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2M4Z

Analysis of the structural and molecular basis of voltage-sensitive sodium channel inhibition by the spider toxin, Huwentoxin-IV (-TRTX-Hh2a).

Summary for 2M4Z
Entry DOI10.2210/pdb2m4z/pdb
Related2M4X 2M50
NMR InformationBMRB: 19030
DescriptorMu-theraphotoxin-Hh2a (1 entity in total)
Functional Keywordsvenom toxin, toxin
Biological sourceHaplopelma schmidti (Chinese bird spider,Chinese golden earth tiger)
Cellular locationSecreted: P83303
Total number of polymer chains1
Total formula weight4005.73
Authors
Gibbs, A. (deposition date: 2013-02-12, release date: 2013-06-19, Last modification date: 2023-06-14)
Primary citationMinassian, N.A.,Gibbs, A.,Shih, A.Y.,Liu, Y.,Neff, R.A.,Sutton, S.W.,Mirzadegan, T.,Connor, J.,Fellows, R.,Husovsky, M.,Nelson, S.,Hunter, M.J.,Flinspach, M.,Wickenden, A.D.
Analysis of the Structural and Molecular Basis of Voltage-sensitive Sodium Channel Inhibition by the Spider Toxin Huwentoxin-IV ( mu-TRTX-Hh2a).
J.Biol.Chem., 288:22707-22720, 2013
Cited by
PubMed: 23760503
DOI: 10.1074/jbc.M113.461392
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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