1Z3F

Structure of ellipticine in complex with a 6-bp DNA

Summary for 1Z3F

Descriptor5'-D(*CP*GP*AP*TP*CP*G)-3', ELLIPTICINE, COBALT (II) ION, ... (4 entities in total)
Functional Keywordsanticancer, dna binding, drug design, ellipticine, intercalator, dna
Total number of polymer chains2
Total molecular weight4289.86
Authors
Canals, A.,Purciolas, M.,Aymami, J.,Coll, M. (deposition date: 2005-03-12, release date: 2005-07-19, Last modification date: 2017-10-11)
Primary citation
Canals, A.,Purciolas, M.,Aymami, J.,Coll, M.
The anticancer agent ellipticine unwinds DNA by intercalative binding in an orientation parallel to base pairs.
Acta Crystallogr.,Sect.D, 61:1009-1012, 2005
PubMed: 15983425 (PDB entries with the same primary citation)
DOI: 10.1107/S0907444905015404
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.5 Å)
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Structure validation

RfreeClashscoreRSRZ outliers0.256110MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload