Author results

1KSR
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THE REPEATING SEGMENTS OF THE F-ACTIN CROSS-LINKING GELATION FACTOR (ABP-120) HAVE AN IMMUNOGLOBULIN FOLD, NMR, 20 STRUCTURES
Descriptor:GELATION FACTOR
Authors:Fucini, P., Renner, C., Herberhold, C., Noegel, A.A., Holak, T.A.
Deposit date:1997-02-07
Release date:1997-08-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The repeating segments of the F-actin cross-linking gelation factor (ABP-120) have an immunoglobulin-like fold.
Nat.Struct.Biol., 4, 1997
1QFH
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DIMERIZATION OF GELATION FACTOR FROM DICTYOSTELIUM DISCOIDEUM: CRYSTAL STRUCTURE OF ROD DOMAINS 5 AND 6
Descriptor:PROTEIN (GELATION FACTOR)
Authors:Mccoy, A.J., Fucini, P., Noegel, A.A., Stewart, M.
Deposit date:1999-04-11
Release date:1999-04-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for dimerization of the Dictyostelium gelation factor (ABP120) rod.
Nat.Struct.Biol., 6, 1999
2D3O
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STRUCTURE OF RIBOSOME BINDING DOMAIN OF THE TRIGGER FACTOR ON THE 50S RIBOSOMAL SUBUNIT FROM D. RADIODURANS
Descriptor:23S RIBOSOMAL RNA, 50S RIBOSOMAL PROTEIN L23, 50S RIBOSOMAL PROTEIN L24, ...
Authors:Schluenzen, F., Wilson, D.N., Hansen, H.A., Tian, P., Harms, J.M., McInnes, S.J., Albrecht, R., Buerger, J., Wilbanks, S.M., Fucini, P.
Deposit date:2005-09-30
Release date:2005-12-06
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:The Binding Mode of the Trigger Factor on the Ribosome: Implications for Protein Folding and SRP Interaction
Structure, 13, 2005
5DM6
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CRYSTAL STRUCTURE OF THE 50S RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS
Descriptor:50S ribosomal protein L1, 50S ribosomal protein L2, 50S ribosomal protein L3, ...
Authors:Kaminishi, T., Schedlbauer, A., Ochoa-Lizarralde, B., Connell, S.R., Fucini, P.
Deposit date:2015-09-08
Release date:2015-11-11
Last modified:2016-02-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystallographic characterization of the ribosomal binding site and molecular mechanism of action of Hygromycin A.
Nucleic Acids Res., 43, 2015
5DM7
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CRYSTAL STRUCTURE OF THE 50S RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS IN COMPLEX WITH HYGROMYCIN A
Descriptor:50S ribosomal protein L1, 50S ribosomal protein L2, 50S ribosomal protein L3, ...
Authors:Kaminishi, T., Schedlbauer, A., Ochoa-Lizarralde, B., Connell, S.R., Fucini, P.
Deposit date:2015-09-08
Release date:2015-11-11
Last modified:2015-11-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystallographic characterization of the ribosomal binding site and molecular mechanism of action of Hygromycin A.
Nucleic Acids Res., 43, 2015
1P9X
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THE CRYSTAL STRUCTURE OF THE 50S LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS COMPLEXED WITH TELITHROMYCIN KETOLIDE ANTIBIOTIC
Descriptor:23S RIBOSOMAL RNA, TELITHROMYCIN
Authors:Berisio, R., Harms, J., Schluenzen, F., Zarivach, R., Hansen, H.A., Fucini, P., Yonath, A.
Deposit date:2003-05-13
Release date:2003-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural insight into the antibiotic action of telithromycin against resistant mutants
J.Bacteriol., 185, 2003
1SM1
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COMPLEX OF THE LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS WITH QUINUPRISTIN AND DALFOPRISTIN
Descriptor:23S RIBOSOMAL RNA, 50S RIBOSOMAL PROTEIN L33, 50S RIBOSOMAL PROTEIN L34, ...
Authors:Harms, J.M., Schluenzen, F., Fucini, P., Bartels, H., Yonath, A.
Deposit date:2004-03-08
Release date:2004-08-03
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (3.42 Å)
Cite:Alterations at the Peptidyl Transferase Centre of the Ribosome Induced by the Synergistic Action of the Streptogramins Dalfopristin and Quinupristin.
Bmc Biol., 2, 2004
1XBP
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INHIBITION OF PEPTIDE BOND FORMATION BY PLEUROMUTILINS: THE STRUCTURE OF THE 50S RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS IN COMPLEX WITH TIAMULIN
Descriptor:23S RIBOSOMAL RNA, 5S RIBOSOMAL RNA, 50S ribosomal protein L2, ...
Authors:Schluenzen, F., Pyetan, E., Fucini, P., Yonath, A., Harms, J.M.
Deposit date:2004-08-31
Release date:2005-03-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin.
Mol.Microbiol., 54, 2004
1Y69
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RRF DOMAIN I IN COMPLEX WITH THE 50S RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L16, ...
Authors:Wilson, D.N., Schluenzen, F., Harms, J.M., Yoshida, T., Ohkubo, T., Albrecht, R., Buerger, J., Kobayashi, Y., Fucini, P.
Deposit date:2004-12-04
Release date:2005-03-01
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (3.33 Å)
Cite:X-ray crystallography on ribosome recycling: mechanism of binding and action of RRF on the 50S ribosomal subunit
EMBO J., 24, 2005
2E5L
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A SNAPSHOT OF THE 30S RIBOSOMAL SUBUNIT CAPTURING MRNA VIA THE SHINE- DALGARNO INTERACTION
Descriptor:16S ribosomal RNA, 5'-R(*GP*AP*AP*AP*GP*A)-3', 30S ribosomal protein S2, ...
Authors:Kaminishi, T., Wilson, D.N., Takemoto, C., Harms, J.M., Kawazoe, M., Schluenzen, F., Hanawa-Suetsugu, K., Shirouzu, M., Fucini, P., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-12-21
Release date:2007-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A snapshot of the 30S ribosomal subunit capturing mRNA via the Shine-Dalgarno interaction
Structure, 15, 2007
2OM7
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STRUCTURAL BASIS FOR INTERACTION OF THE RIBOSOME WITH THE SWITCH REGIONS OF GTP-BOUND ELONGATION FACTORS
Descriptor:Fragment of 16S rRNA (h14), Fragment of 16S rRNA (h15), Fragment of 16S rRNA (h44), ...
Authors:Connell, S.R., Wilson, D.N., Rost, M., Schueler, M., Giesebrecht, J., Dabrowski, M., Mielke, T., Fucini, P., Spahn, C.M.T.
Deposit date:2007-01-21
Release date:2008-01-15
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors.
Mol.Cell, 25, 2007
2R1C
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COORDINATES OF THE THERMUS THERMOPHILUS RIBOSOME BINDING FACTOR A (RBFA) HOMOLOGY MODEL AS FITTED INTO THE CRYO-EM MAP OF A 30S-RBFA COMPLEX
Descriptor:Ribosome-binding factor A
Authors:Datta, P.P., Wilson, D.N., Kawazoe, M., Swami, N.K., Kaminishi, T., Sharma, M.R., Booth, T.M., Takemoto, C., Fucini, P., Yokoyama, S., Agrawal, R.K.
Deposit date:2007-08-22
Release date:2008-03-18
Last modified:2011-07-13
Method:ELECTRON MICROSCOPY (12.5 Å)
Cite:Structural aspects of RbfA action during small ribosomal subunit assembly.
Mol.Cell, 28, 2007
2R1G
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COORDINATES OF THE THERMUS THERMOPHILUS 30S COMPONENTS NEIGHBORING RBFA AS OBTAINED BY FITTING INTO THE CRYO-EM MAP OF A 30S-RBFA COMPLEX
Descriptor:16S RIBOSOMAL RNA HELIX 1, 16S RIBOSOMAL RNA HELIX 18, 16S RIBOSOMAL RNA HELIX 27, ...
Authors:Datta, P.P., Wilson, D.N., Kawazoe, M., Swami, N.K., Kaminishi, T., Sharma, M.R., Booth, T.M., Takemoto, C., Fucini, P., Yokoyama, S., Agrawal, R.K.
Deposit date:2007-08-22
Release date:2008-03-18
Last modified:2011-07-13
Method:ELECTRON MICROSCOPY (12.5 Å)
Cite:Structural aspects of RbfA action during small ribosomal subunit assembly.
Mol.Cell, 28, 2007
2ZJP
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THIOPEPTIDE ANTIBIOTIC NOSIHEPTIDE BOUND TO THE LARGE RIBOSOMAL SUBUNIT OF DEINOCOCCUS RADIODURANS
Descriptor:50S RIBOSOMAL PROTEIN L33, 50S RIBOSOMAL PROTEIN L34, 50S RIBOSOMAL PROTEIN L35, ...
Authors:Harms, J.M., Wilson, D.N., Schluenzen, F., Connell, S.R., Stachelhaus, T., Zaborowska, Z., Spahn, C.M.T., Fucini, P.
Deposit date:2008-03-07
Release date:2008-06-17
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Translational Regulation Via L11: Molecular Switches on the Ribosome Turned on and Off by Thiostrepton and Micrococcin.
Mol.Cell, 30, 2008
2ZJQ
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INTERACTION OF L7 WITH L11 INDUCED BY MICROCCOCIN BINDING TO THE DEINOCOCCUS RADIODURANS 50S SUBUNIT
Descriptor:ribosomal 23S RNA, ribosomal 5S RNA, 50S ribosomal protein L2, ...
Authors:Harms, J.M., Wilson, D.N., Schluenzen, F., Connell, S.R., Stachelhaus, T., Zaborowska, Z., Spahn, C.M.T., Fucini, P.
Deposit date:2008-03-08
Release date:2008-06-17
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin.
Mol.Cell, 30, 2008
2ZJR
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REFINED NATIVE STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT (50S) FROM DEINOCOCCUS RADIODURANS
Descriptor:ribosomal 23S RNA, ribosomal 5S RNA, 50S ribosomal protein L2, ...
Authors:Harms, J.M., Wilson, D.N., Schluenzen, F., Connell, S.R., Stachelhaus, T., Zaborowska, Z., Spahn, C.M.T., Fucini, P.
Deposit date:2008-03-08
Release date:2008-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin.
Mol.Cell, 30, 2008
3CF5
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THIOPEPTIDE ANTIBIOTIC THIOSTREPTON BOUND TO THE LARGE RIBOSOMAL SUBUNIT OF DEINOCOCCUS RADIODURANS
Descriptor:50S RIBOSOMAL PROTEIN L33, 50S RIBOSOMAL PROTEIN L34, 50S RIBOSOMAL PROTEIN L35, ...
Authors:Harms, J.M., Wilson, D.N., Schluenzen, F., Connell, S.R., Stachelhaus, T., Zaborowska, Z., Spahn, C.M.T., Fucini, P.
Deposit date:2008-03-02
Release date:2008-06-17
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Translational Regulation Via L11: Molecular Switches on the Ribosome Turned on and Off by Thiostrepton and Micrococcin.
Mol.Cell, 30, 2008
3DEG
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COMPLEX OF ELONGATING ESCHERICHIA COLI 70S RIBOSOME AND EF4(LEPA)-GMPPNP
Descriptor:A/L-tRNA, P-tRNA, 30S RNA helix 8, ...
Authors:Connell, S.R., Topf, M., Qin, Y., Wilson, D.N., Mielke, T., Fucini, P., Nierhaus, K.H., Spahn, C.M.T.
Deposit date:2008-06-10
Release date:2008-08-19
Last modified:2014-04-16
Method:ELECTRON MICROSCOPY (10.9 Å)
Cite:A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation
Nat.Struct.Mol.Biol., 15, 2008
3DLL
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THE OXAZOLIDINONE ANTIBIOTICS PERTURB THE RIBOSOMAL PEPTIDYL-TRANSFERASE CENTER AND EFFECT TRNA POSITIONING
Descriptor:rRNA-23S ribosomal RNA, rRNA-5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Wilson, D.N., Schluenzen, F., Harms, J.M., Starosta, A.L., Connell, S.R., Fucini, P.
Deposit date:2008-06-27
Release date:2008-09-16
Last modified:2015-07-22
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning
Proc.Natl.Acad.Sci.Usa, 105, 2008
4V5M
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TRNA TRANLOCATION ON THE 70S RIBOSOME: THE PRE-TRANSLOCATIONAL TRANSLOCATION INTERMEDIATE TI(PRE)
Descriptor:16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Ratje, A.H., Loerke, J., Mikolajka, A., Bruenner, M., Hildebrand, P.W., Starosta, A.L., Doenhoefer, A., Connell, S.R., Fucini, P., Mielke, T., Whitford, P.C., Onuchic, J.N., Yu, Y., Sanbonmatsu, K.Y., Hartmann, R.K., Penczek, P.A., Wilson, D.N., Spahn, C.M.T.
Deposit date:2010-10-01
Release date:2014-07-09
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Head Swivel on the Ribosome Facilitates Translocation by Means of Intra-Subunit tRNA Hybrid Sites.
Nature, 468, 2010
4V5N
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TRNA TRANSLOCATION ON THE 70S RIBOSOME: THE POST- TRANSLOCATIONAL TRANSLOCATION INTERMEDIATE TI(POST)
Descriptor:16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Ratje, A.H., Loerke, J., Mikolajka, A., Bruenner, M., Hildebrand, P.W., Starosta, A.L., Doenhoefer, A., Connell, S.R., Fucini, P., Mielke, T., Whitford, P.C., Onuchic, J.N., Yu, Y., Sanbonmatsu, K.Y., Hartmann, R.K., Penczek, P.A., Wilson, D.N., Spahn, C.M.T.
Deposit date:2010-10-21
Release date:2014-07-09
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Head Swivel on the Ribosome Facilitates Translocation by Means of Intra-Subunit tRNA Hybrid Sites.
Nature, 468, 2010
4V61
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HOMOLOGY MODEL FOR THE SPINACH CHLOROPLAST 30S SUBUNIT FITTED TO 9.4A CRYO-EM MAP OF THE 70S CHLORORIBOSOME.
Descriptor:16S rRNA, Ribosomal Protein S2, Ribosomal Protein S3, ...
Authors:Sharma, M.R., Wilson, D.N., Datta, P.P., Barat, C., Schluenzen, F., Fucini, P., Agrawal, R.K.
Deposit date:2007-11-09
Release date:2014-07-09
Last modified:2015-03-25
Method:ELECTRON MICROSCOPY (9.4 Å)
Cite:Cryo-EM study of the spinach chloroplast ribosome reveals the structural and functional roles of plastid-specific ribosomal proteins
Proc.Natl.Acad.Sci.Usa, 104, 2007
4YHH
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CRYSTAL STRUCTURE OF THE 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS IN COMPLEX WITH TIGECYCLINE
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Schedlbauer, A., Kaminishi, T., Ochoa-Lizarralde, B., Dhimole, N., Zhou, S., Lopez-Alonso, J.P., Connell, S.R., Fucini, P.
Deposit date:2015-02-27
Release date:2015-04-08
Last modified:2016-02-03
Method:X-RAY DIFFRACTION (3.417 Å)
Cite:Structural characterization of an alternative mode of tigecycline binding to the bacterial ribosome.
Antimicrob.Agents Chemother., 59, 2015
5IWA
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CRYSTAL STRUCTURE OF THE 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS IN COMPLEX WITH THE GE81112 PEPTIDE ANTIBIOTIC
Descriptor:30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
Authors:Schedlbauer, A., Kaminishi, T., Ochoa-Lizarralde, B., Chieko, N., Masahito, K., Takemoto, C., Yokoyama, S., Connell, S.R., Fucini, P.
Deposit date:2016-03-22
Release date:2016-04-27
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding.
Proc.Natl.Acad.Sci.USA, 113, 2016
5ME0
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STRUCTURE OF THE 30S PRE-INITIATION COMPLEX 1 (30S IC-1) STALLED BY GE81112
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Lopez-Alonso, J.P., Fabbretti, A., Kaminishi, T., Iturrioz, I., Brandi, L., Gil Carton, D., Gualerzi, C., Fucini, P., Connell, S.
Deposit date:2016-11-14
Release date:2017-01-11
Last modified:2018-11-21
Method:ELECTRON MICROSCOPY (13.5 Å)
Cite:Structure of a 30S pre-initiation complex stalled by GE81112 reveals structural parallels in bacterial and eukaryotic protein synthesis initiation pathways.
Nucleic Acids Res., 45, 2017
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