5MEP

Human Leukocyte Antigen A02 presenting ILGKFLHWL

Summary for 5MEP
DescriptorHLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ILE-LEU-GLY-LYS-PHE-LEU-HIS-TRP-LEU, ... (6 entities in total)
Functional Keywordshla a02, hlaa, mhc, immuno, telomerase, immune system
Biological sourceHomo sapiens (Human)
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Cellular locationMembrane; Single-pass type I membrane protein: P01892
Secreted . Note=(Microbial infection) In the presence of M: P61769
Total number of polymer chains6
Total formula weight90696.97
Authors
Rizkallah, P.J.,Cole, D.K.,Lloyd, A.,Crowther, M.,Sewell, A.K. (deposition date: 2016-11-16, release date: 2016-12-07, Last modification date: 2017-02-01)
Primary citationBeck, K.,Bulek, A.M.,Clement, M.,Cole, D.K.,Crowther, M.D.,Dolton, G.,Ekeruche-Makinde, J.,Fuller, A.,Laugel, B.,Lloyd, A.,Miles, J.J.,Rizkallah, P.J.,Schauenburg, A.J.,Sewell, A.K.,Wall, A.,Wooldridge, L.,van den Berg, H.A.
Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
J. Biol. Chem., 292:802-813, 2017
PubMed: 27903649
DOI: 110.1074/jbc.M116.741603
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.71 Å)
Structure validation
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PDB entries from 2021-06-16