3O76

1.8 Angstroms molecular structure of mouse liver glutathione S-transferase mutant C47A complexed with S-(P-nitrobenzyl)glutathione

Summary for 3O76

Entry DOI	10.2210/pdb3o76/pdb
Related	1GLQ
Descriptor	Glutathione S-transferase P 1, S-(P-NITROBENZYL)GLUTATHIONE (3 entities in total)
Functional Keywords	transferase(glutathione), transferase
Biological source	Mus musculus (mouse)
Total number of polymer chains	2
Total formula weight	47828.68
Authors	Canals, A.,Coll, M. (deposition date: 2010-07-30, release date: 2011-06-15, Last modification date: 2023-09-06)
Primary citation	McManus, G.,Costa, M.,Canals, A.,Coll, M.,Mantle, T.J. Site-directed mutagenesis of mouse glutathione transferase P1-1 unlocks masked cooperativity, introduces a novel mechanism for 'ping pong' kinetic behaviour, and provides further structural evidence for participation of a water molecule in proton abstraction from glutathione. Febs J., 278:273-281, 2011 Cited by PubMed: 21134126 DOI: 10.1111/j.1742-4658.2010.07944.x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.77 Å)

Structure validation