4IZJ
Crystal structure of yellowtail ascites virus VP4 protease with a wild-type active site reveals acyl-enzyme complexes and product complexes.
Replaces: 3R0BSummary for 4IZJ
| Entry DOI | 10.2210/pdb4izj/pdb |
| Related | 2GEF 2PNL 2PNM 3P06 4IZK |
| Descriptor | Yellowtail Ascites Virus (YAV) VP4 protease, BETA-MERCAPTOETHANOL, MAGNESIUM ION, ... (7 entities in total) |
| Functional Keywords | viral protease, birnavirus, serine-lysine dyad mechanism, alpha-beta protein fold, lysine general base, acyl-enzyme, product complex, hydrolase |
| Biological source | Yellowtail ascites virus More |
| Total number of polymer chains | 5 |
| Total formula weight | 112259.29 |
| Authors | Paetzel, M.,Chung, I.Y.W. (deposition date: 2013-01-30, release date: 2013-02-27, Last modification date: 2023-12-06) |
| Primary citation | Chung, I.Y.,Paetzel, M. Crystal Structures of Yellowtail Ascites Virus VP4 Protease: TRAPPING AN INTERNAL CLEAVAGE SITE TRANS ACYL-ENZYME COMPLEX IN A NATIVE SER/LYS DYAD ACTIVE SITE. J.Biol.Chem., 288:13068-13081, 2013 Cited by PubMed: 23511637DOI: 10.1074/jbc.M112.386953 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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