7SGQ

Protease inhibitors variant, CTI-homolog pacifastin

Summary for 7SGQ

Entry DOI	10.2210/pdb7sgq/pdb
Descriptor	Protease inhibitor LCMI-II, SULFATE ION (3 entities in total)
Functional Keywords	cti, pacifastin, protease inhibitors, toxin
Biological source	Locusta migratoria (Migratory locust)
Total number of polymer chains	6
Total formula weight	22987.74
Authors	Gewe, M.M.,Strong, R.K. (deposition date: 2021-10-07, release date: 2022-08-03, Last modification date: 2023-10-18)
Primary citation	Crook, Z.R.,Girard, E.J.,Sevilla, G.P.,Brusniak, M.Y.,Rupert, P.B.,Friend, D.J.,Gewe, M.M.,Clarke, M.,Lin, I.,Ruff, R.,Pakiam, F.,Phi, T.D.,Bandaranayake, A.,Correnti, C.E.,Mhyre, A.J.,Nairn, N.W.,Strong, R.K.,Olson, J.M. Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager. Sci Transl Med, 14:eabn0402-eabn0402, 2022 Cited by PubMed: 35584229 DOI: 10.1126/scitranslmed.abn0402 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.09 Å)

Structure validation