_function	cysteine-type endopeptidase activator activity involved in apoptotic process
k	0010629	biological_process	negative regulation of gene expression
k	0015935	cellular_component	small ribosomal subunit
k	0016020	cellular_component	membrane
k	0016567	biological_process	protein ubiquitination
k	0017148	biological_process	negative regulation of translation
k	0019899	molecular_function	enzyme binding
k	0019903	molecular_function	protein phosphatase binding
k	0022627	cellular_component	cytosolic small ribosomal subunit
k	0030178	biological_process	negative regulation of Wnt signaling pathway
k	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
k	0030292	molecular_function	protein tyrosine kinase inhibitor activity
k	0030308	biological_process	negative regulation of cell growth
k	0030332	molecular_function	cyclin binding
k	0030335	biological_process	positive regulation of cell migration
k	0030425	cellular_component	dendrite
k	0030496	cellular_component	midbody
k	0030971	molecular_function	receptor tyrosine kinase binding
k	0031334	biological_process	positive regulation of protein-containing complex assembly
k	0032091	biological_process	negative regulation of protein binding
k	0032436	biological_process	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
k	0032880	biological_process	regulation of protein localization
k	0035591	molecular_function	signaling adaptor activity
k	0042169	molecular_function	SH2 domain binding
k	0042802	molecular_function	identical protein binding
k	0042803	molecular_function	protein homodimerization activity
k	0042995	cellular_component	cell projection
k	0042998	biological_process	positive regulation of Golgi to plasma membrane protein transport
k	0043005	cellular_component	neuron projection
k	0043022	molecular_function	ribosome binding
k	0043025	cellular_component	neuronal cell body
k	0043065	biological_process	positive regulation of apoptotic process
k	0043204	cellular_component	perikaryon
k	0043473	biological_process	pigmentation
k	0043547	biological_process	positive regulation of GTPase activity
k	0044297	cellular_component	cell body
k	0045182	molecular_function	translation regulator activity
k	0045296	molecular_function	cadherin binding
k	0045879	biological_process	negative regulation of smoothened signaling pathway
k	0048471	cellular_component	perinuclear region of cytoplasm
k	0048511	biological_process	rhythmic process
k	0050765	biological_process	negative regulation of phagocytosis
k	0051302	biological_process	regulation of cell division
k	0051434	molecular_function	BH3 domain binding
k	0051726	biological_process	regulation of cell cycle
k	0051898	biological_process	negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
k	0051901	biological_process	positive regulation of mitochondrial depolarization
k	0060090	molecular_function	molecular adaptor activity
k	0070062	cellular_component	extracellular exosome
k	0071333	biological_process	cellular response to glucose stimulus
k	0071363	biological_process	cellular response to growth factor stimulus
k	0072344	biological_process	rescue of stalled ribosome
k	0106070	biological_process	regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
k	1900102	biological_process	negative regulation of endoplasmic reticulum unfolded protein response
k	1903751	biological_process	negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
k	1990630	cellular_component	IRE1-RACK1-PP2A complex
k	1990904	cellular_component	ribonucleoprotein complex
k	2000114	biological_process	regulation of establishment of cell polarity
k	2000543	biological_process	positive regulation of gastrulation
k	2001125	biological_process	negative regulation of translational frameshifting
k	2001244	biological_process	positive regulation of intrinsic apoptotic signaling pathway
l	0000028	biological_process	ribosomal small subunit assembly
l	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
l	0002181	biological_process	cytoplasmic translation
l	0002548	biological_process	monocyte chemotaxis
l	0003723	molecular_function	RNA binding
l	0003735	molecular_function	structural constituent of ribosome
l	0005515	molecular_function	protein binding
l	0005634	cellular_component	nucleus
l	0005654	cellular_component	nucleoplasm
l	0005730	cellular_component	nucleolus
l	0005737	cellular_component	cytoplasm
l	0005829	cellular_component	cytosol
l	0005840	cellular_component	ribosome
l	0005925	cellular_component	focal adhesion
l	0006364	biological_process	rRNA processing
l	0006412	biological_process	translation
l	0007000	biological_process	nucleolus organization
l	0014069	cellular_component	postsynaptic density
l	0016020	cellular_component	membrane
l	0017134	molecular_function	fibroblast growth factor binding
l	0019901	molecular_function	protein kinase binding
l	0022626	cellular_component	cytosolic ribosome
l	0022627	cellular_component	cytosolic small ribosomal subunit
l	0030218	biological_process	erythrocyte differentiation
l	0030490	biological_process	maturation of SSU-rRNA
l	0031640	biological_process	killing of cells of another organism
l	0032040	cellular_component	small-subunit processome
l	0042274	biological_process	ribosomal small subunit biogenesis
l	0042802	molecular_function	identical protein binding
l	0050829	biological_process	defense response to Gram-negative bacterium
l	0060265	biological_process	positive regulation of respiratory burst involved in inflammatory response
l	0060266	biological_process	negative regulation of respiratory burst involved in inflammatory response
l	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
l	0070062	cellular_component	extracellular exosome
l	1990904	cellular_component	ribonucleoprotein complex
m	0002181	biological_process	cytoplasmic translation
m	0003723	molecular_function	RNA binding
m	0003735	molecular_function	structural constituent of ribosome
m	0005515	molecular_function	protein binding
m	0005634	cellular_component	nucleus
m	0005654	cellular_component	nucleoplasm
m	0005730	cellular_component	nucleolus
m	0005737	cellular_component	cytoplasm
m	0005829	cellular_component	cytosol
m	0005840	cellular_component	ribosome
m	0006364	biological_process	rRNA processing
m	0006412	biological_process	translation
m	0014069	cellular_component	postsynaptic density
m	0015935	cellular_component	small ribosomal subunit
m	0022626	cellular_component	cytosolic ribosome
m	0022627	cellular_component	cytosolic small ribosomal subunit
m	0042274	biological_process	ribosomal small subunit biogenesis
m	0045202	cellular_component	synapse
m	0070062	cellular_component	extracellular exosome
m	1990904	cellular_component	ribonucleoprotein complex
n	0002181	biological_process	cytoplasmic translation
n	0003676	molecular_function	nucleic acid binding
n	0003723	molecular_function	RNA binding
n	0003735	molecular_function	structural constituent of ribosome
n	0005515	molecular_function	protein binding
n	0005634	cellular_component	nucleus
n	0005654	cellular_component	nucleoplasm
n	0005737	cellular_component	cytoplasm
n	0005829	cellular_component	cytosol
n	0005840	cellular_component	ribosome
n	0005925	cellular_component	focal adhesion
n	0006412	biological_process	translation
n	0014069	cellular_component	postsynaptic density
n	0015935	cellular_component	small ribosomal subunit
n	0016020	cellular_component	membrane
n	0019843	molecular_function	rRNA binding
n	0022626	cellular_component	cytosolic ribosome
n	0022627	cellular_component	cytosolic small ribosomal subunit
n	0045202	cellular_component	synapse
n	0070062	cellular_component	extracellular exosome
n	1990904	cellular_component	ribonucleoprotein complex
o	0002181	biological_process	cytoplasmic translation
o	0003735	molecular_function	structural constituent of ribosome
o	0005654	cellular_component	nucleoplasm
o	0005737	cellular_component	cytoplasm
o	0005783	cellular_component	endoplasmic reticulum
o	0005791	cellular_component	rough endoplasmic reticulum
o	0005829	cellular_component	cytosol
o	0005840	cellular_component	ribosome
o	0005925	cellular_component	focal adhesion
o	0006412	biological_process	translation
o	0008270	molecular_function	zinc ion binding
o	0015935	cellular_component	small ribosomal subunit
o	0022626	cellular_component	cytosolic ribosome
o	0022627	cellular_component	cytosolic small ribosomal subunit
o	0046872	molecular_function	metal ion binding
o	0070062	cellular_component	extracellular exosome
o	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
o	1990904	cellular_component	ribonucleoprotein complex
p	0002181	biological_process	cytoplasmic translation
p	0003723	molecular_function	RNA binding
p	0003735	molecular_function	structural constituent of ribosome
p	0005515	molecular_function	protein binding
p	0005615	cellular_component	extracellular space
p	0005634	cellular_component	nucleus
p	0005654	cellular_component	nucleoplasm
p	0005730	cellular_component	nucleolus
p	0005737	cellular_component	cytoplasm
p	0005741	cellular_component	mitochondrial outer membrane
p	0005783	cellular_component	endoplasmic reticulum
p	0005789	cellular_component	endoplasmic reticulum membrane
p	0005829	cellular_component	cytosol
p	0005840	cellular_component	ribosome
p	0005886	cellular_component	plasma membrane
p	0006412	biological_process	translation
p	0008270	molecular_function	zinc ion binding
p	0010008	cellular_component	endosome membrane
p	0016020	cellular_component	membrane
p	0016567	biological_process	protein ubiquitination
p	0019941	biological_process	modification-dependent protein catabolic process
p	0022626	cellular_component	cytosolic ribosome
p	0022627	cellular_component	cytosolic small ribosomal subunit
p	0030666	cellular_component	endocytic vesicle membrane
p	0031386	molecular_function	protein tag activity
p	0031625	molecular_function	ubiquitin protein ligase binding
p	0031982	cellular_component	vesicle
p	0032040	cellular_component	small-subunit processome
p	0045202	cellular_component	synapse
p	0046872	molecular_function	metal ion binding
p	0070062	cellular_component	extracellular exosome
p	1990904	cellular_component	ribonucleoprotein complex
q	0002181	biological_process	cytoplasmic translation
q	0003723	molecular_function	RNA binding
q	0003735	molecular_function	structural constituent of ribosome
q	0005515	molecular_function	protein binding
q	0005634	cellular_component	nucleus
q	0005654	cellular_component	nucleoplasm
q	0005730	cellular_component	nucleolus
q	0005737	cellular_component	cytoplasm
q	0005794	cellular_component	Golgi apparatus
q	0005829	cellular_component	cytosol
q	0005840	cellular_component	ribosome
q	0006412	biological_process	translation
q	0016020	cellular_component	membrane
q	0022626	cellular_component	cytosolic ribosome
q	0022627	cellular_component	cytosolic small ribosomal subunit
q	0032040	cellular_component	small-subunit processome
q	0042274	biological_process	ribosomal small subunit biogenesis
q	0090263	biological_process	positive regulation of canonical Wnt signaling pathway
q	1990145	biological_process	maintenance of translational fidelity
q	1990904	cellular_component	ribonucleoprotein complex
s	0000028	biological_process	ribosomal small subunit assembly
s	0002181	biological_process	cytoplasmic translation
s	0003723	molecular_function	RNA binding
s	0003735	molecular_function	structural constituent of ribosome
s	0005515	molecular_function	protein binding
s	0005634	cellular_component	nucleus
s	0005654	cellular_component	nucleoplasm
s	0005730	cellular_component	nucleolus
s	0005737	cellular_component	cytoplasm
s	0005783	cellular_component	endoplasmic reticulum
s	0005791	cellular_component	rough endoplasmic reticulum
s	0005829	cellular_component	cytosol
s	0005840	cellular_component	ribosome
s	0006364	biological_process	rRNA processing
s	0006412	biological_process	translation
s	0015935	cellular_component	small ribosomal subunit
s	0022626	cellular_component	cytosolic ribosome
s	0022627	cellular_component	cytosolic small ribosomal subunit
s	0030490	biological_process	maturation of SSU-rRNA
s	0032040	cellular_component	small-subunit processome
s	0042254	biological_process	ribosome biogenesis
s	0042274	biological_process	ribosomal small subunit biogenesis
s	0045202	cellular_component	synapse
s	0070062	cellular_component	extracellular exosome
s	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
s	1990904	cellular_component	ribonucleoprotein complex
v	0002181	biological_process	cytoplasmic translation
v	0003723	molecular_function	RNA binding
v	0003735	molecular_function	structural constituent of ribosome
v	0005634	cellular_component	nucleus
v	0005654	cellular_component	nucleoplasm
v	0005730	cellular_component	nucleolus
v	0005737	cellular_component	cytoplasm
v	0005829	cellular_component	cytosol
v	0005840	cellular_component	ribosome
v	0005925	cellular_component	focal adhesion
v	0006364	biological_process	rRNA processing
v	0006412	biological_process	translation
v	0006413	biological_process	translational initiation
v	0016020	cellular_component	membrane
v	0022626	cellular_component	cytosolic ribosome
v	0022627	cellular_component	cytosolic small ribosomal subunit
v	0032040	cellular_component	small-subunit processome
v	0034101	biological_process	erythrocyte homeostasis
v	0042274	biological_process	ribosomal small subunit biogenesis
v	1990904	cellular_component	ribonucleoprotein complex
w	0002181	biological_process	cytoplasmic translation
w	0003723	molecular_function	RNA binding
w	0003735	molecular_function	structural constituent of ribosome
w	0005515	molecular_function	protein binding
w	0005654	cellular_component	nucleoplasm
w	0005737	cellular_component	cytoplasm
w	0005829	cellular_component	cytosol
w	0005840	cellular_component	ribosome
w	0006412	biological_process	translation
w	0015935	cellular_component	small ribosomal subunit
w	0016020	cellular_component	membrane
w	0022626	cellular_component	cytosolic ribosome
w	0022627	cellular_component	cytosolic small ribosomal subunit
w	0045202	cellular_component	synapse
w	0070062	cellular_component	extracellular exosome
w	0097371	molecular_function	MDM2/MDM4 family protein binding
w	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
w	1990904	cellular_component	ribonucleoprotein complex
w	1990948	molecular_function	ubiquitin ligase inhibitor activity
x	0001732	biological_process	formation of cytoplasmic translation initiation complex
x	0002183	biological_process	cytoplasmic translational initiation
x	0002191	biological_process	cap-dependent translational initiation
x	0003723	molecular_function	RNA binding
x	0003743	molecular_function	translation initiation factor activity
x	0005515	molecular_function	protein binding
x	0005737	cellular_component	cytoplasm
x	0005829	cellular_component	cytosol
x	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
x	0006412	biological_process	translation
x	0006413	biological_process	translational initiation
x	0016020	cellular_component	membrane
x	0016282	cellular_component	eukaryotic 43S preinitiation complex
x	0033290	cellular_component	eukaryotic 48S preinitiation complex
x	0045202	cellular_component	synapse
x	0071541	cellular_component	eukaryotic translation initiation factor 3 complex, eIF3m
x	0075522	biological_process	IRES-dependent viral translational initiation
x	0075525	biological_process	viral translational termination-reinitiation
x	0098808	molecular_function	mRNA cap binding

Functional Information from PROSITE/UniProt

site_id	PS00039
Number of Residues	9
Details	DEAD_ATP_HELICASE DEAD-box subfamily ATP-dependent helicases signature. VLDEADEmL

Chain	Residue	Details
3	VAL180-LEU188

---

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. ErLtnsMMmhgrnnGKKlmtvrIVkhA

Chain	Residue	Details
f	GLU70-ALA96

---

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GfiVLTTSaGIMdheeAR

Chain	Residue	Details
c	GLY100-ARG117

---

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. LrALarS.GMkIgrieDvTPiPSD

Chain	Residue	Details
T	LEU116-ASP138

---

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KqPNSAiR

Chain	Residue	Details
a	LYS60-ARG67

---

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDiVtVgEcRPLS

Chain	Residue	Details
X	GLY123-SER135

---

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD

Chain	Residue	Details
p	LYS27-ASP52

---

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. NGKtfnqveIkpemIGhyLGEFsiT

Chain	Residue	Details
j	ASN98-THR122

---

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGhvAQiyAirqSiSKAL

Chain	Residue	Details
g	GLY74-LEU92

---

site_id	PS00361
Number of Residues	16
Details	RIBOSOMAL_S10 Ribosomal protein S10 signature. AkekNLkvkGPVrMPT

Chain	Residue	Details
w	ALA43-THR58

---

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. VrkHLernRkDkdAkfrLilIesrihrLarY

Chain	Residue	Details
V	VAL98-TYR128

---

site_id	PS00527
Number of Residues	23
Details	RIBOSOMAL_S14 Ribosomal protein S14 signature. RvCsnrhglirkyg.LNMCRqCFR

Chain	Residue	Details
o	ARG22-ARG44

---

site_id	PS00528
Number of Residues	15
Details	RIBOSOMAL_S4E Ribosomal protein S4e signature. HlKRVAaPkhWmLdK

Chain	Residue	Details
Y	HIS8-LYS22

---

site_id	PS00529
Number of Residues	23
Details	RIBOSOMAL_S24E Ribosomal protein S24e signature. FGggKTtGFGmIYDSldyakknE

Chain	Residue	Details
e	PHE64-GLU86

---

site_id	PS00548
Number of Residues	37
Details	RIBOSOMAL_S3 Ribosomal protein S3 signature. AKsmkfvdGlMihSgdpVnyyVDtavrhvlLrqGvlG

Chain	Residue	Details
h	ALA147-GLY183

---

site_id	PS00578
Number of Residues	12
Details	RIBOSOMAL_S6E Ribosomal protein S6e signature. ISGGnDkqGfPM

Chain	Residue	Details
S	ILE52-MET63

---

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GQrtrFkAfvAIGDyn.GhVGlGvkcsk.EVat.AI

Chain	Residue	Details
O	GLY119-ILE151

---

site_id	PS00628
Number of Residues	20
Details	RIBOSOMAL_S19E Ribosomal protein S19e signature. PshfsrgSksVaRrVLQaLE

Chain	Residue	Details
l	PRO89-GLU108

---

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLqtqVFKlglAkSihhARvLI

Chain	Residue	Details
Z	LEU106-ILE130

---

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHfwGlrVRGQ

Chain	Residue	Details
n	ARG121-GLN134

---

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. ALSGswDgTLRLWDL

Chain	Residue	Details
k	ALA78-LEU92
k	ILE120-THR134
k	ILE165-LEU179
k	CYS207-LEU221
F	VAL67-CYS81

---

site_id	PS00712
Number of Residues	16
Details	RIBOSOMAL_S17E Ribosomal protein S17e signature. IpSKkLRNkIAGYvTH

Chain	Residue	Details
v	ILE41-HIS56

---

site_id	PS00733
Number of Residues	8
Details	RIBOSOMAL_S26E Ribosomal protein S26e signature. YCVSCAIH

Chain	Residue	Details
R	TYR73-HIS80

---

site_id	PS00948
Number of Residues	14
Details	RIBOSOMAL_S7E Ribosomal protein S7e signature. RLvRELEKKFSgKH

Chain	Residue	Details
L	ARG78-HIS91

---

site_id	PS00961
Number of Residues	9
Details	RIBOSOMAL_S28E Ribosomal protein S28e signature. ESEREARrL

Chain	Residue	Details
s	GLU60-LEU68

---

site_id	PS00962
Number of Residues	12
Details	RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. VlKFLAAGTHLG

Chain	Residue	Details
Q	VAL15-GLY26

---

site_id	PS00963
Number of Residues	25
Details	RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PrlLVVtDpraDhqpLtEasyvNLP

Chain	Residue	Details
Q	PRO119-PRO143

---

site_id	PS00996
Number of Residues	9
Details	RIBOSOMAL_S21E Ribosomal protein S21e signature. LYVPRKCSA

Chain	Residue	Details
N	LEU11-ALA19

---

site_id	PS01168
Number of Residues	33
Details	RIBOSOMAL_S27E Ribosomal protein S27e signature. KCpgCykittvFShAqtvvlCvgCStvLcqPtG

Chain	Residue	Details
M	LYS36-GLY68

---

site_id	PS01189
Number of Residues	19
Details	RIBOSOMAL_S12E Ribosomal protein S12e signature. ALQevLktAlihDGLarGI

Chain	Residue	Details
q	ALA17-ILE35

---

site_id	PS01191
Number of Residues	13
Details	RIBOSOMAL_S3AE Ribosomal protein S3Ae signature. LkGRVfEvSLaDL

Chain	Residue	Details
P	LEU62-LEU74

---

site_id	PS01193
Number of Residues	20
Details	RIBOSOMAL_S8E Ribosomal protein S8e signature. RrkTGGkrkpy.HkKrKyELG

Chain	Residue	Details
d	ARG11-GLY30

---

site_id	PS01262
Number of Residues	23
Details	IF1A Eukaryotic initiation factor 1A signature. MlGnGRleamCfDGvkRlcHIrG

Chain	Residue	Details
G	MET41-GLY63

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1063
Details	Domain: {"description":"PCI","evidences":[{"source":"PROSITE-ProRule","id":"PRU01185","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	124
Details	Region: {"description":"Sufficient for interaction with EPAS1","evidences":[{"source":"PubMed","id":"17324924","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	186
Details	Region: {"description":"Sufficient for interaction with TRIM27","evidences":[{"source":"PubMed","id":"10504338","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"HAMAP-Rule","id":"MF_03004","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17322308","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAR-2008","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Heiserich L.","Gottlieb E.","Matallanas D.","Cooper W.N.","Kolch W."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	264
Details	Domain: {"description":"MPN","evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	33
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"HAMAP-Rule","id":"MF_03005","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17322308","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	21
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	111
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	19
Details	Compositional bias: {"description":"Low complexity","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"HAMAP-Rule","id":"MF_03007","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17322308","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	38
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	38
Details	Coiled coil: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03000","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"HAMAP-Rule","id":"MF_03010","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17322308","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"DEC-2008","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Zebisch A.","Kolch W."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	11
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	30
Details	Region: {"description":"Interaction with HSV-1 and HSV-2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	71
Details	Domain: {"description":"S1 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU00180","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by HRI","evidences":[{"source":"UniProtKB","id":"P83268","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"38340717","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	209
Details	Domain: {"description":"tr-type G","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	7
Details	Region: {"description":"G1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	4
Details	Region: {"description":"G2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	3
Details	Region: {"description":"G3","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	3
Details	Region: {"description":"G4","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	2
Details	Region: {"description":"G5","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	12
Details	Region: {"description":"Interacts with CDC123","evidences":[{"source":"PubMed","id":"35031321","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P32481","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9Z0N1","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	108
Details	Repeat: {"description":"WD 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	108
Details	Repeat: {"description":"WD 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	129
Details	Repeat: {"description":"WD 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	135
Details	Repeat: {"description":"WD 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	130
Details	Repeat: {"description":"WD 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI36
Number of Residues	119
Details	Repeat: {"description":"WD 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI37
Number of Residues	114
Details	Repeat: {"description":"WD 7"}

Chain

Residue

Details

---

site_id	SWS_FT_FI38
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI39
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)"}

Chain

Residue

Details

---

site_id	SWS_FT_FI40
Number of Residues	74
Details	Domain: {"description":"S1-like"}

Chain

Residue

Details

---

site_id	SWS_FT_FI41
Number of Residues	32
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI42
Number of Residues	7
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI43
Number of Residues	1
Details	Site: {"description":"Arginine finger","evidences":[{"source":"PubMed","id":"11166181","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI44
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI45
Number of Residues	83
Details	Domain: {"description":"RRM","evidences":[{"source":"HAMAP-Rule","id":"MF_03001","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI46
Number of Residues	42
Details	Repeat: {"description":"WD 8"}

Chain

Residue

Details

---

site_id	SWS_FT_FI47
Number of Residues	9
Details	Compositional bias: {"description":"Polar residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI48
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q8R1B4","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI49
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"HAMAP-Rule","id":"MF_03002","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17322308","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI50
Number of Residues	6
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI51
Number of Residues	13
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI52
Number of Residues	46
Details	Zinc finger: {"description":"C4-type","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI53
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"34516797","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7MQ8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI54
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17081983","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI55
Number of Residues	1
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAY-2006","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Kanor S.","Tissot J.-D.","Quadroni M."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25944712","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI56
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25114211","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI57
Number of Residues	63
Details	Domain: {"description":"S5 DRBM","evidences":[{"source":"PROSITE-ProRule","id":"PRU00268","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI58
Number of Residues	1
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"28132843","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32011234","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34469731","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI59
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"PubMed","id":"28132843","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI60
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P97351","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI61
Number of Residues	1
Details	Modified residue: {"description":"ADP-ribosyltyrosine","evidences":[{"source":"PubMed","id":"29954836","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI62
Number of Residues	59
Details	Region: {"description":"Interaction with PPP1R16B","evidences":[{"source":"PubMed","id":"16263087","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI63
Number of Residues	19
Details	Region: {"description":"Laminin-binding"}

Chain

Residue

Details

---

site_id	SWS_FT_FI64
Number of Residues	1
Details	Site: {"description":"Cleavage; by ST3; site 1","evidences":[{"source":"HAMAP-Rule","id":"MF_03016","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI65
Number of Residues	1
Details	Site: {"description":"Cleavage; by ST3; site 2","evidences":[{"source":"HAMAP-Rule","id":"MF_03016","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI66
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"HAMAP-Rule","id":"MF_03016","evidenceCode":"ECO:0000255"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUL-2004","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Potts A.","Barblan J.","Quadroni M."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25944712","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI67
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P14206","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI68
Number of Residues	1
Details	Modified residue: {"description":"ADP-ribosyl glutamic acid","evidences":[{"source":"PubMed","id":"34314702","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI69
Number of Residues	1
Details	Modified residue: {"description":"(3R)-3-hydroxyarginine","evidences":[{"source":"PubMed","id":"29563586","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI70
Number of Residues	58
Details	Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI71
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI72
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P41035","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI73
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P62301","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI74
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P62301","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI75
Number of Residues	3
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"36638793","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI76
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P62281","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI77
Number of Residues	1
Details	Modified residue: {"description":"Omega-N-methylarginine","evidences":[{"source":"UniProtKB","id":"P62281","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI78
Number of Residues	1
Details	Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"source":"PubMed","id":"21044946","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI79
Number of Residues	62
Details	Domain: {"description":"S4 RNA-binding"}

Chain

Residue

Details

---

site_id	SWS_FT_FI80
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P62702","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI81
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q6ZWN5","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI82
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P62267","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI83
Number of Residues	1
Details	Modified residue: {"description":"3-hydroxyproline","evidences":[{"source":"PubMed","id":"24550447","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24550462","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28257692","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI84
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P62245","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI85
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P62242","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI86
Number of Residues	1
Details	Lipidation: {"description":"N-myristoyl glycine","evidences":[{"source":"PubMed","id":"25255805","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI87
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI88
Number of Residues	71
Details	Domain: {"description":"KH type-2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00118","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI89
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"FEB-2008","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Murray L.","Brunton V.G.","Frame M.C.","Calvo F.","Kolch W."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25944712","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI90
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by PKC/PRKCD","evidences":[{"source":"PubMed","id":"19059439","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI91
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine; by MAPK","evidences":[{"source":"PubMed","id":"15950189","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI92
Number of Residues	3
Details	Modified residue: {"description":"Asymmetric dimethylarginine; by PRMT1","evidences":[{"source":"PubMed","id":"19460357","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI93
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine; by PKB","evidences":[{"source":"PubMed","id":"20605787","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI94
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P62908","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI95
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by IKKB","evidences":[{"source":"PubMed","id":"21399639","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI96
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine; by CDK1 and PKC/PRKCD","evidences":[{"source":"PubMed","id":"19059439","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21871177","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAR-2009","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Waridel P.","Quadroni M."]}},{"source":"PubMed","id":"16964243","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI97
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"16807684","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI98
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"PubMed","id":"28065601","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28132843","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31981475","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32011234","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34348161","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34469731","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI99
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P63325","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI100
Number of Residues	1
Details	Modified residue: {"description":"N-acetylthreonine; in Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAY-2006","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Kanor S.","Tissot J.-D.","Quadroni M."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI101
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine; by ABL1","evidences":[{"source":"PubMed","id":"19423701","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI102
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P68040","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI103
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"11279199","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI104
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by viral VacV B1 kinase","evidences":[{"source":"PubMed","id":"28636603","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI105
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine; by viral VacV B1 kinase","evidences":[{"source":"PubMed","id":"28636603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI106
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine; by viral VacV B1 kinase","evidences":[{"source":"PubMed","id":"28636603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI107
Number of Residues	2
Details	Modified residue: {"description":"Omega-N-methylarginine","evidences":[{"source":"PubMed","id":"24129315","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI108
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9CZX8","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI109
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"Q9CZX8","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI110
Number of Residues	2
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P62852","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI111
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25957688","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5A2Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AJ0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI112
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25957688","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5A2Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AJ0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FLX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LKS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI113
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25957688","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5A2Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AJ0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5LKS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI114
Number of Residues	23
Details	Zinc finger: {"description":"C4-type"}

Chain

Residue

Details

---

site_id	SWS_FT_FI115
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P63323","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI116
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P63276","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI117
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI118
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI119
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"36638793","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI120
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P60867","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI121
Number of Residues	14
Details	Region: {"description":"RNA gate","evidences":[{"source":"UniProtKB","id":"K7IM66","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI122
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"O70194","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI123
Number of Residues	342
Details	Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI124
Number of Residues	161
Details	Domain: {"description":"Helicase C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00542","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI125
Number of Residues	56
Details	Motif: {"description":"Q motif"}

Chain

Residue

Details

---

site_id	SWS_FT_FI126
Number of Residues	6
Details	Motif: {"description":"DEAD box"}

Chain

Residue

Details

---

site_id	SWS_FT_FI127
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI128
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P60843","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI129
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P60843","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---