Author results

1QUU
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CRYSTAL STRUCTURE OF TWO CENTRAL SPECTRIN-LIKE REPEATS FROM ALPHA-ACTININ
Descriptor:HUMAN SKELETAL MUSCLE ALPHA-ACTININ 2
Authors:Djinovic-Carugo, K., Young, P., Gautel, M., Saraste, M.
Deposit date:1999-07-03
Release date:1999-08-20
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the alpha-actinin rod: molecular basis for cross-linking of actin filaments.
Cell(Cambridge,Mass.), 98, 1999
1PZS
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CRYSTAL STRUCTURE OF A CU-ZN SUPEROXIDE DISMUTASE FROM MYCOBACTERIUM TUBERCULOSIS AT 1.63 RESOLUTION
Descriptor:Superoxide dismutase [Cu-Zn], COPPER (II) ION
Authors:Djinovic-Carugo, K., Spagnolo, L., Toro, I.
Deposit date:2003-07-14
Release date:2004-07-27
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Unique Features of the sodC-encoded Superoxide Dismutase from Mycobacterium tuberculosis, a Fully Functional Copper-containing Enzyme Lacking Zinc in the Active Site.
J.Biol.Chem., 279, 2004
1FWX
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CRYSTAL STRUCTURE OF NITROUS OXIDE REDUCTASE FROM P. DENITRIFICANS
Descriptor:NITROUS OXIDE REDUCTASE, CHLORIDE ION, CALCIUM ION, ...
Authors:Brown, K., Djinovic-Carugo, K., Haltia, T., Cabrito, I., Saraste, M., Moura, J.J., Moura, I., Tegoni, M., Cambillau, C.
Deposit date:2000-09-25
Release date:2001-09-25
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Revisiting the Catalytic CuZ Cluster of Nitrous Oxide (N2O) Reductase. Evidence of a Bridging Inorganic Sulfur
J.Biol.Chem., 275, 2000
4M05
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CRYSTAL STRUCTURE OF MUTANT CHLORITE DISMUTASE FROM CANDIDATUS NITROSPIRA DEFLUVII R173E
Descriptor:Chlorite dismutase, PROTOPORPHYRIN IX CONTAINING FE, ACETATE ION, ...
Authors:Gysel, K., Hagmueller, A., Djinovic-Carugo, K.
Deposit date:2013-08-01
Release date:2014-01-15
Last modified:2014-01-29
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Manipulating conserved heme cavity residues of chlorite dismutase: effect on structure, redox chemistry, and reactivity.
Biochemistry, 53, 2014
4M06
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CRYSTAL STRUCTURE OF MUTANT CHLORITE DISMUTASE FROM CANDIDATUS NITROSPIRA DEFLUVII W145F IN COMPLEX WITH CYANIDE
Descriptor:Chlorite dismutase, PROTOPORPHYRIN IX CONTAINING FE, GLYCEROL, ...
Authors:Hagmueller, A., Gysel, K., Djinovic-Carugo, K.
Deposit date:2013-08-01
Release date:2014-01-15
Last modified:2014-01-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Manipulating conserved heme cavity residues of chlorite dismutase: effect on structure, redox chemistry, and reactivity.
Biochemistry, 53, 2014
4M07
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CRYSTAL STRUCTURE OF MUTANT CHLORITE DISMUTASE FROM CANDIDATUS NITROSPIRA DEFLUVII W145F
Descriptor:Chlorite dismutase, PROTOPORPHYRIN IX CONTAINING FE, 1,2-ETHANEDIOL, ...
Authors:Hagmueller, A., Gysel, K., Djinovic-Carugo, K.
Deposit date:2013-08-01
Release date:2014-01-15
Last modified:2014-01-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Manipulating conserved heme cavity residues of chlorite dismutase: effect on structure, redox chemistry, and reactivity.
Biochemistry, 53, 2014
4M08
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CRYSTAL STRUCTURE OF MUTANT CHLORITE DISMUTASE FROM CANDIDATUS NITROSPIRA DEFLUVII W145V
Descriptor:Chlorite dismutase, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ...
Authors:Gysel, K., Hagmueller, A., Djinovic-Carugo, K.
Deposit date:2013-08-01
Release date:2014-01-15
Last modified:2014-01-29
Method:X-RAY DIFFRACTION (2.799 Å)
Cite:Manipulating conserved heme cavity residues of chlorite dismutase: effect on structure, redox chemistry, and reactivity.
Biochemistry, 53, 2014
4M09
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CRYSTAL STRUCTURE OF MUTANT CHLORITE DISMUTASE FROM CANDIDATUS NITROSPIRA DEFLUVII W146Y R173Q
Descriptor:Chlorite dismutase, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ...
Authors:Gysel, K., Hagmueller, A., Djinovic-Carugo, K.
Deposit date:2013-08-01
Release date:2014-01-15
Last modified:2014-01-29
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Manipulating conserved heme cavity residues of chlorite dismutase: effect on structure, redox chemistry, and reactivity.
Biochemistry, 53, 2014
4TOI
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CRYSTAL STRUCTURE OF E.COLI RIBOSOMAL PROTEIN S2 IN COMPLEX WITH N-TERMINAL DOMAIN OF S1
Descriptor:30S ribosomal protein S2,Ribosomal protein S1, ZINC ION
Authors:Grishkovskaya, I., Byrgazov, K., Moll, I., Djinovic-Carugo, K.
Deposit date:2014-06-05
Release date:2014-12-31
Last modified:2015-01-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for the interaction of protein S1 with the Escherichia coli ribosome.
Nucleic Acids Res., 43, 2015
5K33
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CRYSTAL STRUCTURE OF EXTRACELLULAR DOMAIN OF HER2 IN COMPLEX WITH FCAB STAB19
Descriptor:Ig gamma-1 chain C region, Receptor tyrosine-protein kinase erbB-2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Humm, A., Lobner, E., Goritzer, K., Mlynek, G., Obinger, C., Djinovic-Carugo, K.
Deposit date:2016-05-19
Release date:2017-04-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Fcab-HER2 Interaction: a Menage a Trois. Lessons from X-Ray and Solution Studies.
Structure, 25, 2017
5KWG
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CRYSTAL STRUCTURE OF EXTRACELLULAR DOMAIN OF HER2 IN COMPLEX WITH FCAB H10-03-6
Descriptor:Receptor tyrosine-protein kinase erbB-2, Ig gamma-1 chain C region
Authors:Humm, A., Lobner, E., Goritzer, K., Mlynek, G., Obinger, C., Djinovic-Carugo, K.
Deposit date:2016-07-18
Release date:2017-04-12
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Fcab-HER2 Interaction: a Menage a Trois. Lessons from X-Ray and Solution Studies.
Structure, 25, 2017
5MAV
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CRYSTAL STRUCTURE OF HUMAN PCNA IN COMPLEX WITH PARG (POLY(ADP-RIBOSE) GLYCOHYDROLASE) PEPTIDE.
Descriptor:Proliferating cell nuclear antigen, Poly (ADP-ribose) glycohydrolase
Authors:Grishkovskaya, I., Djinovic-Carugo, K., Slade, D.
Deposit date:2016-11-06
Release date:2017-08-02
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.575 Å)
Cite:A novel non-canonical PIP-box mediates PARG interaction with PCNA.
Nucleic Acids Res., 45, 2017
5O4E
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CRYSTAL STRUCTURE OF VEGF IN COMPLEX WITH HETERODIMERIC FCAB JANUSCT6
Descriptor:Immunoglobulin gamma-1 heavy chain, Vascular endothelial growth factor A, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Mlynek, G., Lobner, E., Kubinger, K., Humm, A., Obinger, C., Djinovic-Carugo, K.
Deposit date:2017-05-29
Release date:2017-08-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Two-faced Fcab prevents polymerization with VEGF and reveals thermodynamics and the 2.15 angstrom crystal structure of the complex.
MAbs, 9, 2017
2N8Y
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HOLO FORM OF CALMODULIN-LIKE DOMAIN OF HUMAN NON-MUSCLE ALPHA-ACTININ 1
Descriptor:Alpha-actinin-1, CALCIUM ION
Authors:Drmota Prebil, S., Slapsak, U., de Almeida Ribeiro, E., Pavsic, M., Ilc, G., Zielinska, K., Hartl, M., Backman, L., Plavec, J., Lenarcic, B., Djinovic-Carugo, K.
Deposit date:2015-10-28
Release date:2016-06-29
Method:SOLUTION NMR
Cite:Structure and calcium-binding studies of calmodulin-like domain of human non-muscle alpha-actinin-1.
Sci Rep, 6, 2016
2N8Z
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APO FORM OF CALMODULIN-LIKE DOMAIN OF HUMAN NON-MUSCLE ALPHA-ACTININ 1
Descriptor:Alpha-actinin-1
Authors:Drmota Prebil, S., Slapsak, U., de Almeida Ribeiro, E., Pavsic, M., Ilc, G., Zielinska, K., Hartl, M., Backman, L., Plavec, J., Lenarcic, B., Djinovic-Carugo, K.
Deposit date:2015-10-28
Release date:2016-06-29
Method:SOLUTION NMR
Cite:Structure and calcium-binding studies of calmodulin-like domain of human non-muscle alpha-actinin-1.
Sci Rep, 6, 2016
3QO3
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI HFQ, IN COMPLEX WITH ATP
Descriptor:Protein hfq, ADENOSINE-5'-TRIPHOSPHATE
Authors:Beich-Frandsen, M., Vecerek, B., Hammele, H., Kloiber, K., Sjoeblom, B., Blasi, U., Djinovic-Carugo, K.
Deposit date:2011-02-09
Release date:2012-02-15
Last modified:2013-03-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural and biochemical studies on ATP binding and hydrolysis by the Escherichia coli RNA chaperone Hfq
Plos One, 7, 2012
3QPI
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CRYSTAL STRUCTURE OF DIMERIC CHLORITE DISMUTASES FROM NITROBACTER WINOGRADSKYI
Descriptor:Chlorite Dismutase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Mlynek, G., Sjoeblom, B., Kostan, J., Fuereder, S., Maixner, F., Furtmueller, P.G., Obinger, O., Wagner, M., Daims, H., Djinovic-Carugo, K.
Deposit date:2011-02-13
Release date:2011-07-06
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Unexpected diversity of chlorite dismutases: a catalytically efficient dimeric enzyme from Nitrobacter winogradskyi.
J.Bacteriol., 193, 2011
5JIH
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CRYSTAL STRUCTURE OF HER2 BINDING IGG1-FC (FCAB STAB19)
Descriptor:Ig gamma-1 chain C region, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Humm, A., Lobner, E., Mlynek, G., Obinger, C., Djinovic-Carugo, K.
Deposit date:2016-04-22
Release date:2017-04-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.663 Å)
Cite:Fcab-HER2 Interaction: a Menage a Trois. Lessons from X-Ray and Solution Studies.
Structure, 25, 2017
5JII
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CRYSTAL STRUCTURE OF HUMAN IGG1-FC
Descriptor:Ig gamma-1 chain C region, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Humm, A., Lobner, E., Mlynek, G., Obinger, C., Djinovic-Carugo, K.
Deposit date:2016-04-22
Release date:2017-04-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Fcab-HER2 Interaction: a Menage a Trois. Lessons from X-Ray and Solution Studies.
Structure, 25, 2017
5JIK
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CRYSTAL STRUCTURE OF HER2 BINDING IGG1-FC (FCAB H10-03-6)
Descriptor:Ig gamma-1 chain C region, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Humm, A., Lobner, E., Mlynek, G., Obinger, C., Djinovic-Carugo, K.
Deposit date:2016-04-22
Release date:2017-04-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Fcab-HER2 Interaction: a Menage a Trois. Lessons from X-Ray and Solution Studies.
Structure, 25, 2017
5K64
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CRYSTAL STRUCTURE OF VEGF BINDING IGG1-FC (FCAB 448)
Descriptor:Ig gamma-1 chain C region, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Humm, A., Lobner, E., Kitzmuller, M., Mlynek, G., Obinger, C., Djinovic-Carugo, K.
Deposit date:2016-05-24
Release date:2017-09-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Two-faced Fcab prevents polymerization with VEGF and reveals thermodynamics and the 2.15 angstrom crystal structure of the complex.
MAbs, 9, 2017
5K65
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CRYSTAL STRUCTURE OF VEGF BINDING IGG1-FC (FCAB CT6)
Descriptor:Ig gamma-1 chain C region, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Humm, A., Lobner, E., Kitzmuller, M., Mlynek, G., Obinger, C., Djinovic-Carugo, K.
Deposit date:2016-05-24
Release date:2017-09-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Two-faced Fcab prevents polymerization with VEGF and reveals thermodynamics and the 2.15 angstrom crystal structure of the complex.
MAbs, 9, 2017
5NKV
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CRYSTAL STRUCTURE OF DIMERIC CHLORITE DISMUTASE FROM CYANOTHECE SP. PCC7425 AT PH 9.0 AND 293 K.
Descriptor:Chlorite Dismutase, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Puehringer, D., Schaffner, I., Mlynek, G., Obinger, C., Djinovic-Carugo, K.
Deposit date:2017-04-03
Release date:2018-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular Mechanism of Enzymatic Chlorite Detoxification: Insights from Structural and Kinetic Studies.
ACS Catal, 7, 2017
5NL6
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THE CRYSTAL STRUCTURE OF THE TWO SPECTRIN REPEAT DOMAINS FROM ENTAMOEBA HISTOLYTICA
Descriptor:Calponin domain family protein, BETA-MERCAPTOETHANOL
Authors:Pinotsis, N., Djinovic-Carugo, K., Khan, M.B.
Deposit date:2017-04-04
Release date:2018-05-16
Last modified:2020-11-04
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Calcium modulates the domain flexibility and function of an alpha-actinin similar to the ancestral alpha-actinin.
Proc.Natl.Acad.Sci.USA, 117, 2020
5NL7
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THE CRYSTAL STRUCTURE OF THE ACTIN BINDING DOMAIN (ABD) OF ALPHA ACTININ FROM ENTAMOEBA HISTOLYTICA
Descriptor:Calponin homology domain protein putative, CALCIUM ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Pinotsis, N., Djinovic-Carugo, K., Khan, M.B.
Deposit date:2017-04-04
Release date:2018-05-16
Last modified:2020-11-04
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Calcium modulates the domain flexibility and function of an alpha-actinin similar to the ancestral alpha-actinin.
Proc.Natl.Acad.Sci.USA, 117, 2020
171916
PDB entries from 2020-12-02