6A5S

Structure of 14-3-3 gamma in complex with TFEB 14-3-3 binding motif

Summary for 6A5S

Descriptor14-3-3 protein gamma, TFEB pS211-peptide, SODIUM ION, ... (5 entities in total)
Functional Keywordsphosphoserin, regulation, transcription factor, transcription
Biological sourceHomo sapiens (Human)
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Total number of polymer chains8
Total molecular weight119972.43
Authors
Xu, Y.,Ren, J.Q.,Feng, W. (deposition date: 2018-06-25, release date: 2019-02-13, Last modification date: 2019-02-27)
Primary citation
Xu, Y.,Ren, J.,He, X.,Chen, H.,Wei, T.,Feng, W.
YWHA/14-3-3 proteins recognize phosphorylated TFEB by a noncanonical mode for controlling TFEB cytoplasmic localization.
Autophagy, :1-14, 2019
PubMed: 30653408 (PDB entries with the same primary citation)
DOI: 10.1080/15548627.2019.1569928
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.099 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.22730 0.9% 2.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6a5s
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Molmil generated image of 6a5s
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Molmil generated image of 6a5s
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More Biological unit images

Molmil generated image of 6a5s
no rotation
Molmil generated image of 6a5s
rotated about x axis by 90°
Molmil generated image of 6a5s
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (6a5s.pdb2.gz [87.56 KB])
Coordinate files for Biological unit (6a5s.pdb1.gz [88.4 KB])