1T7D

Crystal structure of Escherichia coli type I signal peptidase in complex with a lipopeptide inhibitor

Summary for 1T7D

Related1B12 1KN9 3IIQ
Related PRD IDPRD_000117
DescriptorSIGNAL PEPTIDASE I, ARYLOMYCIN A2, 10-METHYLUNDECANOIC ACID, ... (4 entities in total)
Functional Keywordssignal peptidase, ser/lys dyad, hydrolase, lipopeptide, antibiotic, biaryl bridge, hydrolase-antibiotic complex, hydrolase/antibiotic
Biological sourceESCHERICHIA COLI
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Cellular locationCell inner membrane; Multi-pass membrane protein P00803
Total number of polymer chains4
Total molecular weight57849.61
Authors
Paetzel, M.,Goodall, J.J.,Kania, M.,Dalbey, R.E.,Page, M.G.P. (deposition date: 2004-05-09, release date: 2004-07-13, Last modification date: 2012-12-12)
Primary citation
Paetzel, M.,Goodall, J.J.,Kania, M.,Dalbey, R.E.,Page, M.G.P.
Crystallographic and Biophysical Analysis of a Bacterial Signal Peptidase in Complex with a Lipopeptide Based Inhibitor.
J.Biol.Chem., 279:30781-, 2004
PubMed: 15136583 (PDB entries with the same primary citation)
DOI: 10.1074/JBC.M401686200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.47 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.281171.4%5.6%6.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1t7d
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Molmil generated image of 1t7d
rotated about x axis by 90°
Molmil generated image of 1t7d
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 1t7d
no rotation
Molmil generated image of 1t7d
rotated about x axis by 90°
Molmil generated image of 1t7d
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (1t7d.pdb2.gz [39.85 KB])
Coordinate files for Biological unit (1t7d.pdb1.gz [42.09 KB])