8B4B

ToxR bacterial transcriptional regulator bound to 19 bp ompU promoter DNA

Summary for 8B4B

Entry DOI	10.2210/pdb8b4b/pdb
Descriptor	DNA (19-MER), Cholera toxin transcriptional activator, CADMIUM ION, ... (6 entities in total)
Functional Keywords	bacterial transcription, activation complex, dna binding protein
Biological source	Vibrio cholerae More
Total number of polymer chains	6
Total formula weight	65709.86
Authors	Canals, A.,Pieretti, S.,Muriel, M.,El Yaman, N.,Fabrega-Ferrer, M.,Perez-Luque, R.,Krukonis, E.S.,Coll, M. (deposition date: 2022-09-20, release date: 2023-08-09)
Primary citation	Canals, A.,Pieretti, S.,Muriel-Masanes, M.,El Yaman, N.,Plecha, S.C.,Thomson, J.J.,Fabrega-Ferrer, M.,Perez-Luque, R.,Krukonis, E.S.,Coll, M. ToxR activates the Vibrio cholerae virulence genes by tethering DNA to the membrane through versatile binding to multiple sites. Proc.Natl.Acad.Sci.USA, 120:e2304378120-e2304378120, 2023 Cited by PubMed: 37428913 DOI: 10.1073/pnas.2304378120 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation