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1T7D
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI TYPE I SIGNAL PEPTIDASE IN COMPLEX WITH A LIPOPEPTIDE INHIBITOR
Descriptor:SIGNAL PEPTIDASE I, ARYLOMYCIN A2, 10-METHYLUNDECANOIC ACID
Authors:Paetzel, M., Goodall, J.J., Kania, M., Dalbey, R.E., Page, M.G.P.
Deposit date:2004-05-09
Release date:2004-07-13
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Crystallographic and Biophysical Analysis of a Bacterial Signal Peptidase in Complex with a Lipopeptide Based Inhibitor.
J.Biol.Chem., 279, 2004
1KN9
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CRYSTAL STRUCTURE OF A BACTERIAL SIGNAL PEPTIDASE APO-ENZYME, IMPLICATIONS FOR SIGNAL PEPTIDE BINDING AND THE SER-LYS DYAD MECHANISM.
Descriptor:Signal peptidase I
Authors:Paetzel, M., Dalbey, R.E., Strynadka, N.C.J.
Deposit date:2001-12-18
Release date:2002-01-30
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of a bacterial signal peptidase apoenzyme: implications for signal peptide binding and the Ser-Lys dyad mechanism
J.Biol.Chem., 277, 2002
1B12
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CRYSTAL STRUCTURE OF TYPE 1 SIGNAL PEPTIDASE FROM ESCHERICHIA COLI IN COMPLEX WITH A BETA-LACTAM INHIBITOR
Descriptor:SIGNAL PEPTIDASE I, prop-2-en-1-yl (2S)-2-[(2S,3R)-3-(acetyloxy)-1-oxobutan-2-yl]-2,3-dihydro-1,3-thiazole-4-carboxylate, PHOSPHATE ION
Authors:Paetzel, M., Dalbey, R., Strynadka, N.C.J.
Deposit date:1999-11-24
Release date:1999-12-10
Last modified:2012-05-09
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of a bacterial signal peptidase in complex with a beta-lactam inhibitor.
Nature, 396, 1998
1FOF
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CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-10
Descriptor:BETA LACTAMASE OXA-10, COBALT (II) ION, SULFATE ION
Authors:Paetzel, M., Danel, F., de Castro, L., Mosimann, S.C., Page, M.G.P., Strynadka, N.C.J.
Deposit date:2000-08-28
Release date:2000-10-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the class D beta-lactamase OXA-10.
Nat.Struct.Biol., 7, 2000
2PNL
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CRYSTAL STRUCTURE OF VP4 PROTEASE FROM INFECTIOUS PANCREATIC NECROSIS VIRUS (IPNV) IN SPACE GROUP P1
Descriptor:Protease VP4, GUANIDINE
Authors:Paetzel, M., Lee, J., Feldman, A.R., Delmas, B.
Deposit date:2007-04-24
Release date:2007-06-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal structure of the VP4 protease from infectious pancreatic necrosis virus reveals the acyl-enzyme complex for an intermolecular self-cleavage reaction.
J.Biol.Chem., 282, 2007
2PNM
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CRYSTAL STRUCTURE OF VP4 PROTEASE FROM INFECTIOUS PANCREATIC NECROSIS VIRUS (IPNV) IN SPACE GROUP P6122
Descriptor:Protease VP4
Authors:Paetzel, M., Lee, J., Feldman, A.R., Delmas, B.
Deposit date:2007-04-24
Release date:2007-06-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the VP4 protease from infectious pancreatic necrosis virus reveals the acyl-enzyme complex for an intermolecular self-cleavage reaction.
J.Biol.Chem., 282, 2007
2GEF
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CRYSTAL STRUCTURE OF A NOVEL VIRAL PROTEASE WITH A SERINE/LYSINE CATALYTIC DYAD MECHANISM
Descriptor:Protease VP4
Authors:Paetzel, M., Feldman, A.R., Lee, J., Delmas, B.
Deposit date:2006-03-20
Release date:2006-05-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a novel viral protease with a serine/lysine catalytic dyad mechanism
J.Mol.Biol., 358, 2006
3BEZ
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI SIGNAL PEPTIDE PEPTIDASE (SPPA), SEMET CRYSTALS
Descriptor:Protease 4
Authors:Paetzel, M.
Deposit date:2007-11-20
Release date:2007-12-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Crystal structure of a bacterial signal Peptide peptidase.
J.Mol.Biol., 376, 2008
3BF0
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI SIGNAL PEPTIDE PEPTIDASE (SPPA), NATIVE CRYSTALS
Descriptor:Protease 4
Authors:Paetzel, M.
Deposit date:2007-11-20
Release date:2007-12-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structure of a bacterial signal Peptide peptidase.
J.Mol.Biol., 376, 2008
3BLC
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CRYSTAL STRUCTURE OF THE PERIPLASMIC DOMAIN OF THE ESCHERICHIA COLI YIDC
Descriptor:Inner membrane protein oxaA
Authors:Paetzel, M., Oliver, D.C.
Deposit date:2007-12-10
Release date:2007-12-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the Major Periplasmic Domain of the Bacterial Membrane Protein Assembly Facilitator YidC.
J.Biol.Chem., 283, 2008
3IIQ
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CRYSTALLOGRAPHIC ANALYSIS OF BACTERIAL SIGNAL PEPTIDASE IN TERNARY COMPLEX WITH ARYLOMYCIN A2 AND A BETA-SULTAM INHIBITOR
Descriptor:SIGNAL PEPTIDASE I, ARYLOMYCIN A2, 4-[(1,1-dioxido-1,2-thiazetidin-2-yl)carbonyl]morpholine, ...
Authors:Paetzel, M.
Deposit date:2009-08-03
Release date:2009-09-01
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic Analysis of Bacterial Signal Peptidase in Ternary Complex with Arylomycin A2 and a Beta-Sultam Inhibitor.
Biochemistry, 48, 2009
3S04
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI TYPE I SIGNAL PEPTIDASE IN COMPLEX WITH AN ARYLOMYCIN LIPOGLYCOPEPTIDE ANTIBIOTIC
Descriptor:Signal peptidase I, Glyco-Arylomycin, 14-methylhexadec-9-enoic acid, ...
Authors:Paetzel, M., Luo, C.
Deposit date:2011-05-13
Release date:2011-10-05
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Synthesis and characterization of the arylomycin lipoglycopeptide antibiotics and the crystallographic analysis of their complex with signal peptidase.
J.Am.Chem.Soc., 133, 2011
3TGO
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CRYSTAL STRUCTURE OF THE E. COLI BAMCD COMPLEX
Descriptor:UPF0169 lipoprotein yfiO, Lipoprotein 34, POTASSIUM ION, ...
Authors:Paetzel, M., Kim, K.H., Aulakh, S.
Deposit date:2011-08-17
Release date:2011-09-28
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the beta-barrel assembly machinery BamCD protein complex
J.Biol.Chem., 286, 2011
4IZJ
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CRYSTAL STRUCTURE OF YELLOWTAIL ASCITES VIRUS VP4 PROTEASE WITH A WILD-TYPE ACTIVE SITE REVEALS ACYL-ENZYME COMPLEXES AND PRODUCT COMPLEXES.
Descriptor:Yellowtail Ascites Virus (YAV) VP4 protease, BETA-MERCAPTOETHANOL, MAGNESIUM ION, ...
Authors:Paetzel, M., Chung, I.Y.W.
Deposit date:2013-01-30
Release date:2013-02-27
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures of Yellowtail Ascites Virus VP4 Protease: TRAPPING AN INTERNAL CLEAVAGE SITE TRANS ACYL-ENZYME COMPLEX IN A NATIVE SER/LYS DYAD ACTIVE SITE.
J.Biol.Chem., 288, 2013
4IZK
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CRYSTAL STRUCTURE OF YELLOWTAIL ASCITES VIRUS VP4 PROTEASE ACTIVE SITE MUTANT (K674A) REVEALS BOTH AN ACYL-ENZYME COMPLEX AND AN EMPTY ACTIVE SITE
Descriptor:Yellowtail Ascites Virus (YAV) VP4 protease, MAGNESIUM ION, BETA-MERCAPTOETHANOL
Authors:Paetzel, M., Chung, I.Y.W.
Deposit date:2013-01-30
Release date:2013-02-27
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures of Yellowtail Ascites Virus VP4 Protease: TRAPPING AN INTERNAL CLEAVAGE SITE TRANS ACYL-ENZYME COMPLEX IN A NATIVE SER/LYS DYAD ACTIVE SITE.
J.Biol.Chem., 288, 2013
3P06
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CRYSTAL STRUCTURE OF TELLINA VIRUS 1 VP4 PROTEASE IN THE FORM OF AN INTRA-MOLECULAR(CIS)ACYL-ENZYME COMPLEX.
Descriptor:VP4 protein, SULFATE ION, GLYCEROL, ...
Authors:Chung, I.Y.W., Paetzel, M.
Deposit date:2010-09-27
Release date:2011-02-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of a Viral Protease Intramolecular Acyl-enzyme Complex: INSIGHTS INTO cis-CLEAVAGE AT THE VP4/VP3 JUNCTION OF TELLINA BIRNAVIRUS.
J.Biol.Chem., 286, 2011
1ERM
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X-RAY CRYSTAL STRUCTURE OF TEM-1 BETA LACTAMASE IN COMPLEX WITH A DESIGNED BORONIC ACID INHIBITOR (1R)-1-ACETAMIDO-2-(3-CARBOXYPHENYL)ETHANE BORONIC ACID
Descriptor:TEM-1 BETA-LACTAMASE, 1(R)-1-ACETAMIDO-2-(3-CARBOXYPHENYL)ETHYL BORONIC ACID
Authors:Ness, S., Martin, R., Kindler, A.M., Paetzel, M., Gold, M., Jones, J.B., Strynadka, N.C.J.
Deposit date:2000-04-06
Release date:2000-05-10
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure-based design guides the improved efficacy of deacylation transition state analogue inhibitors of TEM-1 beta-Lactamase(,).
Biochemistry, 39, 2000
1ERO
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X-RAY CRYSTAL STRUCTURE OF TEM-1 BETA LACTAMASE IN COMPLEX WITH A DESIGNED BORONIC ACID INHIBITOR (1R)-2-PHENYLACETAMIDO-2-(3-CARBOXYPHENYL)ETHYL BORONIC ACID
Descriptor:TEM-1 BETA-LACTAMASE, (1R)-2-PHENYLACETAMIDO-2-(3-CARBOXYPHENYL)ETHYL BORONIC ACID
Authors:Ness, S., Martin, R., Kindler, A.M., Paetzel, M., Gold, M., Jones, J.B., Strynadka, N.C.J.
Deposit date:2000-04-06
Release date:2000-05-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-based design guides the improved efficacy of deacylation transition state analogue inhibitors of TEM-1 beta-Lactamase(,).
Biochemistry, 39, 2000
1ERQ
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X-RAY CRYSTAL STRUCTURE OF TEM-1 BETA LACTAMASE IN COMPLEX WITH A DESIGNED BORONIC ACID INHIBITOR (1R)-1-ACETAMIDO-2-(3-CARBOXY-2-HYDROXYPHENYL)ETHYL BORONIC ACID
Descriptor:TEM-1 BETA-LACTAMASE, 1(R)-1-ACETAMIDO-2-(3-CARBOXY-2-HYDROXYPHENYL)ETHYL BORONIC ACID
Authors:Ness, S., Martin, R., Kindler, A.M., Paetzel, M., Gold, M., Jones, J.B., Strynadka, N.C.J.
Deposit date:2000-04-06
Release date:2000-05-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-based design guides the improved efficacy of deacylation transition state analogue inhibitors of TEM-1 beta-Lactamase(,).
Biochemistry, 39, 2000
2KXX
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NMR STRUCTURE OF ESCHERICHIA COLI BAME, A LIPOPROTEIN COMPONENT OF THE BETA-BARREL ASSEMBLY MACHINERY COMPLEX
Descriptor:Small protein A
Authors:Kim, K., Okon, M., Escobar, E., Kang, H., McIntosh, L., Paetzel, M.
Deposit date:2010-05-13
Release date:2011-01-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural Characterization of Escherichia coli BamE, a Lipoprotein Component of the beta-Barrel Assembly Machinery Complex.
Biochemistry, 50, 2011
2Q2H
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CRYSTAL STRUCTURE OF THE PROTEIN SECRETION CHAPERONE CSAA FROM AGROBACTERIUM TUMEFACIENS WITH A GENETICALLY FUSED PHAGE-DISPLAY DERIVED PEPTIDE SUBSTRATE AT THE N-TERMINUS.
Descriptor:Secretion chaperone, phage-display derived peptide, CITRIC ACID, ...
Authors:Feldman, A.R., Shapova, Y.A., Paetzel, M.
Deposit date:2007-05-28
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Phage display and crystallographic analysis reveals potential substrate/binding site interactions in the protein secretion chaperone CsaA from Agrobacterium tumefaciens.
J.Mol.Biol., 379, 2008
2Q2I
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CRYSTAL STRUCTURE OF THE PROTEIN SECRETION CHAPERONE CSAA FROM AGROBACTERIUM TUMEFACIENS.
Descriptor:Secretion chaperone, SULFATE ION, 1,2-ETHANEDIOL
Authors:Feldman, A.R., Shapova, Y.A., Paetzel, M.
Deposit date:2007-05-28
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Phage display and crystallographic analysis reveals potential substrate/binding site interactions in the protein secretion chaperone CsaA from Agrobacterium tumefaciens.
J.Mol.Biol., 379, 2008
2MQ0
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NMR STRUCTURE OF THE C3 DOMAIN OF HUMAN CARDIAC MYOSIN BINDING PROTEIN-C
Descriptor:Myosin-binding protein C, cardiac-type
Authors:Zhang, X., De, S., Mcintosh, L.P., Paetzel, M.
Deposit date:2014-06-10
Release date:2014-07-30
Last modified:2014-08-27
Method:SOLUTION NMR
Cite:Structural Characterization of the C3 Domain of Cardiac Myosin Binding Protein C and Its Hypertrophic Cardiomyopathy-Related R502W Mutant.
Biochemistry, 53, 2014
2MQ3
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NMR STRUCTURE OF THE C3 DOMAIN OF HUMAN CARDIAC MYOSIN BINDING PROTEIN-C WITH A HYPERTROPHIC CARDIOMYOPATHY-RELATED MUTATION R502W.
Descriptor:Myosin-binding protein C, cardiac-type
Authors:Zhang, X., De, S., Mcintosh, L.P., Paetzel, M.
Deposit date:2014-06-12
Release date:2014-07-30
Last modified:2014-08-27
Method:SOLUTION NMR
Cite:Structural Characterization of the C3 Domain of Cardiac Myosin Binding Protein C and Its Hypertrophic Cardiomyopathy-Related R502W Mutant.
Biochemistry, 53, 2014
2NZH
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CRYSTAL STRUCTURE OF A SECRETION CHAPERONE CSAA FROM BACILLUS SUBTILIS IN THE SPACE GROUP P 4 21 2
Descriptor:Protein csaA, GLYCEROL
Authors:Shapova, Y.A., Paetzel, M.
Deposit date:2006-11-23
Release date:2007-03-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystallographic analysis of Bacillus subtilis CsaA.
Acta Crystallogr.,Sect.D, 63, 2007
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