1T7D
Crystal structure of Escherichia coli type I signal peptidase in complex with a lipopeptide inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | SIGNAL PEPTIDASE I | polymer | 250 | 28079.8 | 2 | UniProt (P00803) Pfam (PF10502) In PDB | ESCHERICHIA COLI | SPASE I, LEADER PEPTIDASE I |
| 2 | C, D | ARYLOMYCIN A2 | polymer | 6 | 644.7 | 2 | NOR (NOR01115) BIRD (PRD_000117) | STREPTOMYCES TU | |
| 3 | C, D | 10-METHYLUNDECANOIC ACID | non-polymer | 200.3 | 2 | BIRD (PRD_000117) Chemie (M12) | |||
| 4 | water | water | 18.0 | 265 | Chemie (HOH) |
Sequence modifications
A, B: 75 - 323 (UniProt: P00803)
C, D: 1 - 6 (NOR: NOR01115)
| PDB | External Database | Details |
|---|---|---|
| Met 74 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 57449.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 400.6 | |
| All* | Total formula weight | 57849.6 |
