3RU8

Structure of an HIV epitope scaffold in complex with neutralizing antibody b12 Fab

Summary for 3RU8

Entry DOI	10.2210/pdb3ru8/pdb
Descriptor	Epitope Scaffold 2bodx43, Antibody b12, Heavy Chain, Antibody b12, Light Chain, ... (5 entities in total)
Functional Keywords	binding epitope from hiv on a heterologous protein, immune system, de novo protein
Biological source	Human immunodeficiency virus, synthetic construct, Thermomonospora fusca More
Total number of polymer chains	3
Total formula weight	79057.90
Authors	Carrico, C.T.D.,Strong, R.K. (deposition date: 2011-05-04, release date: 2011-11-02, Last modification date: 2023-09-13)
Primary citation	Azoitei, M.L.,Correia, B.E.,Ban, Y.E.,Carrico, C.,Kalyuzhniy, O.,Chen, L.,Schroeter, A.,Huang, P.S.,McLellan, J.S.,Kwong, P.D.,Baker, D.,Strong, R.K.,Schief, W.R. Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold. Science, 334:373-376, 2011 Cited by PubMed: 22021856 DOI: 10.1126/science.1209368 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.07 Å)

Structure validation