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1H8X
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DOMAIN-SWAPPED DIMER OF A HUMAN PANCREATIC RIBONUCLEASE VARIANT
Descriptor:RIBONUCLEASE 1
Authors:Canals, A., Pous, J., Guasch, A., Benito, A., Ribo, M., Vilanova, M., Coll, M.
Deposit date:2001-02-16
Release date:2002-02-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Structure of an Engineered Domain-Swapped Ribonuclease Dimer and its Implications for the Evolution of Proteins Toward Oligomerization
Structure, 9, 2001
1NQ6
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF XYLANASE A FROM STREPTOMYCES HALSTEDII JM8
Descriptor:Xys1, MAGNESIUM ION
Authors:Canals, A., Vega, M.C., Gomis-Ruth, F.X., Santamaria, R.I., Coll, M.
Deposit date:2003-01-21
Release date:2004-01-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structure of xylanase Xys1delta from Streptomyces halstedii.
Acta Crystallogr.,Sect.D, 59, 2003
1Z3F
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STRUCTURE OF ELLIPTICINE IN COMPLEX WITH A 6-BP DNA
Descriptor:5'-D(*CP*GP*AP*TP*CP*G)-3', ELLIPTICINE, COBALT (II) ION
Authors:Canals, A., Purciolas, M., Aymami, J., Coll, M.
Deposit date:2005-03-12
Release date:2005-07-19
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The anticancer agent ellipticine unwinds DNA by intercalative binding in an orientation parallel to base pairs.
Acta Crystallogr.,Sect.D, 61, 2005
3L0O
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STRUCTURE OF RNA-FREE RHO TRANSCRIPTION TERMINATION FACTOR FROM THERMOTOGA MARITIMA
Descriptor:Transcription termination factor rho, URANYL (VI) ION, SULFATE ION, ...
Authors:Canals, A., Uson, I., Coll, M.
Deposit date:2009-12-10
Release date:2010-05-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The Structure of RNA-Free Rho Termination Factor Indicates a Dynamic Mechanism of Transcript Capture
J.Mol.Biol., 400, 2010
4MNB
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CRYSTAL STRUCTURE OF A COMPLEX BETWEEN THE MARINE ANTICANCER DRUG VARIOLIN B AND DNA
Descriptor:5'-D(*CP*GP*TP*AP*CP*G)-3', 9-amino-5-(2-aminopyrimidin-4-yl)pyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidin-4-ol, COBALT HEXAMMINE(III), ...
Authors:Canals, A., Arribas-Bosacoma, R., Alvarez, M., Albericio, F., Aymami, J., Coll, M.
Deposit date:2013-09-10
Release date:2015-03-11
Last modified:2017-02-22
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Intercalative DNA binding of the marine anticancer drug variolin B.
Sci Rep, 7, 2017
3O76
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1.8 ANGSTROMS MOLECULAR STRUCTURE OF MOUSE LIVER GLUTATHIONE S-TRANSFERASE MUTANT C47A COMPLEXED WITH S-(P-NITROBENZYL)GLUTATHIONE
Descriptor:Glutathione S-transferase P 1, S-(P-NITROBENZYL)GLUTATHIONE
Authors:Canals, A., Coll, M.
Deposit date:2010-07-30
Release date:2011-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Site-directed mutagenesis of mouse glutathione transferase P1-1 unlocks masked cooperativity, introduces a novel mechanism for 'ping pong' kinetic behaviour, and provides further structural evidence for participation of a water molecule in proton abstraction from glutathione.
Febs J., 278, 2011
1DZA
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3-D STRUCTURE OF A HP-RNASE
Descriptor:RIBONUCLEASE 1
Authors:Pous, J., Canals, A., Terzyan, S.S., Guasch, A., Benito, A., Ribo, M., Vilanova, M., Coll, M.
Deposit date:2000-02-21
Release date:2001-02-16
Last modified:2012-11-07
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Three-Dimensional Structure of a Human Pancreatic Ribonuclease Variant, a Step Forward in the Design of Cytotoxic Ribonucleases
J.Mol.Biol., 303, 2000
4JIU
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CRYSTAL STRUCTURE OF THE METALLOPEPTIDASE ZYMOGEN OF PYROCOCCUS ABYSSI ABYLYSIN
Descriptor:Proabylysin, ZINC ION, GLYCEROL
Authors:Lopez-Pelegrin, M., Cerda-Costa, N., Martinez-Jimenez, F., Cintas-Pedrola, A., Canals, A., Peinado, J.R., Marti-Renom, M.A., Lopez-Otin, C., Arolas, J.L., Gomis-Ruth, F.X.
Deposit date:2013-03-07
Release date:2013-06-12
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:A novel family of soluble minimal scaffolds provides structural insight into the catalytic domains of integral membrane metallopeptidases
J.Biol.Chem., 288, 2013
4JIX
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CRYSTAL STRUCTURE OF THE METALLOPEPTIDASE ZYMOGEN OF METHANOCALDOCOCCUS JANNASCHII JANNALYSIN
Descriptor:Projannalysin, ZINC ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Lopez-Pelegrin, M., Cerda-Costa, N., Martinez-Jimenez, F., Cintas-Pedrola, A., Canals, A., Peinado, J.R., Marti-Renom, M.A., Lopez-Otin, C., Arolas, J.L., Gomis-Ruth, F.X.
Deposit date:2013-03-07
Release date:2013-06-12
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:A novel family of soluble minimal scaffolds provides structural insight into the catalytic domains of integral membrane metallopeptidases
J.Biol.Chem., 288, 2013
3T72
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PHOB(E)-SIGMA70(4)-(RNAP-BETHA-FLAP-TIP-HELIX)-DNA TRANSCRIPTION ACTIVATION SUB-COMPLEX
Descriptor:Phosphate regulon transcriptional regulatory protein phoB, PHO BOX DNA (STRAND 1), PHO BOX DNA (STRAND 2), ...
Authors:Blanco, A.G., Canals, A., Bernues, J., Sola, M., Coll, M.
Deposit date:2011-07-29
Release date:2011-09-21
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (4.33 Å)
Cite:The Structure of a Transcription Activation Sub-Complex Reveals How Sigma-70 is Recruited to PhoB Promoters
Embo J., 2011
4ICU
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UBIQUITIN-LIKE DOMAIN OF HUMAN TUBULIN FOLDING COFACTOR E - CRYSTAL FROM A
Descriptor:Tubulin-specific chaperone E
Authors:Janowski, R., Boutin, M., Zabala, J.C., Coll, M.
Deposit date:2012-12-11
Release date:2014-06-18
Last modified:2016-06-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure of the complex between alpha-tubulin, TBCE and TBCB reveals a tubulin dimer dissociation mechanism.
J.Cell.Sci., 128, 2015
4ICV
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UBIQUITIN-LIKE DOMAIN OF HUMAN TUBULIN FOLDING COFACTOR E - CRYSTAL FORM B
Descriptor:Tubulin-specific chaperone E, PRASEODYMIUM ION
Authors:Janowski, R., Boutin, M., Zabala, J.C., Coll, M.
Deposit date:2012-12-11
Release date:2014-06-18
Last modified:2016-06-22
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The structure of the complex between alpha-tubulin, TBCE and TBCB reveals a tubulin dimer dissociation mechanism.
J.Cell.Sci., 128, 2015