Author results

6FAB
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THREE-DIMENSIONAL STRUCTURE OF MURINE ANTI-P-AZOPHENYLARSONATE FAB 36-71. 1. X-RAY CRYSTALLOGRAPHY, SITE-DIRECTED MUTAGENESIS, AND MODELING OF THE COMPLEX WITH HAPTEN
Descriptor:IGG1-KAPPA 36-71 FAB (LIGHT CHAIN), IGG1-KAPPA 36-71 FAB (HEAVY CHAIN)
Authors:Strong, R.K., Rose, D.R., Petsko, G.A., Sharon, J., Margolies, M.N.
Deposit date:1991-01-17
Release date:1993-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Three-dimensional structure of murine anti-p-azophenylarsonate Fab 36-71. 1. X-ray crystallography, site-directed mutagenesis, and modeling of the complex with hapten.
Biochemistry, 30, 1991
1KPR
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THE HUMAN NON-CLASSICAL MAJOR HISTOCOMPATIBILITY COMPLEX MOLECULE HLA-E
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN, BETA-2-MICROGLOBULIN, ...
Authors:Holmes, M.A., Strong, R.K.
Deposit date:2002-01-02
Release date:2003-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:HLA-E allelic variants: Correlating differential expression, peptide affinities, crystal structures and thermal stabilities
J.Biol.Chem., 278, 2003
1KTL
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THE HUMAN NON-CLASSICAL MAJOR HISTOCOMPATIBILITY COMPLEX MOLECULE HLA-E
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN, BETA-2-MICROGLOBULIN, ...
Authors:Holmes, M.A., Strong, R.K.
Deposit date:2002-01-16
Release date:2003-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:HLA-E allelic variants: Correlating differential expression, peptide affinities, crystal structures and thermal stabilities
J.Biol.Chem., 278, 2003
3CII
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STRUCTURE OF NKG2A/CD94 BOUND TO HLA-E
Descriptor:HLA class I histocompatibility antigen, alpha chain E, Beta-2-microglobulin, ...
Authors:Strong, R.K., Kaiser, B.K., Pizarro, J.C.
Deposit date:2008-03-11
Release date:2008-05-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.41 Å)
Cite:Structural basis for NKG2A/CD94 recognition of HLA-E.
Proc.Natl.Acad.Sci.Usa, 105, 2008
1HYR
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CRYSTAL STRUCTURE OF HUMAN MICA IN COMPLEX WITH NATURAL KILLER CELL RECEPTOR NKG2D
Descriptor:NKG2-D TYPE II INTEGRAL MEMBRANE PROTEIN, MHC CLASS I CHAIN-RELATED PROTEIN A
Authors:Li, P., Strong, R.K.
Deposit date:2001-01-21
Release date:2001-05-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Complex structure of the activating immunoreceptor NKG2D and its MHC class I-like ligand MICA.
Nat.Immunol., 2, 2001
1L6M
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NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN IS A NOVEL BACTERIOSTATIC AGENT THAT INTERFERES WITH SIDEROPHORE-MEDIATED IRON ACQUISITION
Descriptor:Neutrophil gelatinase-associated lipocalin, FE (III) ION, SULFATE ION, ...
Authors:Goetz, D.H., Borregaard, N., Bluhm, M.E., Raymond, K.N., Strong, R.K.
Deposit date:2002-03-11
Release date:2003-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Neutrophil Lipocalin NGAL is a Bacteriostatic Agent that Interferes with Siderophore-mediated Iron Acquisition
Mol.Cell, 10, 2002
3OMZ
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CRYSTAL STRUCTURE OF MICA-SPECIFIC HUMAN GAMMA DELTA T CELL RECEPTOR
Descriptor:human Vdelta1 gamma delta T cell receptor delta1A/B-3
Authors:Xu, B., Holmes, M.A., Strong, R.K.
Deposit date:2010-08-27
Release date:2011-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Crystal structure of a {gamma}{delta} T-cell receptor specific for the human MHC class I homolog MICA.
Proc.Natl.Acad.Sci.USA, 108, 2011
1DFV
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CRYSTAL STRUCTURE OF HUMAN NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN MONOMER
Descriptor:HUMAN NEUTROPHIL GELATINASE, N-ACETYL-D-GLUCOSAMINE, SULFATE ION, ...
Authors:Goetz, D.H., Willie, S.T., Armen, R.S., Bratt, T., Borregaard, N., Strong, R.K.
Deposit date:1999-11-22
Release date:2000-03-06
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Ligand preference inferred from the structure of neutrophil gelatinase associated lipocalin
Biochemistry, 39, 2000
1JE6
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STRUCTURE OF THE MHC CLASS I HOMOLOG MICB
Descriptor:MHC class I chain-related protein, SULFATE ION
Authors:Holmes, M.A., Li, P., Strong, R.K.
Deposit date:2001-06-15
Release date:2002-08-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural studies of allelic diversity of the MHC class I homolog MIC-B, a stress-inducible ligand for the activating immunoreceptor NKG2D.
J.Immunol., 169, 2002
1JFM
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CRYSTAL STRUCTURE OF MURINE NK CELL LIGAND RAE-1 BETA
Descriptor:retinoic acid early transcript beta
Authors:Li, P., Strong, R.K.
Deposit date:2001-06-21
Release date:2002-02-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal structures of RAE-1beta and its complex with the activating immunoreceptor NKG2D.
Immunity, 16, 2002
1JFQ
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ANTIGEN-BINDING FRAGMENT OF THE MURINE ANTI-PHENYLARSONATE ANTIBODY 36-71, "FAB 36-71"
Descriptor:ANTIGEN-BINDING FRAGMENT OF ANTI-PHENYLARSONATE ANTIBODY
Authors:Parhami-Seren, B., Viswanathan, M., Strong, R.K., Margolies, M.N.
Deposit date:2001-06-21
Release date:2002-02-27
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of mutants of high-affinity and low-affinity p-azophenylarsonate-specific antibodies generated by alanine scanning of heavy chain complementarity-determining region 2.
J.Immunol., 167, 2001
1MPU
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CRYSTAL STRUCTURE OF THE FREE HUMAN NKG2D IMMUNORECEPTOR
Descriptor:NKG2-D type II integral membrane protein, PHOSPHATE ION
Authors:McFarland, B.J., Kortemme, T., Baker, D., Strong, R.K.
Deposit date:2002-09-12
Release date:2003-04-15
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Symmetry Recognizing Asymmetry: Analysis of the Interactions between the C-Type Lectin-like Immunoreceptor NKG2D and MHC Class I-like Ligands
Structure, 11, 2003
1QQS
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NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN HOMODIMER
Descriptor:NEUTROPHIL GELATINASE, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Goetz, D.H., Willie, S.T., Armen, R., Bratt, T., Borregaard, N., Strong, R.K.
Deposit date:1999-06-07
Release date:2000-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ligand preference inferred from the structure of neutrophil gelatinase associated lipocalin
Biochemistry, 39, 2000
1X71
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CRYSTAL STRUCTURE OF SIDEROCALIN (NGAL, LIPOCALIN 2) COMPLEXED WITH TRENCAM-3,2-HOPO, A CEPABACTIN ANALOGUE
Descriptor:Neutrophil gelatinase-associated lipocalin, FE (III) ION, 2,3-DIHYDROXYBENZAMIDE
Authors:Holmes, M.A., Paulsene, W., Jide, X., Ratledge, C., Strong, R.K.
Deposit date:2004-08-12
Release date:2005-01-18
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Siderocalin (Lcn 2) Also Binds Carboxymycobactins, Potentially Defending against Mycobacterial Infections through Iron Sequestration
Structure, 13, 2005
1X89
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CRYSTAL STRUCTURE OF SIDEROCALIN (NGAL, LIPOCALIN 2) COMPLEXED WITH CARBOXYMYCOBACTIN S
Descriptor:Neutrophil gelatinase-associated lipocalin, CARBOXYMYCOBACTIN S
Authors:Holmes, M.A., Paulsene, W., Jide, X., Ratledge, C., Strong, R.K.
Deposit date:2004-08-17
Release date:2005-01-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Siderocalin (Lcn 2) Also Binds Carboxymycobactins, Potentially Defending against Mycobacterial Infections through Iron Sequestration
Structure, 13, 2005
1X8U
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CRYSTAL STRUCTURE OF SIDEROCALIN (NGAL, LIPOCALIN 2) COMPLEXED WITH CARBOXYMYCOBACTIN T
Descriptor:Neutrophil gelatinase-associated lipocalin, CARBOXYMYCOBACTIN T
Authors:Holmes, M.A., Paulsene, W., Jide, X., Ratledge, C., Strong, R.K.
Deposit date:2004-08-18
Release date:2005-01-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Siderocalin (Lcn 2) Also Binds Carboxymycobactins, Potentially Defending against Mycobacterial Infections through Iron Sequestration
Structure, 13, 2005
2P1Y
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1.B2.D9, A BISPECIFIC ALPHA/BETA TCR
Descriptor:bispecific alpha/beta TCR
Authors:McBeth, C., Pizarro, J.C., Strong, R.K.
Deposit date:2007-03-06
Release date:2008-02-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:A new twist in TCR diversity revealed by a forbidden alphabeta TCR.
J.Mol.Biol., 375, 2008
2P24
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I-AU/MBP125-135
Descriptor:H-2 class II histocompatibility antigen, A-U alpha chain, A-U beta chain
Authors:McBeth, C., Strong, R.K.
Deposit date:2007-03-06
Release date:2008-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A new twist in TCR diversity revealed by a forbidden alphabeta TCR.
J.Mol.Biol., 375, 2008
3BY0
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CRYSTAL STRUCTURE OF SIDEROCALIN (NGAL, LIPOCALIN 2) W79A-R81A COMPLEXED WITH FERRIC ENTEROBACTIN
Descriptor:Neutrophil gelatinase-associated lipocalin, FE (III) ION, SULFATE ION, ...
Authors:Clifton, M.C., Pizzaro, J.C., Strong, R.K.
Deposit date:2008-01-15
Release date:2008-09-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.572 Å)
Cite:The siderocalin/enterobactin interaction: a link between mammalian immunity and bacterial iron transport.
J.Am.Chem.Soc., 130, 2008
3CBC
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CRYSTAL STRUCTURE OF SIDEROCALIN (NGAL, LIPOCALIN 2) Y106F COMPLEXED WITH FERRIC ENTEROBACTIN
Descriptor:Neutrophil gelatinase-associated lipocalin, SULFATE ION, SODIUM ION, ...
Authors:Clifton, M.C., Pizaro, J.C., Strong, R.K.
Deposit date:2008-02-21
Release date:2008-09-09
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:The siderocalin/enterobactin interaction: a link between mammalian immunity and bacterial iron transport.
J.Am.Chem.Soc., 130, 2008
3CMP
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CRYSTAL STRUCTURE OF SIDEROCALIN (NGAL, LIPOCALIN 2) K125A MUTANT COMPLEXED WITH FERRIC ENTEROBACTIN
Descriptor:Neutrophil gelatinase-associated lipocalin, FE (III) ION, SODIUM ION, ...
Authors:Clifton, M.C., Strong, R.K.
Deposit date:2008-03-24
Release date:2009-05-12
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Parsing the functional specificity of Siderocalin / Lipocalin 2 / NGAL for siderophores and related small-molecule ligands
To be Published
3FW4
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CRYSTAL STRUCTURE OF SIDEROCALIN (NGAL, LIPOCALIN 2) COMPLEXED WITH FERRIC CATECHOL
Descriptor:Neutrophil gelatinase-associated lipocalin, FE (III) ION, CATECHOL, ...
Authors:Clifton, M.C., Strong, R.K.
Deposit date:2009-01-16
Release date:2010-05-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Iron traffics in circulation bound to a siderocalin (Ngal)-catechol complex.
Nat.Chem.Biol., 6, 2010
3FW5
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CRYSTAL STRUCTURE OF SIDEROCALIN (NGAL, LIPOCALIN 2) COMPLEXED WITH FERRIC 4-METHYL-CATECHOL
Descriptor:Neutrophil gelatinase-associated lipocalin, FE (III) ION, 4-METHYLCATECHOL, ...
Authors:Clifton, M.C., Strong, R.K.
Deposit date:2009-01-16
Release date:2010-05-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Iron traffics in circulation bound to a siderocalin (Ngal)-catechol complex.
Nat.Chem.Biol., 6, 2010
3RU8
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STRUCTURE OF AN HIV EPITOPE SCAFFOLD IN COMPLEX WITH NEUTRALIZING ANTIBODY B12 FAB
Descriptor:Epitope Scaffold 2bodx43, Antibody b12, Heavy Chain, ...
Authors:Carrico, C.T.D., Strong, R.K.
Deposit date:2011-05-04
Release date:2011-11-02
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold.
Science, 334, 2011
3S26
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CRYSTAL STRUCTURE OF MURINE SIDEROCALIN (LIPOCALIN 2, 24P3)
Descriptor:Neutrophil gelatinase-associated lipocalin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Correnti, C., Bandaranayake, A.D., Strong, R.K.
Deposit date:2011-05-16
Release date:2011-09-28
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Daedalus: a robust, turnkey platform for rapid production of decigram quantities of active recombinant proteins in human cell lines using novel lentiviral vectors.
Nucleic Acids Res., 39, 2011