6OKD

Crystal Structure of human transferrin receptor in complex with a cystine-dense peptide

Summary for 6OKD

Entry DOI	10.2210/pdb6okd/pdb
Descriptor	Transferrin receptor protein 1, transferrin receptor binding cystine-dense peptide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (6 entities in total)
Functional Keywords	protein-protein complex, cystine-dense peptide, transport protein-signaling protein complex, transport protein/signaling protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	164220.86
Authors	Finton, K.A.K.,Rupert, P.B.,Strong, R.K. (deposition date: 2019-04-12, release date: 2020-04-15, Last modification date: 2023-10-11)
Primary citation	Crook, Z.R.,Girard, E.,Sevilla, G.P.,Merrill, M.,Friend, D.,Rupert, P.B.,Pakiam, F.,Nguyen, E.,Yin, C.,Ruff, R.O.,Hopping, G.,Strand, A.D.,Finton, K.A.K.,Coxon, M.,Mhyre, A.J.,Strong, R.K.,Olson, J.M. A TfR-Binding Cystine-Dense Peptide Promotes Blood-Brain Barrier Penetration of Bioactive Molecules. J.Mol.Biol., 432:3989-4009, 2020 Cited by PubMed: 32304700 DOI: 10.1016/j.jmb.2020.04.002 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation