6Q2V

Crystal structure of SPOC domain of human PHD-finger protein 3 (PHF3)

Summary for 6Q2V

• Entry DOI: 10.2210/pdb6q2v/pdb
• Related: 6IC8 6IC9
• Descriptor: PHD finger protein 3, GLYCEROL (3 entities in total)
• Functional Keywords: spoc domain, phf3, transcription
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 8
• Total formula weight: 147374.04

Authors

Grishkovskaya, I.,Slade, D.,Djinovic-Carugo, K. (deposition date: 2018-12-03, release date: 2020-07-15, Last modification date: 2021-10-27)

• Primary citation: Appel, L.M.,Franke, V.,Bruno, M.,Grishkovskaya, I.,Kasiliauskaite, A.,Kaufmann, T.,Schoeberl, U.E.,Puchinger, M.G.,Kostrhon, S.,Ebenwaldner, C.,Sebesta, M.,Beltzung, E.,Mechtler, K.,Lin, G.,Vlasova, A.,Leeb, M.,Pavri, R.,Stark, A.,Akalin, A.,Stefl, R.,Bernecky, C.,Djinovic-Carugo, K.,Slade, D.; PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC; Nat Commun, 12:6078-, 2021; DOI: 10.1038/s41467-021-26360-2

Experimental method

X-RAY DIFFRACTION (2.594 Å)