Author results

3GB8
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CRYSTAL STRUCTURE OF CRM1/SNURPORTIN-1 COMPLEX
Descriptor:Exportin-1, Snurportin-1
Authors:Dong, X., Biswas, A., Suel, K.E., Jackson, L.K., Martinez, R., Gu, H., Chook, Y.M.
Deposit date:2009-02-19
Release date:2009-03-31
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for leucine-rich nuclear export signal recognition by CRM1.
Nature, 458, 2009
1Z9M
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CRYSTAL STRUCTURE OF NECTIN-LIKE MOLECULE-1 PROTEIN DOMAIN 1
Descriptor:GAPA225
Authors:Dong, X., Xu, F., Gong, Y., Gao, J., Lin, P., Chen, T., Peng, Y., Qiang, B., Yuan, J., Peng, X., Rao, Z.
Deposit date:2005-04-03
Release date:2006-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of the V Domain of Human Nectin-like Molecule-1/Syncam3/Tsll1/Igsf4b, a Neural Tissue-specific Immunoglobulin-like Cell-Cell Adhesion Molecule
J.Biol.Chem., 281, 2006
1WQL
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CUMENE DIOXYGENASE (CUMA1A2) FROM PSEUDOMONAS FLUORESCENS IP01
Descriptor:iron-sulfur protein large subunit of cumene dioxygenase, ethylbenzene dioxygenase small subunit, FE (II) ION, ...
Authors:Dong, X., Fushinobu, S., Fukuda, E., Terada, T., Nakamura, S., Shimizu, K., Nojiri, H., Omori, T., Shoun, H., Wakagi, T.
Deposit date:2004-09-30
Release date:2005-03-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of the Terminal Oxygenase Component of Cumene Dioxygenase from Pseudomonas fluorescens IP01
J.BACTERIOL., 187, 2005
1VS3
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CRYSTAL STRUCTURE OF THE TRNA PSEUDOURIDINE SYNTHASE TRUA FROM THERMUS THERMOPHILUS HB8
Descriptor:tRNA pseudouridine synthase A
Authors:Dong, X., Bessho, Y., Shirouzu, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-06-28
Release date:2006-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure of tRNA Pseudouridine Synthase TruA from Thermus thermophilus HB8
Rna Biol., 3, 2006
2DUD
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CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL SINGLE-STRANDED DNA-BINDING PROTEIN(HMTSSB)
Descriptor:Single-stranded DNA-binding protein
Authors:Dong, X., Bessho, Y., Shirouzu, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-07-21
Release date:2007-01-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of human mitochondrial single-stranded DNA-binding protein(hmtSSB)
To be Published
2EGV
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CRYSTAL STRUCTURE OF RRNA METHYLTRANSFERASE WITH SAM LIGAND
Descriptor:UPF0088 protein aq_165, S-ADENOSYLMETHIONINE
Authors:Dong, X., Shirouzu, M., Bessho, Y., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-02
Release date:2007-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal structure of rRNA methyltransferase with SAM ligand
To be Published
2EGW
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CRYSTAL STRUCTURE OF RRNA METHYLTRANSFERASE WITH SAH LIGAND
Descriptor:UPF0088 protein aq_165, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Dong, X., Shirouzu, M., Bessho, Y., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-02
Release date:2007-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of rRNA methyltransferase with SAH ligand
To be Published
2MVU
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SOLUTION STRUCTURE OF THE 3,7-DIOXO-OCTYL ACTINORHODIN ACYL CARRIER PROTEIN FROM STREPTOMYCES COELICOLOR
Descriptor:Actinorhodin polyketide synthase acyl carrier protein, N~3~-{(2S)-4-[(dihydroxyphosphanyl)oxy]-2-hydroxy-3,3-dimethylbutanoyl}-N-{2-[(3,7-dioxooctyl)sulfanyl]ethyl}-beta-alaninamide
Authors:Dong, X., Bailey, C., Williams, C., Crosby, J., Simpson, T.J., Willis, C.L., Crump, M.P.
Deposit date:2014-10-15
Release date:2015-10-21
Method:SOLUTION NMR
Cite:ACP-ligand recognition: Selection of derivatized aromatic biosynthetic intermediates
To be Published
2MVV
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SOLUTION STRUCTURE OF THE 5-PHENYL-3-OXO-PENTYL ACTINORHODIN ACYL CARRIER PROTEIN FROM STREPTOMYCES COELICOLOR
Descriptor:Actinorhodin polyketide synthase acyl carrier protein, N~3~-{(2S)-4-[(dihydroxyphosphanyl)oxy]-2-hydroxy-3,3-dimethylbutanoyl}-N-{2-[(3-oxo-5-phenylpentyl)sulfanyl]ethyl}-beta-alaninamide
Authors:Dong, X., Bailey, C., Williams, C., Crosby, J., Simpson, T.J., Willis, C.L., Crump, M.P.
Deposit date:2014-10-15
Release date:2015-10-21
Method:SOLUTION NMR
Cite:ACP-ligand recognition: Selection of derivatized aromatic biosynthetic intermediates
To be Published
4G1E
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CRYSTAL STRUCTURE OF INTEGRIN ALPHA V BETA 3 WITH COIL-COILED TAG.
Descriptor:Integrin alpha-V, Integrin beta-3, CALCIUM ION, ...
Authors:Dong, X., Mi, L., Zhu, J., Wang, W., Luo, B., Springer, T.A.
Deposit date:2012-07-10
Release date:2012-12-05
Method:X-RAY DIFFRACTION (3 Å)
Cite:AlphaV Beta3 Integrin Crystal Structures and their Functional Implications
Biochemistry, 51, 2012
4UM8
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CRYSTAL STRUCTURE OF ALPHA V BETA 6
Descriptor:INTEGRIN ALPHA-V, INTEGRIN BETA-6, CHLORIDE ION, ...
Authors:Dong, X., Springer, T.A.
Deposit date:2014-05-15
Release date:2014-11-12
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (2.852 Å)
Cite:Structural Determinants of Integrin Beta-Subunit Specificity for Latent Tgf-Beta
Nat.Struct.Mol.Biol., 21, 2014
4UM9
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CRYSTAL STRUCTURE OF ALPHA V BETA 6 WITH PEPTIDE
Descriptor:INTEGRIN ALPHA-V, INTEGRIN BETA-6, TRANSFORMING GROWTH FACTOR BETA 3, ...
Authors:Dong, X., Springer, T.A.
Deposit date:2014-05-15
Release date:2014-11-12
Last modified:2016-03-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Determinants of Integrin Beta-Subunit Specificity for Latent Tgf-Beta
Nat.Struct.Mol.Biol., 21, 2014
5FFG
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CRYSTAL STRUCTURE OF INTEGRIN ALPHA V BETA 6 HEAD
Descriptor:Integrin alpha-V, Integrin beta-6, CALCIUM ION, ...
Authors:Dong, X., Springer, T.A.
Deposit date:2015-12-18
Release date:2017-01-25
Last modified:2017-02-15
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Force interacts with macromolecular structure in activation of TGF-beta.
Nature, 542, 2017
5FFO
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INTEGRIN ALPHA V BETA 6 IN COMPLEX WITH PRO-TGF-BETA
Descriptor:Integrin alpha-V, Integrin beta-6, Transforming growth factor beta-1, ...
Authors:Dong, X., Zhao, B., Springer, T.A.
Deposit date:2015-12-18
Release date:2017-01-25
Last modified:2017-02-15
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Force interacts with macromolecular structure in activation of TGF-beta.
Nature, 542, 2017
5XK4
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RETRACTED STATE OF S65-PHOSPHORYLATED UBIQUITIN
Descriptor:Polyubiquitin-B
Authors:Dong, X., Gong, Z., Qin, L.Y., Ran, M.L., Zhang, C.L., Liu, K., Liu, Z., Zhang, W.P., Tang, C.
Deposit date:2017-05-05
Release date:2017-06-28
Last modified:2017-07-12
Method:SOLUTION NMR
Cite:Ubiquitin S65 phosphorylation engenders a pH-sensitive conformational switch
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5Z2S
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CRYSTAL STRUCTURE OF DUX4-HD2 DOMAIN
Descriptor:Double homeobox protein 4
Authors:Dong, X., Zhang, W., Wu, H., Huang, J., Zhang, M., Wang, P., Zhang, H., Chen, Z., Chen, S., Meng, G.
Deposit date:2018-01-03
Release date:2018-04-04
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis of DUX4/IGH-driven transactivation.
Leukemia, 32, 2018
5Z2T
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CRYSTAL STRUCTURE OF DNA-BOUND DUX4-HD2
Descriptor:Double homeobox protein 4, 5'-D(*TP*TP*CP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*TP*T)-3', 5'-D(P*AP*AP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*GP*T)-3'
Authors:Dong, X., Zhang, W., Wu, H., Huang, J., Zhang, M., Wang, P., Zhang, H., Chen, Z., Chen, S., Meng, G.
Deposit date:2018-01-04
Release date:2018-04-04
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (2.623 Å)
Cite:Structural basis of DUX4/IGH-driven transactivation.
Leukemia, 32, 2018
6A8R
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CRYSTAL STRUCTURE OF DUX4 HD2 DOMAIN ASSOCIATED WITH ERG DNA BINDING SITE
Descriptor:Double homeobox protein 4, DNA (5'-D(P*TP*GP*AP*TP*GP*AP*GP*AP*TP*T)-3'), DNA (5'-D(P*AP*AP*TP*CP*TP*CP*AP*TP*CP*A)-3')
Authors:Dong, X., Zhang, H., Cheng, N., Meng, G.
Deposit date:2018-07-10
Release date:2018-10-24
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:DUX4HD2-DNAERGstructure reveals new insight into DUX4-Responsive-Element.
Leukemia, 33, 2019
6N29
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CRYSTAL STRUCTURE OF MONOMERIC VON WILLEBRAND FACTOR D`D3 ASSEMBLY
Descriptor:von Willebrand factor, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ...
Authors:Dong, X., Arndt, J.W., Springer, T.A.
Deposit date:2018-11-12
Release date:2019-01-23
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The von Willebrand factor D'D3 assembly and structural principles for factor VIII binding and concatemer biogenesis.
Blood, 133, 2019
5VBT
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CRYSTAL STRUCTURE OF A HIGHLY SPECIFIC AND POTENT USP7 UBIQUITIN VARIANT INHIBITOR
Descriptor:UBH04
Authors:DONG, A., DONG, X., LIU, L., GUO, Y., LI, Y., ZHANG, W., WALKER, J.R., SIDHU, S., Bountra, C., Arrowsmith, C.H., Edwards, A.M., TONG, Y., Structural Genomics Consortium (SGC)
Deposit date:2017-03-30
Release date:2017-06-07
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Crystal structure of a highly specific and potent USP7 ubiquitin variant inhibitor
to be published
5YZ9
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ZINC FINGER DOMAIN OF METTL3-METTL14 N6-METHYLADENOSINE METHYLTRANSFERASE
Descriptor:N6-adenosine-methyltransferase catalytic subunit, ZINC ION
Authors:Dong, X., Tang, C., Gong, Z., Yin, P., Huang, J.B.
Deposit date:2017-12-13
Release date:2018-03-28
Last modified:2019-03-27
Method:SOLUTION NMR, SOLUTION SCATTERING
Cite:Solution structure of the RNA recognition domain of METTL3-METTL14 N6-methyladenosine methyltransferase.
Protein Cell, 10, 2019
2L22
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MUPIROCIN DIDOMAIN ACP
Descriptor:Mupirocin didomain Acyl Carrier Protein
Authors:Dong, X., Williams, C., Crump, M.P., Wattana-amorn, P.
Deposit date:2010-08-10
Release date:2012-02-15
Last modified:2013-11-06
Method:SOLUTION NMR
Cite:A conserved motif flags acyl carrier proteins for beta-branching in polyketide synthesis.
Nat.Chem.Biol., 9, 2013
3EBM
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CRYSTAL STRUCTURE OF HUMAN TRANSLATIONALLY CONTROLLED TUMOUR ASSOCIATED PROTEIN (HTCTP) MUTANT E12V
Descriptor:Translationally-controlled tumor protein
Authors:Yang, B., Dong, X., Zhong, C., Ding, J.
Deposit date:2008-08-28
Release date:2009-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular basis of the acceleration of the GDP-GTP exchange of human ras homolog enriched in brain by human translationally controlled tumor protein.
J.Biol.Chem., 284, 2009
3PPV
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CRYSTAL STRUCTURE OF AN ENGINEERED VWF A2 DOMAIN (N1493C AND C1670S)
Descriptor:von Willebrand factor, SULFATE ION, CALCIUM ION
Authors:Zhou, M., Dong, X., Zhong, C., Ding, J.
Deposit date:2010-11-25
Release date:2011-05-04
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13
Blood, 117, 2011
3PPW
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CRYSTAL STRUCTURE OF THE D1596A MUTANT OF AN ENGINEERED VWF A2 DOMAIN (N1493C AND C1670S)
Descriptor:von Willebrand factor, SODIUM ION
Authors:Zhou, M., Dong, X., Zhong, C., Ding, J.
Deposit date:2010-11-25
Release date:2011-05-04
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13
Blood, 117, 2011
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