HLA class I histocompatibility antigen

Summary for 5C09
Related3UTP 3UTQ 3UTS 3UTT 5C06 5C07 5C08 5C0A 5C0B 5C0C 5C0D 5C0E 5C0F 5C0G 5C0H 5C0I 5C0J 5HYJ
DescriptorHLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Marker peptide, ... (7 entities in total)
Functional Keywordsimmuno, hla-a02, 1e6-tcr, cross-reactivity, immune system
Biological sourceHomo sapiens (Human)
Cellular locationMembrane; Single-pass type I membrane protein: P01892
Secreted : P61769
Total number of polymer chains10
Total formula weight191608.89
Rizkallah, P.J.,Bulek, A.M.,Cole, D.K.,Sewell, A.K. (deposition date: 2015-06-12, release date: 2016-05-04, Last modification date: 2016-06-08)
Primary citationBulek, A.M.,Cole, D.K.,Dolton, G.,Fuller, A.,Jothikumar, P.,Miles, J.J.,Peakman, M.,Rittase, W.,Rizkallah, P.J.,Rossjohn, J.,Schauenberg, A.J.,Sewell, A.K.,Skowera, A.,Szomolay, B.,Trimby, A.,Wooldridge, L.,Zhu, C.
Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126:2191-2204, 2016
PubMed: 27183389
DOI: 110.1172/JCI85679
PDB entries with the same primary citation
Experimental method
Structure validation
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PDB entries from 2021-06-23