5FFG

Crystal structure of integrin alpha V beta 6 head

Summary for 5FFG

Entry DOI	10.2210/pdb5ffg/pdb
Descriptor	Integrin alpha-V, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... (12 entities in total)
Functional Keywords	integrin, cell adhesion
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	100088.75
Authors	Dong, X.,Springer, T.A. (deposition date: 2015-12-18, release date: 2017-01-25, Last modification date: 2020-07-29)
Primary citation	Dong, X.,Zhao, B.,Iacob, R.E.,Zhu, J.,Koksal, A.C.,Lu, C.,Engen, J.R.,Springer, T.A. Force interacts with macromolecular structure in activation of TGF-beta. Nature, 542:55-59, 2017 Cited by PubMed: 28117447 DOI: 10.1038/nature21035 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation