5IWA
Crystal structure of the 30S ribosomal subunit from Thermus thermophilus in complex with the GE81112 peptide antibiotic
Summary for 5IWA
| Entry DOI | 10.2210/pdb5iwa/pdb |
| Descriptor | 30S ribosomal protein S2, 30S ribosomal protein S11, 30S ribosomal protein S12, ... (24 entities in total) |
| Functional Keywords | protein synthesis, translation initiation, ribosome, antibiotic, translation |
| Biological source | Thermus thermophilus HB8 More |
| Total number of polymer chains | 21 |
| Total formula weight | 769656.87 |
| Authors | Schedlbauer, A.,Kaminishi, T.,Ochoa-Lizarralde, B.,Chieko, N.,Masahito, K.,Takemoto, C.,Yokoyama, S.,Connell, S.R.,Fucini, P. (deposition date: 2016-03-22, release date: 2016-04-27, Last modification date: 2024-01-10) |
| Primary citation | Fabbretti, A.,Schedlbauer, A.,Brandi, L.,Kaminishi, T.,Giuliodori, A.M.,Garofalo, R.,Ochoa-Lizarralde, B.,Takemoto, C.,Yokoyama, S.,Connell, S.R.,Gualerzi, C.O.,Fucini, P. Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding. Proc.Natl.Acad.Sci.USA, 113:E2286-E2295, 2016 Cited by PubMed: 27071098DOI: 10.1073/pnas.1521156113 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.5 Å) |
Structure validation
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