Author results

6TRO
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CRYSTAL STRUCTURE OF THE T-CELL RECEPTOR GVY01 BOUND TO HLA A2*01-GVYDGREHTV
Descriptor:MHC class I antigen, Beta-2-microglobulin, MAGE-A4 peptide (amino acids 230-239), ...
Authors:Coles, C.H., McMurran, C., Lloyd, A., Hibbert, L., Lupardus, P.J., Cole, D.K., Harper, S.
Deposit date:2019-12-19
Release date:2020-06-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:HLA-bridge guides indirect TCR-peptide specificity for MAGE-A4
J.Biol.Chem., 2020
6TRN
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CRYSTAL STRUCTURE OF HLA A2*01-AVYDGREHTV
Descriptor:MHC class I antigen, Beta-2-microglobulin, MAGE-A4 peptide (amino acids 230-239) variant, ...
Authors:Coles, C.H., McMurran, C., Lloyd, A., Hibbert, L., Lupardus, P.J., Cole, D.K., Harper, S.
Deposit date:2019-12-19
Release date:2020-06-24
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:T Cell Receptor interactions with Human Leukocyte Antigen govern indirect peptide selectivity for the cancer testis antigen MAGE-A4.
J.Biol.Chem., 2020
6RSY
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THE COMPLEX BETWEEN TCR A7B2 AND HUMAN CLASS I MHC HLA-A0201-WT1 WITH THE BOUND RMFPNAPYL PEPTIDE.
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Srikannathasan, V., Robinson, R.A.
Deposit date:2019-05-22
Release date:2020-04-15
Last modified:2020-05-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Specificity of bispecific T cell receptors and antibodies targeting peptide-HLA.
J.Clin.Invest., 130, 2020
6R2L
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NYBR1-A2-SLSKILDTV
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Sami, M.
Deposit date:2019-03-18
Release date:2020-02-26
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:NYBR1-A2-SLSKILDTV
To Be Published
6HCN
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ADENOVIRUS TYPE 5 FIBER KNOB PROTEIN AT 1.49A RESOLUTION
Descriptor:Fiber protein, 1,2-ETHANEDIOL, MAGNESIUM ION
Authors:Rizkallah, P.J., Parker, A.L., Baker, A.T.
Deposit date:2018-08-15
Release date:2019-02-13
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Diversity within the adenovirus fiber knob hypervariable loops influences primary receptor interactions.
Nat Commun, 10, 2019
6HBY
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HLA CLASS II PEPTIDE FLANKING RESIDUES TUNE THE IMMUNOGENICITY OF A HUMAN TUMOR-DERIVED EPITOPE
Descriptor:HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ...
Authors:MacLachlan, B., Rizkallah, P.J., Sewell, A.K., Cole, D.K., Godkin, A.J.
Deposit date:2018-08-13
Release date:2019-08-14
Last modified:2020-01-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope.
J.Biol.Chem., 294, 2019
6G3K
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MHC A02 ALLELE PRESENTING MTSAIGILPV
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Sewell, A.K.
Deposit date:2018-03-26
Release date:2019-09-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Peptide Super-Agonist Enhances T-Cell Responses to Melanoma.
Front Immunol, 10, 2019
6G3J
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MHC A02 ALLELE PRESENTING MTSAIGILVP
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Sewell, A.K.
Deposit date:2018-03-26
Release date:2019-02-20
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Peptide Super-Agonist Enhances T-Cell Responses to Melanoma.
Front Immunol, 10, 2019
6FUR
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F11 T-CELL RECEPTOR RECOGNISING PKYVKQNTLKLAT PEPTIDE PRESENTED BY HLA-DR*0101
Descriptor:Human F11 T-Cell Receptor alpha chain, Human F11 T-Cell Receptor, 1,2-ETHANEDIOL, ...
Authors:Rizkallah, P.J., Cole, D.K.
Deposit date:2018-02-27
Release date:2018-04-18
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FUQ
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F11 T-CELL RECEPTOR RECOGNISING PKYVKQNTLKLAT PEPTIDE PRESENTED BY HLA-DR*0101
Descriptor:Human F11 T-Cell Receptor, Human F11 T-Cell Receptor beta chain, 1,2-ETHANEDIOL, ...
Authors:Rizkallah, P.J., Cole, D.K.
Deposit date:2018-02-27
Release date:2018-04-18
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FUP
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F11 T-CELL RECEPTOR RECOGNISING PKYVKQNTLKLAT PEPTIDE PRESENTED BY HLA-DR*0101
Descriptor:Human F11 T-cell Receptor alpha Chain, Huamn F11 T-Cell Receptor beta chain, 1,2-ETHANEDIOL, ...
Authors:Rizkallah, P.J., Cole, D.K.
Deposit date:2018-02-27
Release date:2018-04-18
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FUO
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F11 T-CELL RECEPTOR RECOGNISING PKYVKQNTLKLAT PEPTIDE PRESENTED BY HLA-DR*0101
Descriptor:Human F11 T-Cell Receptor alpha chain, Human F11 T-Cell Receptor, 1,2-ETHANEDIOL, ...
Authors:Rizkallah, P.J., Cole, D.K.
Deposit date:2018-02-27
Release date:2018-04-18
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FUN
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F11 T-CELL RECEPTOR RECOGNISING PKYVKQNTLKLAT PEPTIDE PRESENTED BY HLA-DR*0101
Descriptor:Huamn F11 T-Cell Receptor alpha chain, Human F11 T-Cell Receptor beta chain, 1,2-ETHANEDIOL, ...
Authors:Rizkallah, P.J., Cole, D.K.
Deposit date:2018-02-27
Release date:2018-04-18
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FUM
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F11 T-CELL RECEPTOR RECOGNISING PKYVKQNTLKLAT PEPTIDE PRESENTED BY HLA-DR*0101
Descriptor:Human F11 T-Cell Receptor alpha chain, Human F11 T-Cell Receptor beta chain, 1,2-ETHANEDIOL, ...
Authors:Rizkallah, P.J., Cole, D.K.
Deposit date:2018-02-27
Release date:2018-04-18
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FRC
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F11 T-CELL RECEPTOR RECOGNISING PKYVKQNTLKLAT PEPTIDE PRESENTED BY HLA-DR*0101
Descriptor:Human T-Cell Receptor F11 alpha Chain, Human T-Cell Receptor beta Chain, 1,2-ETHANEDIOL, ...
Authors:Rizkallah, P.J., Cole, D.K.
Deposit date:2018-02-15
Release date:2018-04-18
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FRB
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F11 T-CELL RECEPTOR RECOGNISING PKYVKQNTLKLAT PEPTIDE PRESENTED BY HLA-DR*0101
Descriptor:Human T-Cell Receptor F11 alpha chain, Human T-Cell Receptor F11 beta Chain
Authors:Rizkallah, P.J., Cole, D.K.
Deposit date:2018-02-15
Release date:2018-04-18
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FRA
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F11 T-CELL RECEPTOR RECOGNISING PKYVKQNTLKLAT PEPTIDE PRESENTED BY HLA-DR*0101
Descriptor:Human T-Cell Receptor F11 alpha Chain, Human T-Cell Receptor F11 beta Chain, 1,2-ETHANEDIOL, ...
Authors:Rizkallah, P.J., Cole, D.K.
Deposit date:2018-02-15
Release date:2018-04-18
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FR9
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F11 T-CELL RECEPTOR RECOGNISING PKYVKQNTLKLAT PEPTIDE PRESENTED BY HLA-DR*0101
Descriptor:T-Cell Receptor F11 alpha chain, T-Cell Receptor F11 beta chain, 1,2-ETHANEDIOL, ...
Authors:Rizkallah, P.J., Cole, D.K.
Deposit date:2018-02-15
Release date:2018-04-18
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FR8
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HA1.7 HUMAN T-CELL RECEPTOR SPECIFIC FOR INFLUENZA VIRUS EPITOPE PKYVKQNTLKLAT PRESENTED BY HUMAN LEUKOCYTE ANTIGEN HLA-DR0101
Descriptor:T-Cell Receptor HA1.7 alpha Chain, T-Cell Receptor HA1.7 beta Chain, SULFATE ION
Authors:Rizkallah, P.J., Cole, D.K.
Deposit date:2018-02-15
Release date:2018-04-18
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FR7
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HA1.7 HUMAN T-CELL RECEPTOR SPECIFIC FOR INFLUENZA VIRUS EPITOPE PKYVKQNTLKLAT PRESENTED BY HUMAN LEUKOCYTE ANTIGEN HLA-DR0101
Descriptor:T-Cell Receptor alpha chain, T-cell Rceceptor beta Chain, 1,2-ETHANEDIOL, ...
Authors:Rizkallah, P.J., Cole, D.K.
Deposit date:2018-02-15
Release date:2018-04-18
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FR6
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HA1.7 HUMAN T-CELL RECEPTOR SPECIFIC FOR INFLUENZA VIRUS EPITOPE PKYVKQNTLKLAT PRESENTED BY HUMAN LEUKOCYTE ANTIGEN HLA-DR0101
Descriptor:Human T-Cell Receptor Alpha Chain, Human T-cell Receptor Beta Chain, SULFATE ION
Authors:Rizkallah, P.J., Cole, D.K.
Deposit date:2018-02-15
Release date:2018-04-18
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FR5
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HA1.7 TCR STUDY OF CDR LOOP FLEXIBILITY
Descriptor:TCR HA1.7 specific for FLU epitope PKYVKQNTLKLAT, alpha chain, beta chain, ...
Authors:Rizkallah, P.J., Cole, D.K.
Deposit date:2018-02-15
Release date:2018-04-18
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FR4
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003 TCR STUDY OF CDR LOOP FLEXIBILITY
Descriptor:TCR 003 alpha chain, TCR 003 Beta Chain, GLYCEROL, ...
Authors:Rizkallah, P.J., Cole, D.K.
Deposit date:2018-02-15
Release date:2018-04-18
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FR3
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003 TCR STUDY OF CDR LOOP FLEXIBILITY
Descriptor:003 TCR Alpha Chain, 003 TCR Beta Chain, 1,2-ETHANEDIOL, ...
Authors:Rizkallah, P.J., Cole, D.K.
Deposit date:2018-02-15
Release date:2018-04-18
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Front Immunol, 9, 2018
6FJQ
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ADENOVIRUS SPECIES 48, FIBER KNOB PROTEIN
Descriptor:Fiber, 1,2-ETHANEDIOL, GLYCEROL, ...
Authors:Rizkallah, P.J., Parker, A.L., Baker, A.T.
Deposit date:2018-01-22
Release date:2019-02-06
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Diversity within the adenovirus fiber knob hypervariable loops influences primary receptor interactions.
Nat Commun, 10, 2019