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7SLT

Protease inhibitors variant, CTI-homolog pacifastin

Summary for 7SLT
Entry DOI10.2210/pdb7slt/pdb
DescriptorProtease inhibitor LCMI-II, GLYCEROL (3 entities in total)
Functional Keywordscdp, pacifastin, cti, toxin
Biological sourceLocusta migratoria (Migratory locust)
Total number of polymer chains4
Total formula weight14956.64
Authors
Gewe, M.M.,Strong, R.K. (deposition date: 2021-10-24, release date: 2022-08-03, Last modification date: 2023-10-18)
Primary citationCrook, Z.R.,Girard, E.J.,Sevilla, G.P.,Brusniak, M.Y.,Rupert, P.B.,Friend, D.J.,Gewe, M.M.,Clarke, M.,Lin, I.,Ruff, R.,Pakiam, F.,Phi, T.D.,Bandaranayake, A.,Correnti, C.E.,Mhyre, A.J.,Nairn, N.W.,Strong, R.K.,Olson, J.M.
Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager.
Sci Transl Med, 14:eabn0402-eabn0402, 2022
Cited by
PubMed: 35584229
DOI: 10.1126/scitranslmed.abn0402
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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