5IWA

Crystal structure of the 30S ribosomal subunit from Thermus thermophilus in complex with the GE81112 peptide antibiotic

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B	30S ribosomal protein S2	polymer	226	26159.3	1	UniProt (P80371) Pfam (PF00318) In PDB	Thermus thermophilus HB8
2	C	30S ribosomal protein S3	polymer	206	22862.4	1	UniProt (P80372) Pfam (PF07650) Pfam (PF00189) In PDB	Thermus thermophilus HB8
3	D	30S ribosomal protein S4	polymer	208	24242.3	1	UniProt (P80373) Pfam (PF00163) Pfam (PF01479) In PDB	Thermus thermophilus HB8
4	E	30S ribosomal protein S5	polymer	157	17067.8	1	UniProt (Q5SHQ5) Pfam (PF00333) Pfam (PF03719) In PDB	Thermus thermophilus HB8
5	F	30S ribosomal protein S6	polymer	101	11988.8	1	UniProt (Q5SLP8) Pfam (PF01250) In PDB	Thermus thermophilus HB8	TS9
6	G	30S ribosomal protein S7	polymer	155	17919.8	1	UniProt (P17291) Pfam (PF00177) In PDB	Thermus thermophilus HB8
7	H	30S ribosomal protein S8	polymer	138	15868.6	1	UniProt (Q5SHQ2) Pfam (PF00410) UniProt (by SIFTS) (P0DOY9) In PDB	Thermus thermophilus HB8
8	I	30S ribosomal protein S9	polymer	127	14279.4	1	UniProt (P80374) Pfam (PF00380) In PDB	Thermus thermophilus HB8
9	J	30S ribosomal protein S10	polymer	99	11398.3	1	UniProt (Q5SHN7) Pfam (PF00338) In PDB	Thermus thermophilus HB8
10	K	30S ribosomal protein S11	polymer	115	12161.8	1	UniProt (P80376) Pfam (PF00411) In PDB	Thermus thermophilus HB8
11	L	30S ribosomal protein S12	polymer	124	13804.3	1	UniProt (Q5SHN3) Pfam (PF00164) In PDB	Thermus thermophilus HB8
12	M	30S ribosomal protein S13	polymer	125	14207.7	1	UniProt (P80377) Pfam (PF00416) In PDB	Thermus thermophilus HB8
13	N	30S ribosomal protein S14 type Z	polymer	60	7027.5	1	UniProt (Q5SHQ1) Pfam (PF00253) UniProt (by SIFTS) (P0DOY6) In PDB	Thermus thermophilus HB8
14	O	30S ribosomal protein S15	polymer	88	10447.2	1	UniProt (Q5SJ76) Pfam (PF00312) In PDB	Thermus thermophilus HB8
15	P	30S ribosomal protein S16	polymer	85	10152.7	1	UniProt (Q5SJH3) Pfam (PF00886) In PDB	Thermus thermophilus HB8
16	Q	30S ribosomal protein S17	polymer	104	12194.5	1	UniProt (Q5SHP7) Pfam (PF00366) UniProt (by SIFTS) (P0DOY7) In PDB	Thermus thermophilus HB8
17	R	30S ribosomal protein S18	polymer	71	8313.0	1	UniProt (Q5SLQ0) Pfam (PF01084) In PDB	Thermus thermophilus HB8
18	S	30S ribosomal protein S19	polymer	83	9456.0	1	UniProt (Q5SHP2) Pfam (PF00203) In PDB	Thermus thermophilus HB8
19	T	30S ribosomal protein S20	polymer	103	11405.7	1	UniProt (P80380) Pfam (PF01649) In PDB	Thermus thermophilus HB8
20	V	30S ribosomal protein Thx	polymer	24	2960.5	1	UniProt (Q5SIH3) Pfam (PF17070) In PDB	Thermus thermophilus HB8	S31
21	A	16S ribosomal RNA	polymer	1509	489991.1	1	GenBank (55771382)	Thermus thermophilus HB8
22	A, O, S, B, E...	MAGNESIUM ION	non-polymer		24.3	204	Chemie (MG)
23	N, D	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
24	M	(2S,3S)-2-{[(2S)-3-(2-amino-1H-imidazol-5-yl)-2-{[(2S,4S)-5-(carbamoyloxy)-4-hydroxy-2-({[(2S,3S)-3-hydroxypiperidin-2-yl]carbonyl}amino)pentanoyl]amino}propanoyl]amino}-3-(2-chloro-1H-imidazol-5-yl)-3-hydroxypropanoic acid	non-polymer		659.0	1	Chemie (6EK)

Sequence modifications

A: 4 - 1532 (GenBank: 55771382)

PDB	External Database	Details
A 1	-	expression tag
A 2	-	expression tag
A 3	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	21
	Total formula weight	763908.8
Non-Polymers*	Number of molecules	207
	Total formula weight	5748.1
All*	Total formula weight	769656.9

*Water molecules are not included.