1H8X

Domain-swapped Dimer of a Human Pancreatic Ribonuclease Variant

Summary for 1H8X

Related1E21
DescriptorRIBONUCLEASE 1 (2 entities in total)
Functional Keywordshydrolase, ribonuclease, rnase, human pancreatic ribonuclease, domain- swapped dimer
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationSecreted P07998
Total number of polymer chains2
Total molecular weight28908.34
Authors
Canals, A.,Pous, J.,Guasch, A.,Benito, A.,Ribo, M.,Vilanova, M.,Coll, M. (deposition date: 2001-02-16, release date: 2002-02-14, Last modification date: 2011-07-13)
Primary citation
Canals, A.,Pous, J.,Guasch, A.,Benito, A.,Ribo, M.,Vilanova, M.,Coll, M.
The Structure of an Engineered Domain-Swapped Ribonuclease Dimer and its Implications for the Evolution of Proteins Toward Oligomerization
Structure, 9:967-, 2001
PubMed: 11591351 (PDB entries with the same primary citation)
DOI: 10.1016/S0969-2126(01)00659-1
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers120.4%1.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution