7JOY
Product structure of SARS-CoV-2 Mpro C145A mutant in complex with its C-terminal autoprocessing sequence.
Summary for 7JOY
| Entry DOI | 10.2210/pdb7joy/pdb |
| Related | 7JOX |
| Descriptor | 3C-like proteinase (2 entities in total) |
| Functional Keywords | protease, sars-cov-2, viral protein |
| Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) |
| Total number of polymer chains | 2 |
| Total formula weight | 67586.96 |
| Authors | Lee, J.,Worrall, L.J.,Paetzel, M.,Strynadka, N.C.J. (deposition date: 2020-08-07, release date: 2020-10-07, Last modification date: 2023-10-18) |
| Primary citation | Lee, J.,Worrall, L.J.,Vuckovic, M.,Rosell, F.I.,Gentile, F.,Ton, A.T.,Caveney, N.A.,Ban, F.,Cherkasov, A.,Paetzel, M.,Strynadka, N.C.J. Crystallographic structure of wild-type SARS-CoV-2 main protease acyl-enzyme intermediate with physiological C-terminal autoprocessing site. Nat Commun, 11:5877-5877, 2020 Cited by PubMed: 33208735DOI: 10.1038/s41467-020-19662-4 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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