6OKD

Crystal Structure of human transferrin receptor in complex with a cystine-dense peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Transferrin receptor protein 1	polymer	670	75052.7	2	UniProt (P02786) Pfam (PF02225) Pfam (PF04389) Pfam (PF04253) In PDB	Homo sapiens (Human)	Trfr,T9,p90
2	C, D	transferrin receptor binding cystine-dense peptide	polymer	51	5959.6	2		Monosiga brevicollis
3	A, B	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	2	Chemie (MES)
4	A, B	GLYCEROL	non-polymer		92.1	10	Chemie (GOL)
5	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
6		water	water		18.0	782	Chemie (HOH)

Sequence modifications

A, B: 3 - 642 (UniProt: P02786)

PDB	External Database	Details
Gly 1	-	expression tag
Ser 2	-	expression tag
Ser 24	Gly 142	conflict
Gly 643	-	expression tag
Gly 644	-	expression tag
Gly 645	-	expression tag
Ser 646	-	expression tag
His 647	-	expression tag
His 648	-	expression tag
His 649	-	expression tag
His 650	-	expression tag
His 651	-	expression tag
His 652	-	expression tag
Gly 653	-	expression tag
Gly 654	-	expression tag
Gly 655	-	expression tag
Ser 656	-	expression tag
Leu 657	-	expression tag
Asn 658	-	expression tag
Asp 659	-	expression tag
Ile 660	-	expression tag
Phe 661	-	expression tag
Glu 662	-	expression tag
Ala 663	-	expression tag
Gln 664	-	expression tag
Lys 665	-	expression tag
Ile 666	-	expression tag
Glu 667	-	expression tag
Trp 668	-	expression tag
His 669	-	expression tag
Glu 670	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	162024.6
Non-Polymers*	Number of molecules	16
	Total formula weight	2196.2
All*	Total formula weight	164220.9

*Water molecules are not included.