Author results

2BCK
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CRYSTAL STRUCTURE OF HLA-A*2402 COMPLEXED WITH A TELOMERASE PEPTIDE
Descriptor:HLA class I histocompatibility antigen, A-24 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Jakobsen, B.K., Cole, D.K., Gao, G.F.
Deposit date:2005-10-19
Release date:2006-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of HLA-A*2402 complexed with a telomerase peptide.
Eur.J.Immunol., 36, 2006
2HP4
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COMPUTATIONAL DESIGN AND CRYSTAL STRUCTURE OF AN ENHANCED AFFINITY MUTANT HUMAN CD8-ALPHA-ALPHA CO-RECEPTOR
Descriptor:T-cell surface glycoprotein CD8 alpha chain, SULFATE ION, GLYCEROL
Authors:Rizkallah, P.J., Cole, D.K., Jakobsen, B.K., Boulter, J.M., Glick, M., Gao, G.F.
Deposit date:2006-07-17
Release date:2007-02-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Computational design and crystal structure of an enhanced affinity mutant human CD8 alphaalpha coreceptor
Proteins, 67, 2007
2Q3A
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CRYSTAL STRUCTURE OF RHESUS MACAQUE CD8 ALPHA-ALPHA HOMODIMER
Descriptor:CD8
Authors:Peng, H., Chen, Y., Zong, L., Gao, F., Liu, Y., Gao, G.F.
Deposit date:2007-05-30
Release date:2008-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of Rhesus Macaque CD8 Homodimer Sheds the Lights on the Molecular Basis of Rhesus Macaque MHC class I with CD8 Complex
To be Published
3HG1
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GERMLINE-GOVERNED RECOGNITION OF A CANCER EPITOPE BY AN IMMUNODOMINANT HUMAN T CELL RECEPTOR
Descriptor:MHC class I antigen, Beta-2-microglobulin, CANCER/MART-1, ...
Authors:Cole, D.K., Yuan, F., Rizkallah, P.J., Miles, J.J., Gostick, E., Price, D.A., Gao, G.F., Jakobsen, B.K., Sewell, A.K.
Deposit date:2009-05-13
Release date:2009-07-28
Last modified:2014-04-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:Germ line-governed recognition of a cancer epitope by an immunodominant human T-cell receptor.
J.Biol.Chem., 284, 2009
3H7B
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HUMAN CLASS I MHC HLA-A2 IN COMPLEX WITH THE TEL1P PEPTIDE
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Borbulevych, O.Y., Baker, B.M.
Deposit date:2009-04-24
Release date:2010-01-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility.
Immunity, 31, 2009
3H9H
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HUMAN CLASS I MHC HLA-A2(A150P) IN COMPLEX WITH THE TEL1P PEPTIDE
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Borbulevych, O.Y., Baker, B.M.
Deposit date:2009-04-30
Release date:2010-01-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility.
Immunity, 31, 2009
3H9S
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THE COMPLEX BETWEEN TCR A6 AND HUMAN CLASS I MHC HLA-A2 WITH THE BOUND TEL1P PEPTIDE
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Borbulevych, O.Y., Baker, B.M.
Deposit date:2009-04-30
Release date:2010-01-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility.
Immunity, 31, 2009
3IXA
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HUMAN CLASS I MHC HLA-A2(A150P) IN COMPLEX WITH THE TAX PEPTIDE
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Borbulevych, O.Y., Baker, B.M.
Deposit date:2009-09-03
Release date:2010-01-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility.
Immunity, 31, 2009
3O4L
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GENETIC AND STRUCTURAL BASIS FOR SELECTION OF A UBIQUITOUS T CELL RECEPTOR DEPLOYED IN EPSTEIN-BARR VIRUS
Descriptor:MHC class I antigen, Beta-2-microglobulin, BSLF2/BMLF1 protein, ...
Authors:Miles, J.J., Bulek, A.M., Cole, D.K., Gostick, E., Schauenburg, J.A., Dolton, G., Venturi, V., Davenport, M.P., Tan, M.P., Burrows, S.R., Wooldridge, L., Price, D.A., Rizkallah, P.J., Sewell, A.K.
Deposit date:2010-07-27
Release date:2011-01-12
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection.
Plos Pathog., 6, 2010
3NTN
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CRYSTAL STRUCTURE OF USPA1 HEAD AND NECK DOMAIN FROM MORAXELLA CATARRHALIS
Descriptor:UspA1, SULFATE ION, CHLORIDE ION, ...
Authors:Conners, R., Zaccai, N., Agnew, C., Burton, N., Brady, R.L.
Deposit date:2010-07-05
Release date:2011-07-06
Last modified:2011-09-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Correlation of in situ mechanosensitive responses of the Moraxella catarrhalis adhesin UspA1 with fibronectin and receptor CEACAM1 binding.
Proc.Natl.Acad.Sci.USA, 108, 2011
3PR7
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MULTI-FUNCTIONAL AND MECHANOSENSITIVE RECEPTOR BINDING ACTIVITY OF THE MORAXELLA CATARRHALIS ADHESIN USPA1
Descriptor:UspA1
Authors:Agnew, C.R.J., Zaccai, N.R., Conners, R., Brady, R.L.
Deposit date:2010-11-29
Release date:2011-09-07
Last modified:2011-09-28
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Correlation of in situ mechanosensitive responses of the Moraxella catarrhalis adhesin UspA1 with fibronectin and receptor CEACAM1 binding.
Proc.Natl.Acad.Sci.USA, 108, 2011
3UTP
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1E6 TCR SPECIFIC FOR HLA-A*0201-ALWGPDPAAA
Descriptor:1E6 TCR alpha chain, 1E6 TCR beta chain, GLYCEROL, ...
Authors:Rizkallah, P.J., Cole, D.K., Sewell, A.K., Bulek, A.M.
Deposit date:2011-11-26
Release date:2012-01-25
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (2.574 Å)
Cite:Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13, 2012
3UTQ
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HUMAN HLA-A*0201-ALWGPDPAAA
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Sewell, A.K., Bulek, A.M.
Deposit date:2011-11-26
Release date:2012-01-25
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13, 2012
3UTS
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1E6-A*0201-ALWGPDPAAA COMPLEX, MONOCLINIC
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Sewell, A.K., Bulek, A.M.
Deposit date:2011-11-26
Release date:2012-01-25
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (2.712 Å)
Cite:Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13, 2012
3UTT
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1E6-A*0201-ALWGPDPAAA COMPLEX, TRICLINIC
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Sewell, A.K., Bulek, A.M., Rossjohn, J., Gras, S.
Deposit date:2011-11-26
Release date:2012-01-25
Last modified:2012-03-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13, 2012
4GKN
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A2-MHC COMPLEX CARRYING FATGIGIITV
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Sewell, A.K., Rizkallah, P.J., Cole, D.K., Wooldridge, L., Price, D.A.
Deposit date:2012-08-13
Release date:2012-09-12
Last modified:2012-11-14
Method:X-RAY DIFFRACTION (2.753 Å)
Cite:T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting.
J.Biol.Chem., 287, 2012
4GKS
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A2-MHC COMPLEX CARRYING FLTGIGIITV
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Sewell, A.K., Rizkallah, P.J., Cole, D.K., Wooldridge, L., Price, D.A.
Deposit date:2012-08-13
Release date:2012-09-12
Last modified:2012-11-14
Method:X-RAY DIFFRACTION (2.346 Å)
Cite:T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting.
J.Biol.Chem., 287, 2012
4GKZ
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HA1.7, A MHC CLASS II RESTRICTED TCR SPECIFIC FOR HAEMAGGLUTININ
Descriptor:Alpha chain of Class II TCR, Beta Chain of Class II TCR, 1,2-ETHANEDIOL, ...
Authors:Holland, C.J., Rizkallah, P.J., Cole, D.K., Sewell, A.K., Godkin, A.J.
Deposit date:2012-08-13
Release date:2012-11-07
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Minimal conformational plasticity enables TCR cross-reactivity to different MHC class II heterodimers.
Sci Rep, 2, 2012
4I4W
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PEPTIDE LENGTH DETERMINES THE OUTCOME OF T CELL RECEPTOR/PEPTIDE-MHCI ENGAGEMENT
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Wooldridge, L., Cole, D.K.
Deposit date:2012-11-28
Release date:2013-01-02
Last modified:2015-11-25
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Peptide length determines the outcome of TCR/peptide-MHCI engagement.
Blood, 121, 2013
4JFD
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PRESERVATION OF PEPTIDE SPECIFICITY DURING TCR-MHC CONTACT DOMINATED AFFINITY ENHANCEMENT OF A MELANOMA-SPECIFIC TCR
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Madura, F., Sewell, A.K.
Deposit date:2013-02-28
Release date:2013-05-29
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288, 2013
4JFE
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PRESERVATION OF PEPTIDE SPECIFICITY DURING TCR-MHC CONTACT DOMINATED AFFINITY ENHANCEMENT OF A MELANOMA-SPECIFIC TCR
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Madura, F., Sewell, A.K.
Deposit date:2013-02-28
Release date:2013-05-29
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288, 2013
4JFF
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PRESERVATION OF PEPTIDE SPECIFICITY DURING TCR-MHC CONTACT DOMINATED AFFINITY ENHANCEMENT OF A MELANOMA-SPECIFIC TCR
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Madura, F., Sewell, A.K.
Deposit date:2013-02-28
Release date:2013-05-29
Last modified:2014-04-02
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288, 2013
4JFH
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HIGH AFFINITY ALPHA24-BETA17 T CELL RECEPTOR FOR A2 HLA-MELANOMA PEPTIDE COMPLEX
Descriptor:alpha24 TCR allele, beta17 TCR allele, 1,2-ETHANEDIOL, ...
Authors:Rizkallah, P.J., Cole, D.K., Madura, F., Sewell, A.K.
Deposit date:2013-02-28
Release date:2013-05-29
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288, 2013
4JFO
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A2 HLA COMPLEX WITH E1A HETEROCLITIC VARIANT OF MELANOMA PEPTIDE
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Madura, F., Sewell, A.K., Baker, B.M.
Deposit date:2013-02-28
Release date:2013-05-29
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288, 2013
4JFP
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A2 HLA COMPLEX WITH G4A HETEROCLITIC VARIANT OF MELANOMA PEPTIDE
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Madura, F., Sewell, A.K.
Deposit date:2013-02-28
Release date:2013-05-29
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288, 2013