8B4C
ToxR bacterial transcriptional regulator bound to 20 bp toxT promoter DNA
Summary for 8B4C
Entry DOI | 10.2210/pdb8b4c/pdb |
Descriptor | Cholera toxin transcriptional activator, DNA (20-MER), ... (4 entities in total) |
Functional Keywords | bacterial transcription, activation complex, dna binding protein |
Biological source | Vibrio cholerae More |
Total number of polymer chains | 3 |
Total formula weight | 24965.49 |
Authors | Canals, A.,Pieretti, S.,Muriel, M.,El Yaman, N.,Fabrega-Ferrer, M.,Perez-Luque, R.,Krukonis, E.S.,Coll, M. (deposition date: 2022-09-20, release date: 2023-08-09, Last modification date: 2024-06-19) |
Primary citation | Canals, A.,Pieretti, S.,Muriel-Masanes, M.,El Yaman, N.,Plecha, S.C.,Thomson, J.J.,Fabrega-Ferrer, M.,Perez-Luque, R.,Krukonis, E.S.,Coll, M. ToxR activates the Vibrio cholerae virulence genes by tethering DNA to the membrane through versatile binding to multiple sites. Proc.Natl.Acad.Sci.USA, 120:e2304378120-e2304378120, 2023 Cited by PubMed: 37428913DOI: 10.1073/pnas.2304378120 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.07 Å) |
Structure validation
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