2PNL

Crystal structure of VP4 protease from infectious pancreatic necrosis virus (IPNV) in space group P1

Summary for 2PNL

• Entry DOI: 10.2210/pdb2pnl/pdb
• Related: 2GEF 2PNM
• Descriptor: Protease VP4, GUANIDINE (3 entities in total)
• Functional Keywords: acyl-enzyme, protease, ser/lys dyad, viral protease, substrate complex, product complex, hydrolase
• Biological source: Infectious pancreatic necrosis virus
• Cellular location: Capsid protein VP2: Virion (Potential). Capsid protein VP3: Virion (Potential). Structural peptide 1: Virion (Potential). Structural peptide 2: Virion (Potential). Structural peptide 3: Virion (Potential): Q703G9
• Total number of polymer chains: 10
• Total formula weight: 218566.01

Authors

Paetzel, M.,Lee, J.,Feldman, A.R.,Delmas, B. (deposition date: 2007-04-24, release date: 2007-06-05, Last modification date: 2021-10-20)

• Primary citation: Lee, J.,Feldman, A.R.,Delmas, B.,Paetzel, M.; Crystal structure of the VP4 protease from infectious pancreatic necrosis virus reveals the acyl-enzyme complex for an intermolecular self-cleavage reaction.; J.Biol.Chem., 282:24928-24937, 2007; PubMed: 17553791; DOI: 10.1074/jbc.M701551200

Experimental method

X-RAY DIFFRACTION (2.21 Å)