1B12

CRYSTAL STRUCTURE OF TYPE 1 SIGNAL PEPTIDASE FROM ESCHERICHIA COLI IN COMPLEX WITH A BETA-LACTAM INHIBITOR

Summary for 1B12

Entry DOI	10.2210/pdb1b12/pdb
Descriptor	SIGNAL PEPTIDASE I, prop-2-en-1-yl (2S)-2-[(2S,3R)-3-(acetyloxy)-1-oxobutan-2-yl]-2,3-dihydro-1,3-thiazole-4-carboxylate, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	serine proteinase, serine-dependant hydrolase, signal peptide processing, protein translocation, membrane bound proteinase, membrane protein, hydrolase
Biological source	Escherichia coli
Cellular location	Cell inner membrane; Multi-pass membrane protein: P00803
Total number of polymer chains	4
Total formula weight	112634.20
Authors	Paetzel, M.,Dalbey, R.,Strynadka, N.C.J. (deposition date: 1999-11-24, release date: 1999-12-10, Last modification date: 2023-12-27)
Primary citation	Paetzel, M.,Dalbey, R.E.,Strynadka, N.C. Crystal structure of a bacterial signal peptidase in complex with a beta-lactam inhibitor. Nature, 396:186-190, 1998 Cited by PubMed: 9823901 DOI: 10.1038/24196 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation