Author results

1H8X
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DOMAIN-SWAPPED DIMER OF A HUMAN PANCREATIC RIBONUCLEASE VARIANT
Descriptor:RIBONUCLEASE 1
Authors:Canals, A., Pous, J., Guasch, A., Benito, A., Ribo, M., Vilanova, M., Coll, M.
Deposit date:2001-02-16
Release date:2002-02-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Structure of an Engineered Domain-Swapped Ribonuclease Dimer and its Implications for the Evolution of Proteins Toward Oligomerization
Structure, 9, 2001
2ERM
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SOLUTION STRUCTURE OF A BIOLOGICALLY ACTIVE HUMAN FGF-1 MONOMER, COMPLEXED TO A HEXASACCHARIDE HEPARIN-ANALOGUE
Descriptor:Heparin-binding growth factor 1, 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-acetamido-2-deoxy-6-O-sulfo-alpha-D-glucopyranose-(1-4)-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, ISOPROPYL ALCOHOL
Authors:Canales, A., Lozano, R., Nieto, P.M., Martin-Lomas, M., Gimenez-Gallego, G., Jimenez-Barbero, J.
Deposit date:2005-10-25
Release date:2006-10-03
Last modified:2020-07-29
Method:SOLUTION NMR
Cite:Solution NMR structure of a human FGF-1 monomer, activated by a hexasaccharide heparin-analogue.
Febs J., 273, 2006
1NQ6
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF XYLANASE A FROM STREPTOMYCES HALSTEDII JM8
Descriptor:Xys1, MAGNESIUM ION
Authors:Canals, A., Vega, M.C., Gomis-Ruth, F.X., Santamaria, R.I., Coll, M.
Deposit date:2003-01-21
Release date:2004-01-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structure of xylanase Xys1delta from Streptomyces halstedii.
Acta Crystallogr.,Sect.D, 59, 2003
1Z3F
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STRUCTURE OF ELLIPTICINE IN COMPLEX WITH A 6-BP DNA
Descriptor:5'-D(*CP*GP*AP*TP*CP*G)-3', ELLIPTICINE, COBALT (II) ION
Authors:Canals, A., Purciolas, M., Aymami, J., Coll, M.
Deposit date:2005-03-12
Release date:2005-07-19
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The anticancer agent ellipticine unwinds DNA by intercalative binding in an orientation parallel to base pairs.
Acta Crystallogr.,Sect.D, 61, 2005
3L0O
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STRUCTURE OF RNA-FREE RHO TRANSCRIPTION TERMINATION FACTOR FROM THERMOTOGA MARITIMA
Descriptor:Transcription termination factor rho, URANYL (VI) ION, SULFATE ION, ...
Authors:Canals, A., Uson, I., Coll, M.
Deposit date:2009-12-10
Release date:2010-05-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The Structure of RNA-Free Rho Termination Factor Indicates a Dynamic Mechanism of Transcript Capture
J.Mol.Biol., 400, 2010
4MNB
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CRYSTAL STRUCTURE OF A COMPLEX BETWEEN THE MARINE ANTICANCER DRUG VARIOLIN B AND DNA
Descriptor:5'-D(*CP*GP*TP*AP*CP*G)-3', 9-amino-5-(2-aminopyrimidin-4-yl)pyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidin-4-ol, COBALT HEXAMMINE(III), ...
Authors:Canals, A., Arribas-Bosacoma, R., Alvarez, M., Albericio, F., Aymami, J., Coll, M.
Deposit date:2013-09-10
Release date:2015-03-11
Last modified:2017-02-22
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Intercalative DNA binding of the marine anticancer drug variolin B.
Sci Rep, 7, 2017
3O76
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1.8 ANGSTROMS MOLECULAR STRUCTURE OF MOUSE LIVER GLUTATHIONE S-TRANSFERASE MUTANT C47A COMPLEXED WITH S-(P-NITROBENZYL)GLUTATHIONE
Descriptor:Glutathione S-transferase P 1, S-(P-NITROBENZYL)GLUTATHIONE
Authors:Canals, A., Coll, M.
Deposit date:2010-07-30
Release date:2011-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Site-directed mutagenesis of mouse glutathione transferase P1-1 unlocks masked cooperativity, introduces a novel mechanism for 'ping pong' kinetic behaviour, and provides further structural evidence for participation of a water molecule in proton abstraction from glutathione.
Febs J., 278, 2011
1DZA
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3-D STRUCTURE OF A HP-RNASE
Descriptor:RIBONUCLEASE 1
Authors:Pous, J., Canals, A., Terzyan, S.S., Guasch, A., Benito, A., Ribo, M., Vilanova, M., Coll, M.
Deposit date:2000-02-21
Release date:2001-02-16
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Three-Dimensional Structure of a Human Pancreatic Ribonuclease Variant, a Step Forward in the Design of Cytotoxic Ribonucleases
J.Mol.Biol., 303, 2000
4JIU
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CRYSTAL STRUCTURE OF THE METALLOPEPTIDASE ZYMOGEN OF PYROCOCCUS ABYSSI ABYLYSIN
Descriptor:Proabylysin, ZINC ION, GLYCEROL
Authors:Lopez-Pelegrin, M., Cerda-Costa, N., Martinez-Jimenez, F., Cintas-Pedrola, A., Canals, A., Peinado, J.R., Marti-Renom, M.A., Lopez-Otin, C., Arolas, J.L., Gomis-Ruth, F.X.
Deposit date:2013-03-07
Release date:2013-06-12
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:A novel family of soluble minimal scaffolds provides structural insight into the catalytic domains of integral membrane metallopeptidases
J.Biol.Chem., 288, 2013
4JIX
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CRYSTAL STRUCTURE OF THE METALLOPEPTIDASE ZYMOGEN OF METHANOCALDOCOCCUS JANNASCHII JANNALYSIN
Descriptor:Projannalysin, ZINC ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Lopez-Pelegrin, M., Cerda-Costa, N., Martinez-Jimenez, F., Cintas-Pedrola, A., Canals, A., Peinado, J.R., Marti-Renom, M.A., Lopez-Otin, C., Arolas, J.L., Gomis-Ruth, F.X.
Deposit date:2013-03-07
Release date:2013-06-12
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:A novel family of soluble minimal scaffolds provides structural insight into the catalytic domains of integral membrane metallopeptidases
J.Biol.Chem., 288, 2013
2LVZ
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SOLUTION STRUCTURE OF A EOSINOPHIL CATIONIC PROTEIN-TRISACCHARIDE HEPARIN MIMETIC COMPLEX
Descriptor:Eosinophil cationic protein, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-propan-2-yl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside
Authors:Garcia Mayoral, M., Canales, A., Diaz, D., Lopez Prados, J., Moussaoui, M., de Paz, J., Angulo, J., Nieto, P., Jimenez Barbero, J., Boix, E., Bruix, M.
Deposit date:2012-07-17
Release date:2013-07-31
Last modified:2020-07-29
Method:SOLUTION NMR
Cite:Insights into the glycosaminoglycan-mediated cytotoxic mechanism of eosinophil cationic protein revealed by NMR.
Acs Chem.Biol., 8, 2013
3T72
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PHOB(E)-SIGMA70(4)-(RNAP-BETHA-FLAP-TIP-HELIX)-DNA TRANSCRIPTION ACTIVATION SUB-COMPLEX
Descriptor:Phosphate regulon transcriptional regulatory protein phoB, PHO BOX DNA (STRAND 1), PHO BOX DNA (STRAND 2), ...
Authors:Blanco, A.G., Canals, A., Bernues, J., Sola, M., Coll, M.
Deposit date:2011-07-29
Release date:2011-09-21
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (4.33 Å)
Cite:The Structure of a Transcription Activation Sub-Complex Reveals How Sigma-70 is Recruited to PhoB Promoters
Embo J., 2011
6Y6D
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TUBULIN-7-AMINONOSCAPINE COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Oliva, M.A., Prota, A.E., Rodriguez-Salarichs, J., Gu, W., Bennani, Y.L., Jimenez-Barbero, J., Canales, A., Steinmetz, M.O., Diaz, J.F.
Deposit date:2020-02-26
Release date:2020-07-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of noscapine activation for tubulin binding.
J.Med.Chem., 2020
2N0X
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THREE DIMENSIONAL STRUCTURE OF EPI-X4, A HUMAN ALBUMIN-DERIVED PEPTIDE THAT REGULATES INNATE IMMUNITY THROUGH THE CXCR4/CXCL12 CHEMOTACTIC AXIS AND ANTAGONIZES HIV-1 ENTRY
Descriptor:Serum albumin
Authors:Perez-Castells, J., Canales, A., Jimenez-Barbero, J., Gimenez-Gallego, G.
Deposit date:2015-03-18
Release date:2015-04-29
Last modified:2015-05-20
Method:SOLUTION NMR
Cite:Discovery and characterization of an endogenous CXCR4 antagonist.
Cell Rep, 11, 2015
6QI4
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NCS-1 BOUND TO A LIGAND
Descriptor:Neuronal calcium sensor 1, CALCIUM ION, HEXAETHYLENE GLYCOL, ...
Authors:Sanchez-Barrena, M.J., Blanco-Gabella, P.
Deposit date:2019-01-17
Release date:2019-07-17
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Insights into real-time chemical processes in a calcium sensor protein-directed dynamic library.
Nat Commun, 10, 2019
5NJH
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TRIAZOLOPYRIMIDINES STABILIZE MICROTUBULES BY BINDING TO THE VINCA INHIBITOR SITE OF TUBULIN
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Sharma, A., Calvo, G.S., Prota, A.E., Diaz, J.F., Steinmetz, M.O.
Deposit date:2017-03-28
Release date:2017-06-21
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.394 Å)
Cite:Triazolopyrimidines Are Microtubule-Stabilizing Agents that Bind the Vinca Inhibitor Site of Tubulin.
Cell Chem Biol, 24, 2017
4ICU
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UBIQUITIN-LIKE DOMAIN OF HUMAN TUBULIN FOLDING COFACTOR E - CRYSTAL FROM A
Descriptor:Tubulin-specific chaperone E
Authors:Janowski, R., Boutin, M., Zabala, J.C., Coll, M.
Deposit date:2012-12-11
Release date:2014-06-18
Last modified:2016-06-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure of the complex between alpha-tubulin, TBCE and TBCB reveals a tubulin dimer dissociation mechanism.
J.Cell.Sci., 128, 2015
4ICV
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UBIQUITIN-LIKE DOMAIN OF HUMAN TUBULIN FOLDING COFACTOR E - CRYSTAL FORM B
Descriptor:Tubulin-specific chaperone E, PRASEODYMIUM ION
Authors:Janowski, R., Boutin, M., Zabala, J.C., Coll, M.
Deposit date:2012-12-11
Release date:2014-06-18
Last modified:2016-06-22
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The structure of the complex between alpha-tubulin, TBCE and TBCB reveals a tubulin dimer dissociation mechanism.
J.Cell.Sci., 128, 2015
167132
PDB entries from 2020-07-29