Author results

1RS6
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RAT NEURONAL NOS HEME DOMAIN WITH D-LYSINE-D-NITROARGININE AMIDE BOUND
分子名称:Nitric-oxide synthase, brain, D-MANNITOL, ...
著者Flinspach, M., Li, H., Jamal, J., Yang, W., Huang, H., Silverman, R.B., Poulos, T.L.
登録日2003-12-09
公開日2004-05-18
最終更新日2011-09-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structures of the Neuronal and Endothelial Nitric Oxide Synthase Heme Domain with d-Nitroarginine-Containing Dipeptide Inhibitors Bound.
Biochemistry, 43, 2004
1RS7
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RAT NEURONAL NOS HEME DOMAIN WITH D-PHENYLALANINE-D-NITROARGININE AMIDE BOUND
分子名称:Nitric-oxide synthase, brain, ACETATE ION, ...
著者Flinspach, M., Li, H., Jamal, J., Yang, W., Huang, H., Silverman, R.B., Poulos, T.L.
登録日2003-12-09
公開日2004-05-18
最終更新日2011-09-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structures of the Neuronal and Endothelial Nitric Oxide Synthase Heme Domain with d-Nitroarginine-Containing Dipeptide Inhibitors Bound.
Biochemistry, 43, 2004
1RS8
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BOVINE ENDOTHELIAL NOS HEME DOMAIN WITH D-LYSINE-D-NITROARGININE AMIDE BOUND
分子名称:Nitric-oxide synthase, endothelial, CACODYLATE ION, ...
著者Flinspach, M., Li, H., Jamal, J., Yang, W., Huang, H., Silverman, R.B., Poulos, T.L.
登録日2003-12-09
公開日2004-06-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of the neuronal and endothelial nitric oxide synthase heme domain with D-nitroarginine-containing dipeptide inhibitors bound.
Biochemistry, 43, 2004
1RS9
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BOVINE ENDOTHELIAL NOS HEME DOMAIN WITH D-PHENYLALANINE-D-NITROARGININE AMIDE BOUND
分子名称:Nitric-oxide synthase, endothelial, CACODYLATE ION, ...
著者Flinspach, M., Li, H., Jamal, J., Yang, W., Huang, H., Silverman, R.B., Poulos, T.L.
登録日2003-12-09
公開日2004-06-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structures of the neuronal and endothelial nitric oxide synthase heme domain with D-nitroarginine-containing dipeptide inhibitors bound.
Biochemistry, 43, 2004
1LZX
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RAT NEURONAL NOS HEME DOMAIN WITH NG-HYDROXY-L-ARGININE BOUND
分子名称:Nitric-oxide synthase, ACETATE ION, ZINC ION, ...
著者Li, H., Shimizu, H., Flinspach, M., Jamal, J., Yang, W., Xian, M., Cai, T., Wen, E.Z., Jia, Q., Wang, P.G., Poulos, T.L.
登録日2002-06-11
公開日2002-11-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Novel Binding Mode of N-Alkyl-N'-Hydroxyguanidine to Neuronal Nitric Oxide Synthase Provides Mechanistic Insights into NO Biosynthesis
Biochemistry, 41, 2002
1LZZ
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RAT NEURONAL NOS HEME DOMAIN WITH N-ISOPROPYL-N'-HYDROXYGUANIDINE BOUND
分子名称:Nitric-oxide synthase, ACETATE ION, ZINC ION, ...
著者Li, H., Shimizu, H., Flinspach, M., Jamal, J., Yang, W., Xian, M., Cai, T., Wen, E.Z., Jia, Q., Wang, P.G., Poulos, T.L.
登録日2002-06-11
公開日2002-11-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The Novel Binding Mode of N-Alkyl-N'-Hydroxyguanidine to Neuronal Nitric Oxide Synthase Provides Mechanistic Insights into NO Biosynthesis
Biochemistry, 41, 2002
1M00
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RAT NEURONAL NOS HEME DOMAIN WITH N-BUTYL-N'-HYDROXYGUANIDINE BOUND
分子名称:Nitric-oxide synthase, ACETATE ION, ZINC ION, ...
著者Li, H., Shimizu, H., Flinspach, M., Jamal, J., Yang, W., Xian, M., Cai, T., Wen, E.Z., Jia, Q., Wang, P.G., Poulos, T.L.
登録日2002-06-11
公開日2002-11-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The Novel Binding Mode of N-Alkyl-N'-Hydroxyguanidine to Neuronal Nitric Oxide Synthase Provides Mechanistic Insights into NO Biosynthesis
Biochemistry, 41, 2002
2M4X
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ANALYSIS OF THE STRUCTURAL AND MOLECULAR BASIS OF VOLTAGE-SENSITIVE SODIUM CHANNEL INHIBITION BY THE SPIDER TOXIN, HUWENTOXIN-IV (-TRTX-HH2A).
分子名称:Mu-theraphotoxin-Hh2a
著者Gibbs, A., Flinspach, M.
登録日2013-02-11
公開日2013-06-19
最終更新日2013-08-28
実験手法SOLUTION NMR
主引用文献Analysis of the Structural and Molecular Basis of Voltage-sensitive Sodium Channel Inhibition by the Spider Toxin Huwentoxin-IV ( mu-TRTX-Hh2a).
J.Biol.Chem., 288, 2013
2M50
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ANALYSIS OF THE STRUCTURAL AND MOLECULAR BASIS OF VOLTAGE-SENSITIVE SODIUM CHANNEL INHIBITION BY THE SPIDER TOXIN, HUWENTOXIN-IV (-TRTX-HH2A).
分子名称:Mu-theraphotoxin-Hh2a
著者Gibbs, A., Minassian, N., Flinspach, M., Wickenden, A.
登録日2013-02-12
公開日2013-06-19
最終更新日2013-08-28
実験手法SOLUTION NMR
主引用文献Analysis of the Structural and Molecular Basis of Voltage-sensitive Sodium Channel Inhibition by the Spider Toxin Huwentoxin-IV ( mu-TRTX-Hh2a).
J.Biol.Chem., 288, 2013
5TCZ
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NMR SOLUTION STRUCTURE OF ENGINEERED PROTOXIN-II ANALOG
分子名称:Beta/omega-theraphotoxin-Tp2a
著者Gibbs, A.C., Wickenden, A.D.
登録日2016-09-16
公開日2017-01-18
実験手法SOLUTION NMR
主引用文献Insensitivity to pain induced by a potent selective closed-state Nav1.7 inhibitor.
Sci Rep, 7, 2017
1P6H
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RAT NEURONAL NOS HEME DOMAIN WITH L-N(OMEGA)-NITROARGININE-2,4-L-DIAMINOBUTYRIC AMIDE BOUND
分子名称:Nitric-oxide synthase, brain, ACETATE ION, ...
著者Flinspach, M.L., Li, H., Jamal, J., Yang, W., Huang, H., Hah, J.-M., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
登録日2003-04-29
公開日2004-01-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
1P6I
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RAT NEURONAL NOS HEME DOMAIN WITH (4S)-N-(4-AMINO-5-[AMINOETHYL]AMINOPENTYL)-N'-NITROGUANIDINE BOUND
分子名称:Nitric-oxide synthase, brain, ACETATE ION, ...
著者Flinspach, M.L., Li, H., Jamal, J., Yang, W., Huang, H., Hah, J.-M., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
登録日2003-04-29
公開日2004-01-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
1P6J
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RAT NEURONAL NOS HEME DOMAIN WITH L-N(OMEGA)-NITROARGININE-(4R)-AMINO-L-PROLINE AMIDE BOUND
分子名称:Nitric-oxide synthase, brain, ACETATE ION, ...
著者Flinspach, M.L., Li, H., Jamal, J., Yang, W., Huang, H., Hah, J.-M., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
登録日2003-04-29
公開日2004-01-13
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
1P6K
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RAT NEURONAL NOS D597N MUTANT HEME DOMAIN WITH L-N(OMEGA)-NITROARGININE-2,4-L-DIAMINOBUTYRIC AMIDE BOUND
分子名称:Nitric-oxide synthase, brain, D-MANNITOL, ...
著者Flinspach, M.L., Li, H., Jamal, J., Yang, W., Huang, H., Hah, J.-M., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
登録日2003-04-29
公開日2004-01-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
1P6L
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BOVINE ENDOTHELIAL NOS HEME DOMAIN WITH L-N(OMEGA)-NITROARGININE-2,4-L-DIAMINOBUTYRIC AMIDE BOUND
分子名称:Nitric-oxide synthase, endothelial, CACODYLATE ION, ...
著者Flinspach, M.L., Li, H., Jamal, J., Yang, W., Huang, H., Hah, J.-M., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
登録日2003-04-29
公開日2004-01-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
1P6M
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BOVINE ENDOTHELIAL NOS HEME DOMAIN WITH (4S)-N-(4-AMINO-5-[AMINOETHYL]AMINOPENTYL)-N'-NITROGUANIDINE BOUND
分子名称:Nitric-oxide synthase, endothelial, CACODYLATE ION, ...
著者Flinspach, M.L., Li, H., Jamal, J., Yang, W., Huang, H., Hah, J.-M., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
登録日2003-04-29
公開日2004-01-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
1P6N
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BOVINE ENDOTHELIAL NOS HEME DOMAIN WITH L-N(OMEGA)-NITROARGININE-(4R)-AMINO-L-PROLINE AMIDE BOUND
分子名称:Nitric-oxide synthase, endothelial, CACODYLATE ION, ...
著者Flinspach, M.L., Li, H., Jamal, J., Yang, W., Huang, H., Hah, J.-M., Gomez-Vidal, J.A., Litzinger, E.A., Silverman, R.B., Poulos, T.L.
登録日2003-04-29
公開日2004-01-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
2M4Z
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ANALYSIS OF THE STRUCTURAL AND MOLECULAR BASIS OF VOLTAGE-SENSITIVE SODIUM CHANNEL INHIBITION BY THE SPIDER TOXIN, HUWENTOXIN-IV (-TRTX-HH2A).
分子名称:Mu-theraphotoxin-Hh2a
著者Gibbs, A.
登録日2013-02-12
公開日2013-06-19
最終更新日2013-08-28
実験手法SOLUTION NMR
主引用文献Analysis of the Structural and Molecular Basis of Voltage-sensitive Sodium Channel Inhibition by the Spider Toxin Huwentoxin-IV ( mu-TRTX-Hh2a).
J.Biol.Chem., 288, 2013
2HX2
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BOVINE ENOS HEME DOMAIN COMPLEXED WITH (4S)-N-{4-AMINO-5-[(2-AMINOETHYL)-HYDROXYAMINO]-PENTYL}-N'-NITROGUANIDINE
分子名称:Nitric-oxide synthase, CACODYLATE ION, ACETATE ION, ...
著者Igarashi, J., Li, H., Poulos, T.L.
登録日2006-08-02
公開日2007-04-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure-Based Design and Synthesis of N(omega)-Nitro-l-Arginine-Containing Peptidomimetics as Selective Inhibitors of Neuronal Nitric Oxide Synthase. Displacement of the Heme Structural Water.
J.Med.Chem., 50, 2007
2HX3
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RAT NNOS HEME DOMAIN COMPLEXED WITH (4S)-N-{4-AMINO-5-[(2-AMINOETHYL)-HYDROXYAMINO]-PENTYL}-N'-NITROGUANIDINE
分子名称:Nitric-oxide synthase, ACETATE ION, ZINC ION, ...
著者Igarashi, J., Li, H., Poulos, T.L.
登録日2006-08-02
公開日2007-04-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure-Based Design and Synthesis of N(omega)-Nitro-l-Arginine-Containing Peptidomimetics as Selective Inhibitors of Neuronal Nitric Oxide Synthase. Displacement of the Heme Structural Water.
J.Med.Chem., 50, 2007
2HX4
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RAT NNOS HEME DOMAIN COMPLEXED WITH 4-N-(NW-NITRO-L-ARGININYL)-TRANS-4-HYDROXYAMINO-L-PROLINE AMIDE
分子名称:Nitric-oxide synthase, ACETATE ION, ZINC ION, ...
著者Igarashi, J., Li, H., Poulos, T.L.
登録日2006-08-02
公開日2007-04-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure-Based Design and Synthesis of N(omega)-Nitro-l-Arginine-Containing Peptidomimetics as Selective Inhibitors of Neuronal Nitric Oxide Synthase. Displacement of the Heme Structural Water.
J.Med.Chem., 50, 2007