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7FDN
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BU of 7fdn by Molmil
Crystal structure of transcription factor WER in complex with EGL3
Descriptor: CHLORIDE ION, GLYCEROL, SODIUM ION, ...
Authors:Luo, Q, Wang, B.
Deposit date:2021-07-17
Release date:2022-07-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into partner selection for MYB and bHLH transcription factor complexes.
Nat.Plants, 8, 2021
7FDM
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BU of 7fdm by Molmil
Crystal structure of transcription factor MYB29 in complex with MYC3
Descriptor: Transcription factor MYB29, Transcription factor MYC3
Authors:Luo, Q, Wang, B.
Deposit date:2021-07-17
Release date:2022-07-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights into partner selection for MYB and bHLH transcription factor complexes.
Nat.Plants, 8, 2021
7FDL
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BU of 7fdl by Molmil
Crystal structure of transcription factor WER in complex with EGL3
Descriptor: Transcription factor EGL1, Transcription factor WER
Authors:Luo, Q, Wang, B.
Deposit date:2021-07-17
Release date:2022-07-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.897 Å)
Cite:Structural insights into partner selection for MYB and bHLH transcription factor complexes.
Nat.Plants, 8, 2021
7F2F
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BU of 7f2f by Molmil
The complex of DNA with the C-terminal domain of TYE7 from Saccharomyces cerevisiae.
Descriptor: DNA (5'-D(*CP*AP*GP*AP*TP*CP*AP*TP*GP*TP*GP*TP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*CP*AP*CP*AP*CP*AP*TP*GP*AP*TP*CP*T)-3'), Serine-rich protein TYE7
Authors:Gui, W.
Deposit date:2021-06-10
Release date:2021-10-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structure of the complex of DNA with the C-terminal domain of TYE7 from Saccharomyces cerevisiae.
Acta Crystallogr.,Sect.F, 77, 2021
6YGJ
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BU of 6ygj by Molmil
small-molecule stabilizer of 14-3-3 and the Carbohydrate Response Element Binding Protein (ChREBP) protein-protein interaction
Descriptor: 14-3-3 protein beta/alpha, Carbohydrate-responsive element-binding protein, [2-[2-oxidanylidene-2-(2-phenylethylamino)ethoxy]phenyl]phosphonic acid
Authors:Ottmann, C, Visser, E.J.
Deposit date:2020-03-27
Release date:2020-09-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structure-based evolution of a promiscuous inhibitor to a selective stabilizer of protein-protein interactions.
Nat Commun, 11, 2020
6U2U
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BU of 6u2u by Molmil
Helix-Loop-helix motif of mouse DNA-binding protein inhibitor ID-1
Descriptor: DNA-binding protein inhibitor ID-1
Authors:Benezra, R, Pavletich, N.P, Goldgur, Y, Gall, A.-L.
Deposit date:2019-08-20
Release date:2019-10-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization.
Cell Rep, 29, 2019
6QTV
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BU of 6qtv by Molmil
Crystal structure of an Arabidopsis WD40 domain in complex with an atypical bHLH transcription factor
Descriptor: E3 ubiquitin-protein ligase COP1, GLYCEROL, MALONATE ION, ...
Authors:Hothorn, M, Lau, K.
Deposit date:2019-02-25
Release date:2019-07-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Plant photoreceptors and their signaling components compete for COP1 binding via VP peptide motifs.
Embo J., 38, 2019
6QPJ
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BU of 6qpj by Molmil
Human CLOCK PAS-A domain
Descriptor: Circadian locomoter output cycles protein kaput
Authors:Kwon, H, Freeman, S.L, Moody, P.C.E, Raven, E.L, Basran, J.
Deposit date:2019-02-14
Release date:2019-09-25
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.315 Å)
Cite:Heme binding to human CLOCK affects interactions with the E-box.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OD5
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BU of 6od5 by Molmil
Human TCF4 C-terminal bHLH domain in Complex with 12-bp Oligonucleotide Containing E-box Sequence with 5-carboxylcytosines
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DNA (5'-D(*AP*(1CC)P*GP*CP*AP*CP*GP*TP*GP*(1CC)P*G)-3'), ...
Authors:Horton, J.R, Cheng, X, Yang, J.
Deposit date:2019-03-25
Release date:2019-05-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis for preferential binding of human TCF4 to DNA containing 5-carboxylcytosine.
Nucleic Acids Res., 47, 2019
6OD4
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BU of 6od4 by Molmil
Human TCF4 C-terminal bHLH domain in Complex with 11-bp Oligonucleotide Containing E-box Sequence
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*TP*AP*CP*AP*CP*GP*TP*GP*TP*A)-3'), Transcription factor 4
Authors:Horton, J.R, Cheng, X, Yang, J.
Deposit date:2019-03-25
Release date:2019-05-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.699 Å)
Cite:Structural basis for preferential binding of human TCF4 to DNA containing 5-carboxylcytosine.
Nucleic Acids Res., 47, 2019
6OD3
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BU of 6od3 by Molmil
Human TCF4 C-terminal bHLH domain in Complex with 13-bp Oligonucleotide Containing E-box Sequence
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DNA (5'-D(*CP*AP*TP*AP*CP*AP*CP*GP*TP*GP*TP*AP*T)-3'), ...
Authors:Horton, J.R, Cheng, X, Yang, J.
Deposit date:2019-03-25
Release date:2019-05-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.494 Å)
Cite:Structural basis for preferential binding of human TCF4 to DNA containing 5-carboxylcytosine.
Nucleic Acids Res., 47, 2019
6MGN
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BU of 6mgn by Molmil
mouse Id1 (51-104) - human hE47 (348-399) complex
Descriptor: DNA-binding protein inhibitor ID-1, Transcription factor E2-alpha
Authors:Benezra, R, Pavletich, N.P, Gall, A.-L, Goldgur, Y.
Deposit date:2018-09-14
Release date:2019-09-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization.
Cell Rep, 29, 2019
6MGM
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BU of 6mgm by Molmil
Helix-Loop-helix motif of mouse DNA-binding protein inhibitor ID-1
Descriptor: DNA-binding protein inhibitor ID-1
Authors:Benezra, R, Pavletich, N.P, Goldgur, Y, Gall, A.-L.
Deposit date:2018-09-14
Release date:2019-09-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.791 Å)
Cite:A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization.
Cell Rep, 29, 2019
6FX5
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BU of 6fx5 by Molmil
MITF dimerization mutant
Descriptor: Microphthalmia-associated transcription factor, SULFATE ION
Authors:Pogenberg, V, Milewski, M, Wilmanns, M.
Deposit date:2018-03-08
Release date:2019-03-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Mechanism of conditional partner selectivity in MITF/TFE family transcription factors with a conserved coiled coil stammer motif.
Nucleic Acids Res., 48, 2020
6A5S
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BU of 6a5s by Molmil
Structure of 14-3-3 gamma in complex with TFEB 14-3-3 binding motif
Descriptor: 14-3-3 protein gamma, MAGNESIUM ION, SODIUM ION, ...
Authors:Xu, Y, Ren, J.Q, Feng, W.
Deposit date:2018-06-25
Release date:2019-02-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:YWHA/14-3-3 proteins recognize phosphorylated TFEB by a noncanonical mode for controlling TFEB cytoplasmic localization.
Autophagy, 15, 2019
6A5Q
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BU of 6a5q by Molmil
Structure of 14-3-3 beta in complex with TFEB 14-3-3 binding motif
Descriptor: 14-3-3 protein beta/alpha, MALONIC ACID, TFEB pS211-peptide
Authors:Xu, Y, Ren, J.Q, Feng, W.
Deposit date:2018-06-25
Release date:2019-02-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:YWHA/14-3-3 proteins recognize phosphorylated TFEB by a noncanonical mode for controlling TFEB cytoplasmic localization.
Autophagy, 15, 2019
5ZD4
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BU of 5zd4 by Molmil
Crystal structure of MBP-fused BIL1/BZR1 in complex with double-stranded DNA
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*TP*TP*CP*AP*CP*AP*CP*GP*TP*GP*TP*GP*AP*AP*A)-3'), Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1, ...
Authors:Nosaki, S, Miyakawa, T, Xu, Y, Nakamura, A, Hirabayashi, K, Tanokura, M.
Deposit date:2018-02-22
Release date:2018-08-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structural basis for brassinosteroid response by BIL1/BZR1.
Nat Plants, 4, 2018
5Y7Y
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BU of 5y7y by Molmil
Crystal structure of AhRR/ARNT complex
Descriptor: Aryl hydrocarbon receptor nuclear translocator, Aryl hydrocarbon receptor repressor, GLYCEROL
Authors:Sakurai, S, Shimizu, T, Ohto, U.
Deposit date:2017-08-18
Release date:2017-09-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The crystal structure of the AhRR-ARNT heterodimer reveals the structural basis of the repression of AhR-mediated transcription.
J. Biol. Chem., 292, 2017
5T5X
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BU of 5t5x by Molmil
High resolution structure of mouse Cryptochrome 1
Descriptor: CHLORIDE ION, Cryptochrome-1
Authors:Michael, A.K, Tripathi, S, Partch, C.L.
Deposit date:2016-08-31
Release date:2017-02-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Formation of a repressive complex in the mammalian circadian clock is mediated by the secondary pocket of CRY1.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5T0Q
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BU of 5t0q by Molmil
Crystal structure of the Myc3 N-terminal domain [44-242] in complex with JAZ10 Jas domain [166-192] from arabidopsis
Descriptor: Protein TIFY 9, Transcription factor MYC3
Authors:Ke, J, Zhang, F, Brunzelle, J.S, He, S.Y, Xu, H.E, Melcher, K.
Deposit date:2016-08-16
Release date:2017-01-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural insights into alternative splicing-mediated desensitization of jasmonate signaling.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5T0F
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BU of 5t0f by Molmil
Crystal structure of the Myc3 N-terminal domain [44-242] in complex with JAZ10 CMID domain [16-58] from arabidopsis
Descriptor: Protein TIFY 9, Transcription factor MYC3
Authors:Ke, J, Zhang, F, Brunzelle, J.S, He, S.Y, Xu, H.E, Melcher, K.
Deposit date:2016-08-16
Release date:2017-01-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into alternative splicing-mediated desensitization of jasmonate signaling.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5SY7
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BU of 5sy7 by Molmil
Crystal Structure of the Heterodimeric NPAS3-ARNT Complex with HRE DNA
Descriptor: Aryl hydrocarbon receptor nuclear translocator, DNA (5'-D(*CP*AP*CP*GP*AP*CP*CP*CP*GP*CP*AP*CP*GP*TP*AP*CP*GP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*GP*CP*TP*GP*CP*GP*TP*AP*CP*GP*TP*GP*CP*GP*GP*GP*TP*CP*GP*T)-3'), ...
Authors:Wu, D, Su, X, Potluri, N, Kim, Y, Rastinejad, F.
Deposit date:2016-08-10
Release date:2016-11-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors.
Elife, 5, 2016
5SY5
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BU of 5sy5 by Molmil
Crystal Structure of the Heterodimeric NPAS1-ARNT Complex
Descriptor: Aryl hydrocarbon receptor nuclear translocator, Neuronal PAS domain-containing protein 1
Authors:Wu, D, Su, X, Potluri, N, Kim, Y, Rastinejad, F.
Deposit date:2016-08-10
Release date:2016-11-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.201 Å)
Cite:NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors.
Elife, 5, 2016
5NJ8
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BU of 5nj8 by Molmil
Structural basis for aryl hydrocarbon receptor mediated gene activation
Descriptor: ACETATE ION, Aryl hydrocarbon receptor, Aryl hydrocarbon receptor nuclear translocator, ...
Authors:Daumke, O, Schulte, K.W.
Deposit date:2017-03-28
Release date:2017-06-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural Basis for Aryl Hydrocarbon Receptor-Mediated Gene Activation.
Structure, 25, 2017
5GNJ
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BU of 5gnj by Molmil
Structure of a transcription factor and DNA complex
Descriptor: DNA (5'-D(*AP*GP*GP*AP*AP*CP*AP*CP*GP*TP*GP*AP*CP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*GP*TP*CP*AP*CP*GP*TP*GP*TP*TP*CP*C)-3'), Transcription factor MYC2
Authors:Lian, T, Xu, Y, Su, X.
Deposit date:2016-07-21
Release date:2017-05-10
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of Tetrameric Arabidopsis MYC2 Reveals the Mechanism of Enhanced Interaction with DNA.
Cell Rep, 19, 2017

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