2PNL
Crystal structure of VP4 protease from infectious pancreatic necrosis virus (IPNV) in space group P1
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GAI A 2002 |
| Chain | Residue |
| A | LEU524 |
| A | ASN528 |
| A | HIS547 |
| A | HOH2006 |
| A | HOH2037 |
| A | HOH2039 |
| E | HOH2033 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GAI A 2005 |
| Chain | Residue |
| A | SER700 |
| A | ALA703 |
| A | ASP644 |
| A | THR699 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GAI B 2003 |
| Chain | Residue |
| B | PRO536 |
| B | ASN616 |
| B | ASN618 |
| H | HIS581 |
| H | HOH2155 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GAI B 2004 |
| Chain | Residue |
| B | SER559 |
| B | LEU610 |
| B | GLU622 |
| B | HOH2015 |
| B | HOH2040 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GAI B 2009 |
| Chain | Residue |
| B | LEU524 |
| B | ASN528 |
| B | HIS547 |
| B | PHE625 |
| B | HOH2032 |
| B | HOH2036 |
| B | HOH2040 |
| B | HOH2062 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GAI C 2001 |
| Chain | Residue |
| C | SER559 |
| C | LEU610 |
| C | GLU622 |
| C | HOH2045 |
| C | HOH2099 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GAI C 2006 |
| Chain | Residue |
| C | LEU524 |
| C | ASN528 |
| C | HIS547 |
| C | HOH2019 |
| C | HOH2099 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GAI C 2014 |
| Chain | Residue |
| C | HIS581 |
| H | PRO536 |
| H | ASN616 |
| H | ASN618 |
| H | HOH2075 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GAI D 2010 |
| Chain | Residue |
| C | HOH2124 |
| D | LEU524 |
| D | ASN528 |
| D | HIS547 |
| D | ILE624 |
| D | HOH2016 |
| D | HOH2035 |
| D | HOH2051 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GAI E 2007 |
| Chain | Residue |
| E | LEU524 |
| E | ASN528 |
| E | HIS547 |
| E | PHE557 |
| E | HOH2016 |
| E | HOH2018 |
| E | HOH2044 |
| E | HOH2104 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GAI E 2015 |
| Chain | Residue |
| E | HIS581 |
| J | PRO536 |
| J | ASN616 |
| J | ASN618 |
| J | HOH2026 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GAI F 2011 |
| Chain | Residue |
| F | LEU524 |
| F | ASN528 |
| F | HIS547 |
| F | PHE557 |
| F | PHE625 |
| F | HOH2062 |
| site_id | BC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GAI H 2008 |
| Chain | Residue |
| H | LEU524 |
| H | ASN528 |
| H | HIS547 |
| H | PHE557 |
| H | HOH2048 |
| H | HOH2049 |
| H | HOH2068 |
| H | HOH2154 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GAI H 2016 |
| Chain | Residue |
| H | PRO597 |
| H | PHE598 |
| H | ALA659 |
| H | ASP660 |
| H | HOH2134 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GAI H 2017 |
| Chain | Residue |
| H | ARG715 |
| H | ALA716 |
| I | VAL546 |
| I | CYS669 |
| site_id | BC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GAI I 2012 |
| Chain | Residue |
| I | LEU524 |
| I | ASN528 |
| I | HIS547 |
| I | PHE557 |
| I | PHE625 |
| I | HOH2022 |
| I | HOH2027 |
| I | HOH2028 |
| I | HOH2080 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GAI J 2013 |
| Chain | Residue |
| J | HIS547 |
| J | HOH2060 |
| J | HOH2064 |
| J | LEU524 |
| J | ASN528 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PROSITE-ProRule","id":"PRU00881","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"10666235","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00881","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"10666235","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
