6N29

Crystal structure of monomeric von Willebrand Factor D`D3 assembly

Summary for 6N29

Descriptorvon Willebrand factor, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ... (5 entities in total)
Functional Keywordsvon willebrand factor, blood clotting
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total molecular weight108098.18
Authors
Dong, X.,Arndt, J.W.,Springer, T.A. (deposition date: 2018-11-12, release date: 2019-01-23, Last modification date: 2019-04-17)
Primary citation
Dong, X.,Leksa, N.C.,Chhabra, E.S.,Arndt, J.W.,Lu, Q.,Knockenhauer, K.E.,Peters, R.T.,Springer, T.A.
The von Willebrand factor D'D3 assembly and structural principles for factor VIII binding and concatemer biogenesis.
Blood, 133:1523-1533, 2019
PubMed: 30642920 (PDB entries with the same primary citation)
DOI: 10.1182/blood-2018-10-876300
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2454 0.2% 0.8% 9.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6n29
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Molmil generated image of 6n29
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Molmil generated image of 6n29
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More Biological unit images

Molmil generated image of 6n29
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Molmil generated image of 6n29
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Molmil generated image of 6n29
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(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (6n29.pdb1.gz [164.5 KB])
Coordinate files for Biological unit (6n29.pdb2.gz [163.12 KB])