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5IWA

Crystal structure of the 30S ribosomal subunit from Thermus thermophilus in complex with the GE81112 peptide antibiotic

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B)
30S ribosomal protein S2polymer22626159.31UniProt (P80371)
Pfam (PF00318)
Thermus thermophilus HB8
2B
(C)
30S ribosomal protein S3polymer20622862.41UniProt (P80372)
Pfam (PF07650)
Pfam (PF00189)
Thermus thermophilus HB8
3C
(D)
30S ribosomal protein S4polymer20824242.31UniProt (P80373)
Pfam (PF00163)
Pfam (PF01479)
Thermus thermophilus HB8
4D
(E)
30S ribosomal protein S5polymer15717067.81UniProt (Q5SHQ5)
Pfam (PF00333)
Pfam (PF03719)
Thermus thermophilus HB8
5E
(F)
30S ribosomal protein S6polymer10111988.81UniProt (Q5SLP8)
Pfam (PF01250)
Thermus thermophilus HB8TS9
6F
(G)
30S ribosomal protein S7polymer15517919.81UniProt (P17291)
Pfam (PF00177)
Thermus thermophilus HB8
7G
(H)
30S ribosomal protein S8polymer13815868.61UniProt (Q5SHQ2)
Pfam (PF00410)
UniProt (by SIFTS) (P0DOY9)
Thermus thermophilus HB8
8H
(I)
30S ribosomal protein S9polymer12714279.41UniProt (P80374)
Pfam (PF00380)
Thermus thermophilus HB8
9I
(J)
30S ribosomal protein S10polymer9911398.31UniProt (Q5SHN7)
Pfam (PF00338)
Thermus thermophilus HB8
10J
(K)
30S ribosomal protein S11polymer11512161.81UniProt (P80376)
Pfam (PF00411)
Thermus thermophilus HB8
11K
(L)
30S ribosomal protein S12polymer12413804.31UniProt (Q5SHN3)
Pfam (PF00164)
Thermus thermophilus HB8
12L
(M)
30S ribosomal protein S13polymer12514207.71UniProt (P80377)
Pfam (PF00416)
Thermus thermophilus HB8
13M
(N)
30S ribosomal protein S14 type Zpolymer607027.51UniProt (Q5SHQ1)
Pfam (PF00253)
UniProt (by SIFTS) (P0DOY6)
Thermus thermophilus HB8
14N
(O)
30S ribosomal protein S15polymer8810447.21UniProt (Q5SJ76)
Pfam (PF00312)
Thermus thermophilus HB8
15O
(P)
30S ribosomal protein S16polymer8510152.71UniProt (Q5SJH3)
Pfam (PF00886)
Thermus thermophilus HB8
16P
(Q)
30S ribosomal protein S17polymer10412194.51UniProt (Q5SHP7)
Pfam (PF00366)
UniProt (by SIFTS) (P0DOY7)
Thermus thermophilus HB8
17Q
(R)
30S ribosomal protein S18polymer718313.01UniProt (Q5SLQ0)
Pfam (PF01084)
Thermus thermophilus HB8
18R
(S)
30S ribosomal protein S19polymer839456.01UniProt (Q5SHP2)
Pfam (PF00203)
Thermus thermophilus HB8
19S
(T)
30S ribosomal protein S20polymer10311405.71UniProt (P80380)
Pfam (PF01649)
Thermus thermophilus HB8
20T
(V)
30S ribosomal protein Thxpolymer242960.51UniProt (Q5SIH3)
Pfam (PF17070)
Thermus thermophilus HB8S31
21U
(A)
16S ribosomal RNApolymer1509489991.11GenBank (55771382)Thermus thermophilus HB8
22AB, AC, AD, AE, AF...
(A, O, S, B, E...)
MAGNESIUM IONnon-polymer24.3204Chemie (MG)
23BA, W
(N, D)
ZINC IONnon-polymer65.42Chemie (ZN)
24AA
(M)
(2S,3S)-2-{[(2S)-3-(2-amino-1H-imidazol-5-yl)-2-{[(2S,4S)-5-(carbamoyloxy)-4-hydroxy-2-({[(2S,3S)-3-hydroxypiperidin-2-yl]carbonyl}amino)pentanoyl]amino}propanoyl]amino}-3-(2-chloro-1H-imidazol-5-yl)-3-hydroxypropanoic acidnon-polymer659.01Chemie (6EK)
Sequence modifications
A: 4 - 1532 (GenBank: 55771382)
PDBExternal DatabaseDetails
A 1-expression tag
A 2-expression tag
A 3-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains21
Total formula weight763908.8
Non-Polymers*Number of molecules207
Total formula weight5748.1
All*Total formula weight769656.9
*Water molecules are not included.

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PDB entries from 2025-06-18

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